Kenji K Kojima
Kenji K Kojima
Eukaryotic reverse transcriptase genes are mostly incorporated into viruses or transposons. Among the six reported families of reverse-transcribing viruses, three families (Metaviridae/Gypsy, Belpaoviridae/BEL and Pseudoviridae/Copia) have ...
Tracking early cytological changes following expression of NSm and N proteins from tomato spotted wilt virus field isolates [0.03%]
田间番茄斑点萎蔫病毒NSm和N蛋白表达后的早期细胞学变化监测
Alexandra C Rios,Abdelaal H A Shehata,Amanda Strayer-Scherer et al.
Alexandra C Rios et al.
Tomato spotted wilt virus (TSWV) is a major yield-limiting pathogen of peanut in the southeastern USA. To assess viral variability, field isolates were collected from symptomatic peanut plants at three locations in Alabama. Sequence analysi...
Conserved and distinct expression of circular RNAs in commercially used Marek's disease vaccine viruses [0.03%]
用于商业化的马立克氏病疫苗病毒中外显子环状RNA的表达与鉴定
Camille Ponsard,Alexis S Chasseur,Pierre Lombard et al.
Camille Ponsard et al.
Circular RNAs (circRNAs) are covalently closed RNA molecules, supporting a wide diversity of functions. While aberrant circRNA expression stands as a recognized hallmark of cancer development, our attention has turned to investigating their...
SARS-CoV-2 infection of substantia nigra pars compacta induces expression of miR-330-5p at 10 days post-infection [0.03%]
感染后的第10天，SARS-CoV-2感染致密黑质会诱导miR-330-5p的表达
Bishwa R Pokharel,Niska Majumdar,Frank Williams et al.
Bishwa R Pokharel et al.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been linked to several neurological symptoms in coronavirus disease 2019 (COVID-19) patients; however, the molecular mechanisms underlying virus-induced neuroinflammation are ...
Evelien M Adriaenssens,Ryan Cook,Valerian Dolja et al.
Evelien M Adriaenssens et al.
The realm Duplodnaviria includes viruses of archaea, bacteria and eukaryotes, with linear dsDNA genomes. Duplodnavirians share a distinct morphogenetic module of four hallmark genes encoding the HK97-fold major capsid protein, a genome pack...
A Japanese encephalitis virus biological clone with an E gene point mutation exhibits in vitro and in vivo attenuation of neurovirulence [0.03%]
乙基因点突变的 japanese encephalitis 病毒生物学克隆株毒力减弱
Shu Pin Yu,Kien Chai Ong,Soon Hao Tan et al.
Shu Pin Yu et al.
The Japanese encephalitis virus (JEV), a leading cause of viral encephalitis, exists as similar but non-identical biological clones whose genomic variations/mutations may determine neurovirulence. Two biological clones purified from a brain...
Robust polyfunctional CD8+ and CD4+ T cell responses in HLA-A*0201/DR1 transgenic mice following vaccination with modified vaccinia virus Ankara-based vaccines delivering Lassa virus glycoprotein or nucleoprotein [0.03%]
重组痘苗病毒安卡拉毒株疫苗递送拉沙病毒糖蛋白或核蛋白后HLA-A*0201 / DR1转基因小鼠产生稳健多功能CD8 +和CD4+ T细胞反应
Alina Tscherne,Georgia Kalodimou,Sylvia Jany et al.
Alina Tscherne et al.
Lassa virus (LASV) is circulating in rodents in several countries in West Africa and is the causative agent of the zoonotic disease Lassa fever. Several vaccine candidates have been successfully tested in preclinical and clinical research, ...
Investigating factors driving shifts in subtype dominance within H5Nx clade 2.3.4.4b high pathogenicity avian influenza viruses [0.03%]
探究H5Nx型2.3.4.4b亚系高致病性禽流感病毒谱系优势转换的驱动因素
Elizabeth Billington,Cecilia Di Genova,Caroline J Warren et al.
Elizabeth Billington et al.
H5Nx clade 2.3.4.4b high pathogenicity avian influenza viruses (HPAIVs) have decimated wild bird and poultry populations globally since the autumn of 2020. In the UK and in continental Europe, the H5N8 subtype predominated during the first ...
Mechanistic insights into Nipah virus 5' UTR functionality reveal an antiviral target [0.03%]
尼帕病毒5'-UTR功能机制的见解揭示了一个抗病毒靶点
Lishi Liu,Chaohu Pan,Zhen Chen et al.
Lishi Liu et al.
The highly pathogenic Nipah virus (NiV), a World Health Organization priority pathogen with pandemic potential, remains a critical public health threat due to its capacity to cause fatal encephalitis and respiratory disease. Despite its 199...
A direct RNA-seq-based EBV latency transcriptome offers insights into the biogenesis of EBV gene products [0.03%]
基于直接RNA测序的EB病毒潜伏转录组为EB病毒基因产物的生物发生提供了新的见解
Aaron Mamane-Logsdon,Isabelle Zane,June See Chong et al.
Aaron Mamane-Logsdon et al.
Epstein-Barr virus (EBV) ubiquitously infects humans, establishing lifelong persistence in B cells. In vitro, EBV-infected B cells can establish a lymphoblastoid cell line (LCL). EBV's transcripts in LCLs (latency III) produce six nuclear p...