Unveiling the Genotoxic Safety and Antioxidant-Mediated DNA Protective Mechanisms of Triammonium Citrate: An Integrated In Vitro and In Silico Approach [0.03%]
三水合柠檬酸铵的基因毒安全性和抗氧化介导的DNA保护机制：一种整合的体外和分子对接模拟研究方法
Emin Öztürk,Hasan Basri İla
Emin Öztürk
Triammonium citrate (TAC) is a citrate salt widely utilized in diverse industrial and dietary applications, leading to widespread human exposure. While related citrate salts have established safety profiles, the specific genotoxic potential...
Nutritional maternal factors affect the frequency of DNA damage in newborns [0.03%]
营养性母体因素影响新生儿DNA损伤频率
Anny Cristine Araújo,Fabrícia de Medeiros Morais,Daline Fernandes de Souza Araújo et al.
Anny Cristine Araújo et al.
Maternal nutrition can influence genetic health during pregnancy, increasing the risk of DNA damage in both the mother and fetus. This study investigated the effect of maternal nutritional factors on DNA damage biomarkers in the mother-infa...
Potassium bromate as a probable human Carcinogen: multi-organ toxicity and chemopreventive potential of dietary antioxidants-a comprehensive review [0.03%]
钾溴酸作为一种潜在的人类致癌物：饮食抗氧化剂的多器官毒性及化学预防潜力——全面综述
Saima Nazir,Mir Kaisar Ahmad
Saima Nazir
Potassium bromate (KBrO₃), classified as a probable human carcinogen, has long been used as a flour-improving and oxidizing agent in baking and food processing industries. It is also generated as a by-product during ozonation of drinking w...
Pavel Rossner Jr,Bozena Novotna,Daniela Pelclova et al.
Pavel Rossner Jr et al.
Human exposure to nanoparticles (NPs) poses potential health risks that are modulated, for example, by the physico-chemical characteristics of NPs, the exposure route and the dose of NPs. Among 21 workers involved for many years in welding ...
Ultra-Processed Foods and Diet Quality in Long COVID: Associations with Symptom Burden, DNA Damage, and Inflammation [0.03%]
长期新冠患者的超加工食物摄入与饮食质量、症状负担及DNA损伤和炎症的关系研究
Raquel D S Freitas,Ana Letícia H Garcia,Bruna Alves Alonso Martins et al.
Raquel D S Freitas et al.
Diet quality can be a potential modifier of post-acute COVID-19 syndrome (PACS), yet the relationship between dietary patterns, symptom burden, and biological markers remains poorly understood. We hypothesized that a low-quality diet would ...
In Vitro Cytogenotoxicity of Novel Tetrazole-Based Schiff Bases and Their Platinum (II) Complexes: A Detailed Analysis Using Chromosomal Aberration, Micronucleus, and Comet Assays [0.03%]
新型四氮唑舒夫碱及其铂(II)复合物的体外细胞遗传毒性：采用染色体 aberration、微核和彗星测定法的详细分析
Fatma Okuş,Deniz Yüzbaşıoğlu,Gonca Çakmak et al.
Fatma Okuş et al.
Previously, Tetrazole-based Schiff base ligands (TBSL) and their Pt(II) complexes were synthesized and evaluated for cytotoxic activity. The results revealed that low cytotoxicity for the ligands and moderate effects for the Pt(II) complexe...
Differential Roles of BRCA1 and BRCA2 in the DNA Damage Response Revealed by isogenic V79 Mutant Cell lines [0.03%]
同基因V79突变细胞系揭示BRCA1和BRCA2在DNA损伤反应中的不同作用
Piyawan Chailapakul,Junko Maeda,Tomisato Miura et al.
Piyawan Chailapakul et al.
This study aimed to establish a novel BRCA1 mutant cell line from Chinese hamster V79 cells and clarify the role of BRCA1 in the DNA damage response (DDR) by comparison with a BRCA2 mutant line, V-C8. Using CRISPR/Cas9 editing, we generated...
Phytochemical compositions and chemoprotective effect of Lenzites betulinus mushroom in mononuclear cells of patients with acute coronary syndrome and heart failure in vitro [0.03%]
白杨树木霉菌的植物化学成分及其体外对急性冠状动脉综合征和心力衰竭单核细胞的防癌作用
Jovana Tubić Vukajlović,Ivan Simić,Tomislav Tosti et al.
Jovana Tubić Vukajlović et al.
Cardiovascular diseases (CVD) are the leading cause of death globally, posing a major public health challenge due to their increasing prevalence and complex etiology. Natural products from medicinal mushrooms have gained attention for their...
Multi-herbal ergogenic supplement induces in vitro mutagenicity and cytogenetic damages in HepG2 and HEK293 cells [0.03%]
一种多草本类的肌肉促进补充剂能诱导HepG2和HEK293细胞产生体内致突变以及染色体损伤
Eduardo Kennedy Carrão Dantas,João Pedro Franco Tabanela Thomé,Moisés de Oliveira Pontes Filho et al.
Eduardo Kennedy Carrão Dantas et al.
Popular ergogenic supplements for weight loss raise safety concerns due to potential cardiovascular, liver, and kidney toxicity. Their genotoxicity remains insufficiently studied, highlighting the need for more research on their long-term e...
Sachi Prasad Ray-Chaudhuri: Drosophila Genetics and Mutagenesis in Indian Science [0.03%]
萨奇·普拉asad·雷-查德胡里：印度科学中的果蝇遗传学和诱变
Rajiva Raman,Awadhesh N Jha
Rajiva Raman
This article summarizes the scientific contributions of Professor Sachi Prasad Ray-Chaudhuri and his unwavering commitment to advancing research and teaching in mutagenesis and genetics in post-independence India, following his postgraduate...