Influenza virus infection as well as immunization with DNA encoding haemagglutinin protein induces potent antibody-dependent phagocytosis (ADP) and monocyte infection-enhancing responses in macaques [0.03%]
流感病毒感康以及用编码血凝素蛋白的DNA免疫可诱导恒河猴产生有效的抗体依赖性细胞吞噬作用(ADP)和单核细胞感染增强反应
Gerrit Koopman,Daniella Mortier,Samira Michels et al.
Gerrit Koopman et al.
Antibodies directed against the conserved regions within the influenza A haemagglutinin (HA) protein are detected at low frequency in humans. These antibodies display a broad reactivity against divergent influenza virus strains and could po...
Upregulation of CHOP participates in caspase activation and virus release in human astrovirus-infected cells [0.03%]
CHOP上调参与人类astro病毒阳性的细胞凋亡和病毒释放过程
Tomoyasu Isobe,Shoichiro Tange,Hidetaka Tasaki et al.
Tomoyasu Isobe et al.
Human astroviruses (HAstVs), non-enveloped RNA viruses with positive-sense RNA genomes, are an important cause of acute gastroenteritis in young children, although the processes that produce infectious virions are not clearly defined. To tr...
IRF4 promotes Epstein-Barr virus activation in Burkitt's lymphoma cells [0.03%]
IRF4促进Burkitt淋巴瘤细胞中EB病毒的活化
Ying Gao,Liu Wang,Zhangmengxue Lei et al.
Ying Gao et al.
Epstein-Barr virus (EBV) establishes a life-long latency in memory B cells, whereas plasma cell differentiation is linked to EBV lytic reactivation from latently infected B cells. EBV lytic replication is mediated by the two immediate-early...
Characterization of Fowlpox virus in chickens and bird-biting mosquitoes: a molecular approach to investigating Avipoxvirus transmission [0.03%]
鸡和吸鸟蚊中火鸡疱疹病毒的特征研究：分子方法探究Avipoxvirus传播
Gladys Yeo,Yifan Wang,Shin Min Chong et al.
Gladys Yeo et al.
Avian pox is a highly contagious avian disease, yet relatively little is known about the epidemiology and transmission of Avipoxviruses. Using a molecular approach, we report evidence for a potential link between birds and field-caught mosq...
Detection of antisense protein (ASP) RNA transcripts in individuals infected with human immunodeficiency virus type 1 (HIV-1) [0.03%]
人类免疫缺陷病毒(HIV-1)感染者的反义蛋白(ASP)RNA转录的检测
Antonio Mancarella,Francesco A Procopio,Tilmann Achsel et al.
Antonio Mancarella et al.
The detection of antisense RNA is hampered by reverse transcription (RT) non-specific priming, due to the ability of RNA secondary structures to prime RT in the absence of specific primers. The detection of antisense RNA by conventional RT-...
A recombinant canine distemper virus expressing interleukin-7 enhances humoral immunity [0.03%]
表达白细胞介素-7的重组犬瘟病毒能增强体液免疫反应
Chen Chen,Ming Zhou,Xiao-Geng Yan et al.
Chen Chen et al.
Canine distemper (CD) causes gastrointestinal and respiratory and/or neurological signs and results in high morbidity and mortality, remaining a threat to carnivores around the world. Live-attenuated vaccines have been widely used to reduce...
In vitro and in vivo roles of sphingosine kinase 2 during dengue virus infection [0.03%]
唾液酸辛二酮在登革热病毒感染的体内外作用
Wisam H Al-Shujairi,Jennifer N Clarke,Lorena T Davies et al.
Wisam H Al-Shujairi et al.
There is growing evidence of the influence of sphingosine kinase (SK) enzymes on viral infection. Here, the role of sphingosine kinase 2 (SK2), an isoform of SK prominent in the brain, was defined during dengue virus (DENV) infection. Chemi...
A novel species of RNA virus associated with root lesion nematode Pratylenchus penetrans [0.03%]
与根病变线虫Pratylenchus penetrans相关的新型RNA病毒种属
Paulo Vieira,Lev G Nemchinov
Paulo Vieira
The root lesion nematode Pratylenchus penetrans is a migratory species that attacks a broad range of plants. While analysing transcriptomic datasets of P. penetrans, we have identified a full-length genome of an unknown positive-sense singl...
Evaluation of 2012 US EHDV-2 outbreak isolates for genetic determinants of cattle infection [0.03%]
美国2012年EHDV-2爆发毒株感染牛的遗传决定因子评估
Erin E Schirtzinger,Dane C Jasperson,Mark G Ruder et al.
Erin E Schirtzinger et al.
Following a summer of severe drought and abnormally high temperatures, a major outbreak of EHDV occurred during 2012 in the USA. Although EHDV-1, -2 and -6 were isolated, EHDV-2 was the predominant virus serotype detected during the outbrea...
A low-passage insect-cell isolate of bluetongue virus uses a macropinocytosis-like entry pathway to infect natural target cells derived from the bovine host [0.03%]
一种低通透性昆虫细胞分离的蓝舌病毒使用类似巨胞饮的方式感染来源于牛宿主的天然靶细胞
Lisa M Stevens,Katy Moffat,Lyndsay Cooke et al.
Lisa M Stevens et al.
Bluetongue virus (BTV) causes an economically important disease in domestic and wildlife ruminants and is transmitted by Culicoides biting midges. In ruminants, BTV has a wide cell tropism that includes endothelial cells of vascular and lym...