Zinc tolerance through glutathione import strikes a fine balance between protection and damage in Streptococcus mutans [0.03%]
通过谷胱甘肽输入平衡耐锌保护与损伤之间的关系——以变异链球菌为例
Miranda C Carter,Edroyal Womack,Malak Khatib et al.
Miranda C Carter et al.
Recently, our group showed that the dental pathogen Streptococcus mutans is inherently more tolerant to high zinc stress than other streptococci, a phenotype associated with the presence of a P-type ATPase exporter named ZccE, virtually uni...
Microbial Primer: Bayesian learning of traits from microbial time series data [0.03%]
基于微生物时间序列数据的性状贝叶斯学习
Raunak Dey,Robert Beach,Kennedi M Hambrick et al.
Raunak Dey et al.
Mathematical models are increasingly used to infer traits, interactions and functional dynamics of microbial systems. One common example is a rate-based ordinary differential equation model parameterized with microbial traits. However, fitt...
Microbe Profile: Planctopirus limnophila: the platypus of microbiology [0.03%]
微生物档案：Planctopirus limnophila：微生物学中的鸭嘴兽
Elena Rivas-Marin,Damien P Devos
Elena Rivas-Marin
Interactions at the Streptomyces - animal interface: ecology, defence and disease [0.03%]
放线菌-动物界面的相互作用：生态、防御与疾病
Ainsley D M Beaton,James T Croxford,Alejandra C Díaz de Aguinaga et al.
Ainsley D M Beaton et al.
Streptomyces are filamentous, spore-forming members of the Actinomycetota, renowned for their capacity to produce chemically diverse, specialized metabolites with medically important properties. Traditionally, Streptomyces have been viewed ...
Elena Garcia-Perez,Louis Perrin,Jacob G Malone et al.
Elena Garcia-Perez et al.
Rhizobacteria play a central role in supporting plant growth, contributing to nutrient acquisition, stress tolerance and disease suppression. Harnessing and improving rhizosphere microbial communities therefore represents a promising avenue...
Saturated fatty acids enhance daptomycin activity in a Fak-dependent manner in enterococci [0.03%]
饱和脂肪酸通过Fak依赖性方式增强达托霉素对肠球菌的作用
Sudan Maharjan,Troy A Getty,Quiana Dickens et al.
Sudan Maharjan et al.
Antibiotic resistance of Gram-positive bacteria poses a major clinical challenge. Daptomycin, a lipopeptide antibiotic, is a treatment option for drug-resistant organisms. However, there have been clinical reports of daptomycin resistance a...
Sphingosine synergizes with polymyxin antibiotics against Pseudomonas aeruginosa and Klebsiella pneumoniae [0.03%]
鞘氨醇与多粘菌素抗生素协同作用以对抗绿脓杆菌和肺炎克雷伯氏菌
Jacob R Mackinder,Meghan Quinlan,Matthew J Wargo
Jacob R Mackinder
Antimicrobial resistance is an increasing threat to global health. However, there is a limited set of antibiotics that are effective against drug-resistant Gram-negative bacteria like Pseudomonas aeruginosa. One strategy to enhance the effi...
Cemile Selin Aksoy
Cemile Selin Aksoy
Antibiotic resistance remains one of the most pressing challenges in modern microbiology. Decades of research have focused on identifying resistance genes and molecular mechanisms in opportunistic pathogens. Yet bacterial survival under ant...
Host prenylation promotes membrane association of the Salmonella effector GtgE during infection [0.03%]
宿主的异戊二烯化促进沙门氏菌效应蛋白GtgE在感染过程中的膜结合作用
Natalia Cattelan,Hongjiao Yu,Kornelia Przybyszewska et al.
Natalia Cattelan et al.
The Rab32 antimicrobial pathway restricts Salmonella Typhi replication in murine macrophages. The broad-host pathogen Salmonella Typhimurium has evolved a solution to disrupt this pathway via effector proteins, including GtgE. The presence ...
Vittorio Venturi,Livia Leoni
Vittorio Venturi