Hendra virus genotypes 1 and 2 differ in V protein-mediated immune evasion [0.03%]
亨德拉病毒基因型1和基因型2的V蛋白介导的免疫逃避机制不同
Melanie N Tripp,Stephen M Rawlinson,Sarah J Edwards et al.
Melanie N Tripp et al.
Hendra virus (HeV) is a highly pathogenic virus endemic to Australia that causes lethal infections in horses and humans following spillover from bat reservoirs. There are two known genotypes: genotype 1 and 2 (HeV-g1 and HeV-g2). Both have ...
Structural insights into the nuclear import of ovine gammaherpesvirus 2 ORF73 LANA homologue [0.03%]
羊γ疱疹病毒2型ORF73 LANA同源物核输入的结构见解
Babu Kanti Nath,Renate H M Schwab,Crystall M D Swarbrick et al.
Babu Kanti Nath et al.
Ovine gammaherpesviruses 2 (OvGHV2), a member of the Macavirus genus within the Orthoherpesviridae family, causes lymphoproliferative diseases in susceptible species, most notably sheep-associated malignant catarrhal fever. Research on OvGH...
Apoorva Prabhu,Christian Rinke
Apoorva Prabhu
The family Krittikaviridae includes dsDNA viruses associated with the marine archaeal lineage Poseidoniales. These viruses have been identified through metagenomic analysis of brackish estuarine samples and are closely related to other 'mag...
Identification of the nucleolar localization signal in Autographa californica multiple nucleopolyhedrovirus multifunctional protein Ac16 [0.03%]
烟草多角体病毒多功能蛋白Ac16核仁定位信号的鉴定
Guoqing Chen,Yihong Wu,Jing Yang et al.
Guoqing Chen et al.
Autographa californica multiple nucleopolyhedrovirus (AcMNPV) Ac16 (BV/ODV-E26) is a multifunctional protein found exclusively in group I NPV genomes. Here, we report a novel role for Ac16 in nucleolar localization. Using protein truncation...
Sexual transmission of hepatitis E virus via vaginal and rectal routes in a rabbit model [0.03%]
经阴道和肛交传播戊型肝炎病毒的兔模型研究
Manyu Li,Wenjun Wan,Zeyu Song et al.
Manyu Li et al.
Hepatitis E virus (HEV) is a major cause of acute hepatitis worldwide. While faecal-oral transmission is well-established, the potential for sexual transmission remains unclear. This study aimed to investigate whether HEV can be transmitted...
Local citrus sudden death-associated virus infection in Nicotiana benthamiana induces chloroplast structural changes and HR-like responses that do not restrict systemic virus movement [0.03%]
橘柑本地猝死综合症相关病毒（CLSDVa）对弯管花烟草的感染导致类囊体结构改变和类似HR反应但不影响系统移动性
Sayuri Iwasaki,Dennis van Oevelen,Alba Pérez-Sánchez et al.
Sayuri Iwasaki et al.
The use of infectious clones to establish virus infections in well-established model plants has allowed us to greatly advance our understanding of virus-host interactions, providing controlled systems to study viruses that naturally infect ...
Integrating metagenomics and metatranscriptomics into Orthoflavivirus diagnosis: a transformative approach for clinical virology [0.03%]
元基因组学和元转录组学在Orthoflavivirus诊断中的整合：临床病毒学的变革性方法
Md Eram Hosen,Paul F Horwood,Subir Sarker
Md Eram Hosen
Diagnostic inaccuracies are a major yet often overlooked threat to global health, leading to delayed treatment, preventable harm and systemic gaps in disease control. Among the most affected domains are Orthoflavivirus infections, which pos...
Simona Kraberger,Tanja Opriessnig,Fabrizio Maggi et al.
Simona Kraberger et al.
The family Anelloviridae includes viruses with circular, negative-sense, ssDNA genomes of 1.7-3.9 kb. Anelloviruses form non-enveloped icosahedral virions constructed of the ORF1 protein, which adopts the single jelly-roll structural fold. ...
SARS-CoV-2 Nsp15 facilitates immune evasion and viral replication by limiting multiple host innate immune pathways, including cGAS-STING [0.03%]
SARS-CoV-2 Nsp15通过限制多个宿主天然免疫途径（包括cGAS-STING）来促进免疫逃逸和病毒复制
Hsin-Ping Chiu,Yao Yu Yeo,Tsoi Ying Lai et al.
Hsin-Ping Chiu et al.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) nonstructural protein 15 (Nsp15) is a conserved uridine-specific endoribonuclease (EndoU) and is implicated in innate immune evasion, yet its precise molecular mechanism remains i...
Bovine respiratory syncytial virus utilizes the human insulin-like growth factor 1 receptor in the late stages of infection [0.03%]
牛呼吸道合胞病毒利用人类胰岛素样生长因子1受体在感染的晚期阶段发挥作用
Sodbayasgalan Amarbayasgalan,Tatsuki Takahashi,Yoshiro Sugiura et al.
Sodbayasgalan Amarbayasgalan et al.
Bovine respiratory syncytial virus (BRSV) is a major viral pathogen associated with the bovine respiratory disease complex, which is a leading cause of morbidity, mortality and economic loss in the cattle industry worldwide. Clinical infect...