Insights into SARS-CoV-2, the Coronavirus Underlying COVID-19: Recent Genomic Data and the Development of Reverse Genetics Systems [0.03%]
关于导致COVID-19疾病的新型冠状病毒SARS-CoV-2的最新见解：基于基因组数据及其反向遗传系统构建方面的新进展
Severino Jefferson Ribeiro da Silva,Renata Pessôa Germano Mendes,Caroline Targino Alves da Silva et al.
Severino Jefferson Ribeiro da Silva et al.
The emergence and rapid worldwide spread of a novel pandemic of acute respiratory disease - eventually named coronavirus disease 2019 (COVID-19) by the World Health Organization (WHO) - across the human population has raised great concerns....
Hepatitis B virus X protein stimulates cell growth by downregulating p16 levels via PA28γ-mediated proteasomal degradation [0.03%]
乙肝病毒X蛋白通过PA28γ介导的泛素-蛋白酶体途径降解p16基因产物来促进细胞生长
Sungkyung Cha,Kyung Lib Jang
Sungkyung Cha
Proteasomal activator 28 gamma (PA28γ), an essential constituent of the 20S proteasome responsible for ubiquitin-independent degradation of target proteins, is frequently overexpressed in hepatocellular carcinoma. Recently, we have reporte...
SARS-coronavirus-2 replication in Vero E6 cells: replication kinetics, rapid adaptation and cytopathology [0.03%]
SARS-CoV-2在Vero E6细胞中的复制：复制动力学、快速适应性和细胞病变效应
Natacha S Ogando,Tim J Dalebout,Jessika C Zevenhoven-Dobbe et al.
Natacha S Ogando et al.
The sudden emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) at the end of 2019 from the Chinese province of Hubei and its subsequent pandemic spread highlight the importance of understanding the full molecular detai...
Comparative Study
The Journal of general virology. 2020 Sep;101(9):925-940. DOI:10.1099/jgv.0.001453 2020
Genetic diversity of enterovirus G detected in faecal samples of wild boars in Japan: identification of novel genotypes carrying a papain-like cysteine protease sequence [0.03%]
日本野猪粪便样本中肠道病毒G的遗传多样性分析：识别出携带木瓜样半胱氨酸蛋白酶序列的新基因型
Ayaka Nagata,Yuya Sekiguchi,Toru Oi et al.
Ayaka Nagata et al.
The genetic diversity of enterovirus G (EV-G) was investigated in the wild-boar population in Japan. EV-G-specific reverse transcription PCR demonstrated 30 (37.5 %) positives out of 80 faecal samples. Of these, viral protein 1 (VP1) fragme...
Y-Box-Binding Protein 3 (YBX3) Restricts Influenza A Virus by Interacting with Viral Ribonucleoprotein Complex and Imparing its Function [0.03%]
Y框结合蛋白3(YBX3)通过与流感病毒核糖核蛋白复合体互作并抑制其功能限制流感病毒感染
Zhenqiao Qin,Xiao Qu,Lei Lei et al.
Zhenqiao Qin et al.
The influenza A virus (IAV) ribonucleoprotein (vRNP) complex consists of polymerase subunits, nucleoprotein (NP) and viral RNA and is responsible for RNA transcription and replication. Interactions between the vRNP complex and host factors ...
Retraction notice: Host protein CD63 promotes viral RNA replication by interacting with human astrovirus non-structural protein nsP1a/4 [0.03%]
撤稿通知：宿主蛋白CD63通过与人轮状病毒非结构蛋白nsP1a/4相互作用促进病毒RNA复制
The Microbiology Society
The Microbiology Society
Retraction of Publication
The Journal of general virology. 2020 Apr;101(4):453. DOI:10.1099/jgv.0.001372 2020
The stability of HIV-2 Vpx and Vpr proteins is regulated by the presence or absence of zinc-binding sites and poly-proline motifs with distinct roles [0.03%]
HIV-2 Vpx和Vpr蛋白的稳定性通过含锌结合位点及具有不同功能的聚脯氨酸基序的存在与否来调节
Kazunori Shimagaki,Ryoko Koga,Haruna Fujino et al.
Kazunori Shimagaki et al.
The Vpx and Vpr proteins of human immunodeficiency virus type 2 (HIV-2) are important for virus replication. Although these proteins are homologous, Vpx is expressed at much higher levels than Vpr. Previous studies demonstrated that this di...
First isolation and whole-genome characterization of a G9P[14] rotavirus strain from a diarrheic child in Egypt [0.03%]
埃及腹泻患儿中首次分离出的G9P[14]型轮状病毒毒株的全基因组特征分析
Ashraf Shoeib,Daniel E Velasquez Portocarrero,Yuhuan Wang et al.
Ashraf Shoeib et al.
An unusual group A rotavirus (RVA) strain (RVA/Human-tc/EGY/AS997/2012/G9[14]) was isolated for the first time in a faecal sample from a 6-month-old child who was hospitalized for treatment of acute gastroenteritis in Egypt in 2012. Whole-g...
Molecular simulation of SARS-CoV-2 spike protein binding to pangolin ACE2 or human ACE2 natural variants reveals altered susceptibility to infection [0.03%]
分子模拟揭示了SARS-CoV-2刺突蛋白与穿山甲ACE2或人类ACE2天然变异体的结合改变了感染的易感性
Jingfang Wang,Xintian Xu,Xinbo Zhou et al.
Jingfang Wang et al.
We constructed complex models of SARS-CoV-2 spike protein binding to pangolin or human ACE2, the receptor for virus transmission, and estimated the binding free energy changes using molecular dynamics simulation. SARS-CoV-2 can bind to both...
Jan F Kreuze,Anna Maria Vaira,Wulf Menzel et al.
Jan F Kreuze et al.
The family Alphaflexiviridae includes viruses with flexuous filamentous virions that are 470-800 nm in length and 12-13 nm in diameter. Alphaflexiviruses have a single-stranded, positive-sense RNA genome of 5.5-9 kb. They infect plants and ...