Role of γδ T cells in turkey herpesvirus vaccine protection against Marek's disease virus [0.03%]
γδT细胞在火鸡疱疹病毒疫苗对马立克氏病病毒感染的保护作用中的功能研究
Mohammad A Sabsabi,Ahmed Kheimar,Dominik von La Roche et al.
Mohammad A Sabsabi et al.
γδ T cells are a highly abundant lymphocyte subset in chickens and play key roles in early immune responses to infection. It has been recently shown that γδ T cells restrict Marek's disease virus (MDV) pathogenesis; however, it remained...
Australian strains of the avian coronavirus infectious bronchitis virus predominantly target the respiratory tract rather than the kidneys in specific-pathogen-free chickens [0.03%]
澳大利亚产禽传染性支气管炎病毒毒株主要攻击无特定病原鸡的呼吸系统而非肾脏
Jose A Quinteros,Panayiotis Loukopoulos,Amir H Noormohammadi et al.
Jose A Quinteros et al.
Coronaviruses evolve rapidly, with recombination and mutation fostering the emergence of variant strains. The avian coronavirus infectious bronchitis virus (IBV) is an important poultry pathogen and a valuable natural model for studying cor...
Genetic diversity and evolutionary dynamics of Senecavirus A in Brazil [0.03%]
巴西 senecavirus a 的遗传多样性及进化动态
Leonardo Clasen Ribeiro,Salman Latif Butt,Ruchi Rani et al.
Leonardo Clasen Ribeiro et al.
Senecavirus A (SVA) is a picornavirus that was first isolated in the USA in 2002; however, there is evidence that the virus was circulating in swine herds since 1988. Despite frequent reports of vesicular disease outbreaks caused by SVA inf...
A replication-competent deltavirus from the marsupial fat-tailed dunnart Sminthopsis crassicaudata [0.03%]
取脂尾袋貂Sminthopsis crassicaudata的复制型德尔塔病毒
Zoé Denis,Valérie Courgnaud,Marcos de la Peña et al.
Zoé Denis et al.
Deltaviruses are circular, negative-sense RNA agents that replicate autonomously but depend on heterologous envelope glycoproteins for spread. Only partial sequences of deltaviruses had been reported from marsupials. By reanalysing public m...
Nucleolar targeting of lyssavirus P-protein is isoform- and phylogroup-specific [0.03%]
裂谷热病毒P蛋白的核糖体定位具有异构体和系统发育型特异性
Gregory W Moseley,Yilin Zhang,Cassandra T David et al.
Gregory W Moseley et al.
The nucleolus is a multifunctional hub and a common target of viral proteins, yet its role in infections by cytoplasmically replicating RNA viruses remains poorly defined. In rabies virus (RABV), the phosphoprotein (P-protein) isoform P3 lo...
Atkinsonella hypoxylon virus capsid structure highlights the diversity of capsid proteins among the Partitiviridae [0.03%]
Atkinsonella hypoxylon病毒的衣壳结构突显了Partitiviridae家族中衣壳蛋白的多样性
Micol Venturi,Matthew Calthorpe-Byrne,Beate Aftret et al.
Micol Venturi et al.
Atkinsonella hypoxylon virus (AhV) is a fungi-infecting betapartitivirus and the typical member of the Partitiviridae, a family of persistent viruses that infect a broad range of organisms. Partitiviruses have been largely overlooked follow...
The cellular activating protein-1 cFos regulates influenza A virus replication [0.03%]
活化蛋白1家族成员c-Fos调控甲型流感病毒复制
Antoine Gerodez,François E Dufrasne,Olivier Denis et al.
Antoine Gerodez et al.
Previous research has demonstrated that influenza A virus (IAV) infection activates activating protein-1 (AP-1) transcription factors as part of the antiviral response. In this study, we identified cFos as the most upregulated AP-1 transcri...
Optimizing delivery of an anti-cytomegalovirus inhibitory peptide using a cell-penetrating peptide [0.03%]
利用穿膜肽优化细胞内抗巨细胞病毒抑制性肽的递送
Komal Beeton,Jacob P Haskell,Dipanwita Mitra et al.
Komal Beeton et al.
Cytomegalovirus (CMV) is a beta herpesvirus that persists quiescently in healthy individuals but causes severe disease in immunocompromised patients and congenitally infected newborns. Side effects posed by the currently available antiviral...
Antigenicity of key hepatitis C virus E1E2 glycoprotein neutralizing sites is genotype independent [0.03%]
关键的丙型肝炎病毒E1E2糖蛋白反应中和位点的抗原性与基因型无关
Jessica L Mimms,Ariadne Sinnis-Bourozikas,Nathaniel R Felbinger et al.
Jessica L Mimms et al.
The development of an effective prophylactic hepatitis C virus (HCV) vaccine is a priority to achieve global elimination of the virus. Accurate assessment of the neutralizing breadth of antibodies induced by vaccines and a clear understandi...
Paolo Ribeca,Patricia Dewar,Michelle L McNab et al.
Paolo Ribeca et al.
Ovine herpesvirus 1 (OvHV-1) was first identified over 50 years ago in sheep with ovine pulmonary adenocarcinoma (OPA). An aetiological role in OPA was later ruled out and OvHV-1 was found to be a common infection in sheep in several countr...