Akbar Dastjerdi,Camilla Benfield,David Everest et al.
Akbar Dastjerdi et al.
Astro- and kobuviruses infect both humans and animals. Here, we report on the disease history, detection and genomic characterization of novel astro- and kobuviruses from fatal diarrhoea of two juvenile grey squirrels. The virus particles h...
Turkey adenovirus 3, a siadenovirus, uses sialic acid on N-linked glycoproteins as a cellular receptor [0.03%]
利用N连接糖蛋白上的唾液酸作为细胞受体的si腺病毒3(火鸡)
Hassan M Mahsoub,Lijuan Yuan,F William Pierson
Hassan M Mahsoub
Turkey adenovirus 3 (TAdV-3) is the causative agent of an immune-mediated disease in turkeys, haemorrhagic enteritis, through targeting B lymphocytes. In the present study, we investigated the role of sialic acid in TAdV-3 entry and charact...
The dynamics of humoral immune responses following SARS-CoV-2 infection and the potential for reinfection [0.03%]
SARS-CoV-2感染后的体液免疫反应动力学及再感染的潜在可能
Paul Kellam,Wendy Barclay
Paul Kellam
SARS-CoV-2 is a novel coronavirus that is the causative agent of coronavirus infectious disease 2019 (COVID-19). As of 17 April 2020, it has infected 2 114 269 people, resulting in 145 144 deaths. The timing, magnitude and longevity of humo...
Exosomes promote caprine parainfluenza virus type 3 infection by inhibiting autophagy [0.03%]
exosomes通过抑制自噬促进_CAP感染
Li Mao,Panhong Liang,Wenliang Li et al.
Li Mao et al.
Caprine parainfluenza virus type 3 (CPIV3) is a novel important pathogen causing respiratory disease in goats, but the pathogenic mechanism is not clear yet. Evidence suggests that exosomes transfer biologically active molecules between cel...
Negligible effect of chicken cytokine IL-12 integration into recombinant fowlpox viruses expressing avian influenza virus neuraminidase N1 on host cellular immune responses [0.03%]
鸡细胞因子IL-12整合至表达禽流感病毒N1神经氨酸酶的重组番鸡痘病毒中对宿主细胞免疫应答的影响甚微
Nadzreeq Nor Majid,Abdul Rahman Omar,Abdul Razak Mariatulqabtiah
Nadzreeq Nor Majid
In comparison to the extensive characterization of haemagglutinin antibodies of avian influenza virus (AIV), the role of neuraminidase (NA) as an immunogen is less well understood. This study describes the construction and cellular response...
High prevalence and genomic characteristics of G6P[1] Bovine Rotavirus A in yak in China [0.03%]
中国牦牛中G6P[1]群B型轮状病毒的高流行与基因组特征分析
Nan Yan,Ran Li,Yuanwei Wang et al.
Nan Yan et al.
Yak is an iconic species of the Qinghai-Tibet Plateau, which is the world's highest plateau. Here, a total of 541 yak diarrhoeic samples were collected from 69 farms in four provinces in the Qinghai-Tibet Plateau from April 2015 to June 201...
Contribution of HDAC3 to transcriptional repression by the human papillomavirus 31 E8^E2 protein [0.03%]
人乳头瘤病毒31型E8^E2蛋白通过HDAC3发挥转录抑制作用
Marcel Dreer,Saskia Blondzik,Elke Straub et al.
Marcel Dreer et al.
Human papillomaviruses (HPV) such as HPV16 and HPV31 encode an E8^E2 protein that acts as a repressor of viral replication and transcription. E8^E2's repression activities are mediated via the interaction with host-cell NCoR (nuclear recept...
Characterization of a novel picornavirus isolated from moribund aquacultured clownfish [0.03%]
从养殖濒死小丑鱼中鉴定出一种新型的小核糖核酸病毒
Elizabeth C Scherbatskoy,Kuttichantran Subramaniam,Lowia Al-Hussinee et al.
Elizabeth C Scherbatskoy et al.
Over the last decade, a number of USA aquaculture facilities have experienced periodic mortality events of unknown aetiology in their clownfish (Amphiprion ocellaris). Clinical signs of affected individuals included lethargy, altered body c...
Functional analysis of the baculovirus per os infectivity factors 3 and 9 by imaging the interaction between fluorescently labelled virions and isolated midgut cells [0.03%]
荧光标记病毒与分离的中肠细胞相互作用成像分析杆状病毒经口感染因子3和9的功能
Bob Boogaard,Jan W M van Lent,Monique M van Oers
Bob Boogaard
Baculovirus occlusion-derived viruses (ODVs) contain ten known per os infectivity factors (PIFs). These PIFs are crucial for midgut infection of insect larvae and form, with the exception of PIF5, an ODV entry complex. Previously, R18-deque...
Using a mouse-adapted A/HK/01/68 influenza virus to analyse the impact of NS1 evolution in codons 196 and 231 on viral replication and virulence [0.03%]
利用适应小鼠的A/HK/01/68流感病毒分析NS1进化对病毒复制和毒力的影响
Sebastian Eiden,Ronald Dijkman,Roland Zell et al.
Sebastian Eiden et al.
Seasonal influenza viruses circulating between 1918 and 2009 harboured two prevalent genetic variations in the NS1 coding region. A glutamic acid (E)-to-lysine (K) exchange at position 196 was reported to diminish the capacity of NS1 to con...