Emmanuelle Neumann,Takeru Kawasaki,Grégory Effantin et al.
Emmanuelle Neumann et al.
Jumbo phages are bacteriophages that carry more than 200 kbp of DNA. In this study we characterized two jumbo phages (ΦRSL2 and ΦXacN1) and one semi-jumbo phage (ΦRP13) at the structural level by cryo-electron microscopy. Focusing on the...
Aura R Garrison,Sergey V Alkhovsky Альховский Сергей Владимирович,Tatjana Avšič-Županc et al.
Aura R Garrison et al.
Members of the family Nairoviridae produce enveloped virions with three single-stranded RNA segments comprising 17.1 to 22.8 kb in total. These viruses are maintained in arthropods and transmitted by ticks to mammals or birds. Crimean-Congo...
Sari Mäntynen,Elina Laanto,Lotta-Riina Sundberg et al.
Sari Mäntynen et al.
Finnlakeviridae is a family of icosahedral, internal membrane-containing bacterial viruses with circular, single-stranded DNA genomes. The family includes the genus, Finnlakevirus, with the species, Flavobacterium virus FLiP. Flavobacterium...
SARS-CoV-2 growth, furin-cleavage-site adaptation and neutralization using serum from acutely infected hospitalized COVID-19 patients [0.03%]
SARS-CoV-2的生长，四肽碱性氨基酸蛋白酶裂解位点的适应以及使用急性感染住院COVID-19患者的血清进行中和研究
William B Klimstra,Natasha L Tilston-Lunel,Sham Nambulli et al.
William B Klimstra et al.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19), emerged at the end of 2019 and by mid-June 2020 the virus had spread to at least 215 countries, caused more than 8 000...
Use of a small DNA virus model to investigate mechanisms of CpG dinucleotide-induced attenuation of virus replication [0.03%]
使用小型DNA病毒模型来研究CpG双核苷酸诱导的病毒复制减弱机制
Lisa Loew,Niluka Goonawardane,Jeremy Ratcliff et al.
Lisa Loew et al.
Suppression of the CpG dinucleotide is widespread in RNA viruses infecting vertebrates and plants, and in the genomes of retroviruses and small mammalian DNA viruses. The functional basis for CpG suppression in the latter was investigated t...
Rules governing genetic exchanges among viral types from different Enterovirus A clusters [0.03%]
不同A簇肠道病毒类型之间基因交换的规则
Min Wang,Liuyao Zhu,Jun Fan et al.
Min Wang et al.
The species Enterovirus A (EV-A) consists of two conventional clusters and one unconventional cluster. At present, sequence analysis shows no evidence of recombination between conventional and unconventional EV-A types. However, the factors...
Viral interactions with non-homologous end-joining: a game of hide-and-seek [0.03%]
病毒与非同源末端连接的相互作用：一场捉迷藏游戏
Dayana B Hristova,Katharina B Lauer,Brian J Ferguson
Dayana B Hristova
There are extensive interactions between viruses and the host DNA damage response (DDR) machinery. The outcome of these interactions includes not only direct effects on viral nucleic acids and genome replication, but also the activation of ...
Recombinant subtype A and B human respiratory syncytial virus clinical isolates co-infect the respiratory tract of cotton rats [0.03%]
人呼吸道合胞病毒A亚型和B亚型基因重组嵌合体在兔鼠中的共感染
Linda J Rennick,Sham Nambulli,Ken Lemon et al.
Linda J Rennick et al.
Human respiratory syncytial virus (HRSV) is an important respiratory pathogen causing a spectrum of illness, from common cold-like symptoms, to bronchiolitis and pneumonia requiring hospitalization in infants, the immunocompromised and the ...
Multiple novel non-canonically transcribed sub-genomic mRNAs produced by avian coronavirus infectious bronchitis virus [0.03%]
由禽冠状病毒引起的传染性支气管炎病毒的多种新非规范亚基因组mRNA产物
Sarah Keep,Michael S Oade,Filip Lidzbarski-Silvestre et al.
Sarah Keep et al.
Coronavirus sub-genomic mRNA (sgmRNA) synthesis occurs via a process of discontinuous transcription involving complementary transcription regulatory sequences (TRSs), one (TRS-L) encompassing the leader sequence of the 5' untranslated regio...
Characterization of mammalian orthoreoviruses isolated from faeces of pigs in Zambia [0.03%]
赞比亚猪粪便中哺乳动物正重链 Reo病毒的分离及鉴定
Hayato Harima,Michihito Sasaki,Masahiro Kajihara et al.
Hayato Harima et al.
Mammalian orthoreovirus (MRV) has been identified in humans, livestock and wild animals; this wide host range allows individual MRV to transmit into multiple species. Although several interspecies transmission and genetic reassortment event...