Grace Kocks,Fahima Begum,Peter Ceuppens et al.
Grace Kocks et al.
The 38th annual meeting of the Industrial Genotoxicology Group (IGG) was held at Lhasa Limited, Leeds, UK on 2 December 2025, and focussed on the assessment of biological relevance in genotoxicity testing and the appropriate use of historic...
Antioxidant and Geno-protective Effects of Naturally Occurring Delphinidin Glycosides [0.03%]
天然存在的飞燕草素糖苷的抗氧化和基因保护作用
Giorgia Martelli,Carima Lörch,Naji Said Aboud Hadi et al.
Giorgia Martelli et al.
Anthocyanins are flavonoid pigments responsible for red, blue, and purple coloration in plants and play a protective role against abiotic stress through reactive oxygen species scavenging. They are abundant in the human diet, with berries s...
Kirsty Meldrum,Michael J Burgum,Shareen H Doak et al.
Kirsty Meldrum et al.
The indoor environment changes based on a variety of different factors, therefore changing the genotoxic potential of that environment. Despite the associations of exposure to outdoor air pollution and links to health impacts, enough is not...
Unveiling the Genotoxic Safety and Antioxidant-Mediated DNA Protective Mechanisms of Triammonium Citrate: An Integrated In Vitro and In Silico Approach [0.03%]
三水合柠檬酸铵的基因毒安全性和抗氧化介导的DNA保护机制：一种整合的体外和分子对接模拟研究方法
Emin Öztürk,Hasan Basri İla
Emin Öztürk
Triammonium citrate (TAC) is a citrate salt widely utilized in diverse industrial and dietary applications, leading to widespread human exposure. While related citrate salts have established safety profiles, the specific genotoxic potential...
Nutritional maternal factors affect the frequency of DNA damage in newborns [0.03%]
营养性母体因素影响新生儿DNA损伤频率
Anny Cristine Araújo,Fabrícia de Medeiros Morais,Daline Fernandes de Souza Araújo et al.
Anny Cristine Araújo et al.
Maternal nutrition can influence genetic health during pregnancy, increasing the risk of DNA damage in both the mother and fetus. This study investigated the effect of maternal nutritional factors on DNA damage biomarkers in the mother-infa...
Potassium bromate as a probable human Carcinogen: multi-organ toxicity and chemopreventive potential of dietary antioxidants-a comprehensive review [0.03%]
钾溴酸作为一种潜在的人类致癌物：饮食抗氧化剂的多器官毒性及化学预防潜力——全面综述
Saima Nazir,Mir Kaisar Ahmad
Saima Nazir
Potassium bromate (KBrO₃), classified as a probable human carcinogen, has long been used as a flour-improving and oxidizing agent in baking and food processing industries. It is also generated as a by-product during ozonation of drinking w...
Pavel Rossner Jr,Bozena Novotna,Daniela Pelclova et al.
Pavel Rossner Jr et al.
Human exposure to nanoparticles (NPs) poses potential health risks that are modulated, for example, by the physico-chemical characteristics of NPs, the exposure route and the dose of NPs. Among 21 workers involved for many years in welding ...
Ultra-Processed Foods and Diet Quality in Long COVID: Associations with Symptom Burden, DNA Damage, and Inflammation [0.03%]
长期新冠患者的超加工食物摄入与饮食质量、症状负担及DNA损伤和炎症的关系研究
Raquel D S Freitas,Ana Letícia H Garcia,Bruna Alves Alonso Martins et al.
Raquel D S Freitas et al.
Diet quality can be a potential modifier of post-acute COVID-19 syndrome (PACS), yet the relationship between dietary patterns, symptom burden, and biological markers remains poorly understood. We hypothesized that a low-quality diet would ...
In Vitro Cytogenotoxicity of Novel Tetrazole-Based Schiff Bases and Their Platinum (II) Complexes: A Detailed Analysis Using Chromosomal Aberration, Micronucleus, and Comet Assays [0.03%]
新型四氮唑舒夫碱及其铂(II)复合物的体外细胞遗传毒性：采用染色体 aberration、微核和彗星测定法的详细分析
Fatma Okuş,Deniz Yüzbaşıoğlu,Gonca Çakmak et al.
Fatma Okuş et al.
Previously, Tetrazole-based Schiff base ligands (TBSL) and their Pt(II) complexes were synthesized and evaluated for cytotoxic activity. The results revealed that low cytotoxicity for the ligands and moderate effects for the Pt(II) complexe...
Differential Roles of BRCA1 and BRCA2 in the DNA Damage Response Revealed by isogenic V79 Mutant Cell lines [0.03%]
同基因V79突变细胞系揭示BRCA1和BRCA2在DNA损伤反应中的不同作用
Piyawan Chailapakul,Junko Maeda,Tomisato Miura et al.
Piyawan Chailapakul et al.
This study aimed to establish a novel BRCA1 mutant cell line from Chinese hamster V79 cells and clarify the role of BRCA1 in the DNA damage response (DDR) by comparison with a BRCA2 mutant line, V-C8. Using CRISPR/Cas9 editing, we generated...