Marc Fuchs,Moshe Bar-Joseph,Thierry Candresse et al.
Marc Fuchs et al.
Viruses in the family Closteroviridae have a mono-, bi- or tripartite positive-sense RNA genome of 13-19 kb, and non-enveloped, filamentous particles 650-2200 nm long and 12 nm in diameter. They infect plants, mainly dicots, many of which a...
Analysis of genomic-length HBV sequences to determine genotype and subgenotype reference sequences [0.03%]
分析基因组长度的HBV序列以确定基因型和亚基因型参考序列
Anna L McNaughton,Peter A Revill,Margaret Littlejohn et al.
Anna L McNaughton et al.
Hepatitis B virus (HBV) is a diverse, partially double-stranded DNA virus, with 9 genotypes (A-I), and a putative 10th genotype (J), characterized thus far. Given the broadening interest in HBV sequencing, there is an increasing requirement...
African horse sickness virus NS4 is a nucleocytoplasmic protein that localizes to PML nuclear bodies [0.03%]
非洲马瘟病毒NS4是一种核质蛋白，定位于PML核体中
Shareen Boughan,A Christiaan Potgieter,Vida van Staden
Shareen Boughan
African horse sickness virus (AHSV) is the causative agent of the often fatal disease African horse sickness in equids. The non-structural protein NS4 is the only AHSV protein that localizes to the nucleus. Here we report that all AHSV refe...
Leaky scanning translation generates a second A49 protein that contributes to vaccinia virus virulence [0.03%]
漏扫描翻译产生第二个A49蛋白以增强痘病毒的毒力
Sarah Neidel,Alice A Torres,Hongwei Ren et al.
Sarah Neidel et al.
Vaccinia virus (VACV) strain Western Reserve gene A49L encodes a small intracellular protein with a Bcl-2 fold that is expressed early during infection and has multiple functions. A49 co-precipitates with the E3 ubiquitin ligase β-TrCP and...
Parainfluenza virus 5 fusion protein maintains pre-fusion stability but not fusogenic activity following mutation of a transmembrane leucine/isoleucine domain [0.03%]
突变跨膜位点的副流感病毒5融合蛋白及其稳定性和融合活性的研究
Jean Mawuena Branttie,Rebecca Ellis Dutch
Jean Mawuena Branttie
The paramyxoviruses Hendra virus (HeV) and parainfluenza virus 5 (PIV5) require the fusion (F) protein to efficiently infect cells. For fusion to occur, F undergoes dramatic, essentially irreversible conformational changes to merge the vira...
West Nile Virus fidelity modulates the capacity for host cycling and adaptation [0.03%]
西尼罗病毒忠实性调节宿主循环能力和适应能力
Haley S Caldwell,Kiet Ngo,Janice D Pata et al.
Haley S Caldwell et al.
The fidelity of flaviviruses is thought to be tightly regulated for optimal fitness within and between hosts. West Nile virus (WNV) high-fidelity (HiFi) mutations V793I and G806R within the RNA-dependent RNA polymerase, and low-fidelity (Lo...
Requirements for guinea pig cytomegalovirus tropism and antibody neutralization on placental amniotic sac cells [0.03%]
仓鼠巨细胞病毒对胎盘羊膜的嗜性及中和试验的要求
K Yeon Choi,Nadia S El-Hamdi,Alistair McGregor
K Yeon Choi
Congenital cytomegalovirus (cCMV) is a leading cause of birth defects. The guinea pig is the only small cCMV animal model. Guinea pig cytomegalovirus (GPCMV) encodes similar glycoprotein complexes to human CMV (HCMV) including gB and the gH...
Sequencing of serially passaged measles virus affirms its genomic stability and reveals a nonrandom distribution of consensus mutations [0.03%]
连续传代的麻疹病毒测序证实其基因组稳定性并揭示了共识突变的非随机分布
Mathias Felix Leber,Birgit Hoyler,Stefanie Prien et al.
Mathias Felix Leber et al.
Oncolytic virotherapy is an emerging treatment option for numerous cancers, with several virus families currently being evaluated in clinical trials. More specifically, vaccine-strain measles virus has arisen as a promising candidate for th...
Jakub Barylski,Andrew M Kropinski,Nabil-Fareed Alikhan et al.
Jakub Barylski et al.
Members of the family Herelleviridae are bacterial viruses infecting members of the phylum Firmicutes. The virions have myovirus morphology and virus genomes comprise a linear dsDNA of 125-170 kb. This is a summary of the International Comm...
Bombyx mori nucleopolyhedrovirus F-like protein Bm14 is a type I integral membrane protein that facilitates ODV attachment to the midgut epithelial cells [0.03%]
家蚕核型多角体病毒Bm14蛋白是一个I型跨膜蛋白，可促进OCV附着于中肠上皮细胞上
Weifan Xu,Xiangshuo Kong,Hang Liu et al.
Weifan Xu et al.
Our previous study showed that the Bombyx mori nucleopolyhedrovirus (BmNPV) F-like protein Bm14 is intrinsically related to the production of occlusion bodies, occlusion-derived virus (ODV) embedding and virulence in infected larvae. Howeve...