Extensive hidden prophage diversity in Enterobacter species reveals host specificity and local distribution [0.03%]
肠杆菌属物种中广泛的噬菌体基因组多样性揭示了宿主特异性和局部分布特征
Danna Paola Bours-Lugo,Juan Manuel Hurtado-Ramírez,Armando Hernández-Mendoza et al.
Danna Paola Bours-Lugo et al.
Bacteriophages are key drivers of bacterial evolution, particularly through their integration as prophages within host genomes. However, the diversity and host specificity of prophages in relevant pathogens such as Enterobacter species rema...
Linda Huijboom,Marcel Tempelaars,Sjef Boeren et al.
Linda Huijboom et al.
This study describes an alternative role of the general stress response (GSR) regulated by Sigma B, via the two-component system RsbKY, which is methylated via RsbM, in motility regulation for the peritrichously flagellated, motile, foodbor...
Stephen Spiro,David J Richardson
Stephen Spiro
Paracoccus denitrificans is a metabolically versatile alphaproteobacterium first isolated in 1910 by Martinus Beijerinck. Similarities between the aerobic respiratory chain and membrane composition of P. denitrificans and those of eukaryoti...
Variations in carbapenem resistance associated with the VIM-1 metallo-β-lactamase across the Enterobacterales [0.03%]
产VIM-1金属β内酰胺酶肠杆菌目碳青霉烯耐药性的差异性分析
Mia Rondinelli,Sabhjeet Kaur,Owen A Ledwell et al.
Mia Rondinelli et al.
The VIM-1 metallo-β-lactamase enzyme, encoded within class 1 integrons, is found in Gram-negative clinical isolates worldwide and has been linked to outbreaks of bacterial pathogens in nosocomial settings. Six vim-1+ clinical isolates, fro...
Improving a Tn7-based luciferase reporter system for promoter activity studies [0.03%]
改进Tn7基荧光素酶报告系统促进启动子活性研究
Brenno Wendler Miranda,Cristina Elisa Alvarez-Martinez
Brenno Wendler Miranda
Single-copy chromosomal integration systems are essential tools for stable gene expression in bacteria, minimizing variability associated with plasmid-based systems. The Tn7 transposon-based system is widely used for this purpose, and one i...
Depletion of the Candida albicans TLO gene family reveals a requirement for alpha TLO genes for wild-type virulence [0.03%]
卡帕氏肺孢子菌TLO基因家族的耗竭揭示了α-TLO基因对野生毒力的必要性
James OConnor-Moneley,Theresa Lange,Peter R Flanagan et al.
James OConnor-Moneley et al.
Candida albicans uniquely possesses an expanded family of genes (the TLO gene family) that encodes 10-15 paralogues of the Med2 component of the transcriptional regulator Mediator. Previous studies have shown that TLO null mutants are unabl...
Hurdles to horizontal gene transfer: species-specific effects of synonymous variation and plasmid copy number determine antibiotic resistance phenotype [0.03%]
水平基因转移的障碍:同义变异和质粒拷贝数的物种特异性效应决定抗生素抗性表型
Michael Finnegan,Caroline J Rose,Jeanne Hamet et al.
Michael Finnegan et al.
Could codon composition condition the immediate success and the orientation of horizontal gene transfer? Horizontal gene transfer represents a change in the genome of expression of the transferred gene, and experimental evidence has accumul...
Phenylacetic acid mediates Acinetobacter baumannii entry into a viable but non-culturable state [0.03%]
苯乙酸介导鲍曼不动杆菌进入活性但非培养状态
Lyuboslava G Harkova,Rubén de Dios,Ronan R McCarthy
Lyuboslava G Harkova
Desiccation tolerance is central to the pathogenic success of the opportunistic pathogen Acinetobacter baumannii, allowing its survival on hospital surfaces in the absence of water and nutrients for months at a time, compromising surface de...
Azotobacter vinelandii gene fitness following carbon shift from sucrose to acetate, succinate and glycerol [0.03%]
Azotobacter vinelandii 碳源由蔗糖转变为乙酸、琥珀酸和甘油后的基因适应度变化
Carolann M Knutson,Brett M Barney
Carolann M Knutson
Nitrogen-fixing microbes are a primary contributor of this important nutrient to the global nitrogen cycle. Biological nitrogen fixation (BNF) through the enzyme nitrogenase requires extensive energy that in whole cells is generally studied...
Lack of a putative intrinsically disordered protein anchored to the sporangiospore cell wall causes fragile sporangium formation in Actinoplanes missouriensis [0.03%]
放线菌细胞壁缺乏一种假定的内在无序蛋白质导致分生孢子囊壁形成脆弱
Zhuwen Tan,Takeaki Tezuka,Yasuo Ohnishi
Zhuwen Tan
The filamentous actinomycete Actinoplanes missouriensis develops terminal sporangia on substrate mycelia via short sporangiophores. Each sporangium, surrounded by an outer envelope, contains a few hundred spores encapsulated by the sporangi...