Jan Vinjé,Mary K Estes,Pedro Esteves et al.
Jan Vinjé et al.
The family Caliciviridae includes viruses with single-stranded, positive-sense RNA genomes of 7.4-8.3 kb. The most clinically important representatives are human noroviruses, which are a leading cause of acute gastroenteritis in humans. Vir...
Single-particle measurements of filamentous influenza virions reveal damage induced by freezing [0.03%]
单个粒子测量表明冷冻对丝状流感病毒颗粒有损伤作用
Jack C Hirst,Edward C Hutchinson
Jack C Hirst
Clinical isolates of influenza virus produce pleiomorphic virions, ranging from small spheres to elongated filaments. The filaments are seemingly adaptive in natural infections, but their basic functional properties are poorly understood an...
Rotavirus G9P[4], G9P[6] and G1P[6] strains isolated from children with acute gastroenteritis in Pune, western India, 2013-2015: evidence for recombination in genes encoding VP3, VP4 and NSP1 [0.03%]
印度西部浦那2013-2015年从急性胃肠炎患儿中分离的轮状病毒G9P[4]、G9P[6]和G1P[6]株：VP3、VP4和NSP1基因重组证据
Vaishali S Tatte,Deepthy Maran,Atul M Walimbe et al.
Vaishali S Tatte et al.
Species A rotaviruses (RVAs) are genetically diverse pathogens. These are the most evolutionarily adaptable organisms, with a multitude of mechanisms for evolutionary change. To date, full-genome classification has been proved to be an exce...
Comparative evaluation of pathogenicity of three isolates of vesicular stomatitis virus (Indiana serotype) in pigs [0.03%]
三种印第安纳型口蹄疫病毒株感染猪的致病性比较研究
Igor Morozov,A Sally Davis,Steven Ellsworth et al.
Igor Morozov et al.
Vesicular stomatitis (VS) is a notifiable disease of livestock affecting cattle, horses, pigs and humans. Vesicular stomatitis virus (VSV) serotypes Indiana and New Jersey are endemic to Central America; however, they also cause sporadic an...
Increased serum sialic acid is associated with morbidity and mortality in a murine model of dengue disease [0.03%]
血清唾液酸与登革热小鼠模型发病率和死亡率相关性研究
Diego A Espinosa,P Robert Beatty,Henry Puerta-Guardo et al.
Diego A Espinosa et al.
Dengue virus (DENV) causes the most prevalent arboviral infection of humans, resulting in a spectrum of outcomes, ranging from asymptomatic infection to dengue fever to severe dengue characterized by vascular leakage and shock. Previously, ...
Mutated influenza A virus exhibiting reduced susceptibility to baloxavir marboxil from an experimentally infected horse [0.03%]
从实验感染的马匹中分离到对玛巴洛沙韦低敏感性的甲型流感病毒变异株
Manabu Nemoto,Norihisa Tamura,Hiroshi Bannai et al.
Manabu Nemoto et al.
Baloxavir marboxil (BXM), an inhibitor of the cap-dependent endonuclease of the influenza virus polymerase acidic protein (PA), exerts an antiviral effect against influenza A virus. It has been available in Japan since March 2018. This stud...
Chimeric viruses of the insect-specific flavivirus Palm Creek with structural proteins of vertebrate-infecting flaviviruses identify barriers to replication of insect-specific flaviviruses in vertebrate cells [0.03%]
具有节肢动物特异性黄病毒Palm Creek病毒结构蛋白的嵌合体病毒揭示了节肢动物特异性黄病毒感染脊椎动物细胞的障碍
Thisun B H Piyasena,Natalee D Newton,Jody Hobson-Peters et al.
Thisun B H Piyasena et al.
Here we report the generation of novel chimeric flaviviruses, which express the prM and E proteins of either dengue or Zika viruses on the genomic backbone of Palm Creek virus (PCV), an insect-specific flavivirus. The chimeric virus particl...
Discovery of two highly divergent negative-sense RNA viruses associated with the parasitic nematode, Capillaria hepatica, in wild Mus musculus from New York City [0.03%]
纽约市野外实验小鼠寄生蠕虫中与负链rna病毒相关的两种高度变异病毒的发现
Simon H Williams,Xiaoyu Che,Alexandra Oleynik et al.
Simon H Williams et al.
Recent advances in high-throughput sequencing technology have led to a rapid expansion in the number of viral sequences associated with samples from vertebrates, invertebrates and environmental samples. Accurate host identification can be d...
Structure-function analysis of the equine hepacivirus 5' untranslated region highlights the conservation of translational mechanisms across the hepaciviruses [0.03%]
马肝炎病毒5'非翻译区结构功能分析揭示其翻译机制在肝炎病毒科中的保守性
Joseph Lattimer,Hazel Stewart,Nicolas Locker et al.
Joseph Lattimer et al.
Equine hepacivirus (EHcV) (now also classified as hepacivirus A) is the closest genetic relative to hepatitis C virus (HCV) and is proposed to have diverged from HCV within the last 1000 years. The 5' untranslated regions (UTRs) of both HCV...
Equine herpesvirus 1 infection orchestrates the expression of chemokines in equine respiratory epithelial cells [0.03%]
马疱疹病毒1型感染调控马呼吸道上皮细胞中化学趋化因子的表达
Katrien C K Poelaert,Jolien Van Cleemput,Kathlyn Laval et al.
Katrien C K Poelaert et al.
The ancestral equine herpesvirus 1 (EHV1), closely related to human herpes viruses, exploits leukocytes to reach its target organs, accordingly evading the immune surveillance system. Circulating EHV1 strains can be divided into abortigenic...