Bitter taste receptors [0.03%]
苦味受体
Maik Behrens,Silvia Schaefer
Maik Behrens
Hundreds of bitter substances, synthetic or natural, toxic or health beneficial, chemically complex organic molecules or simple inorganic metal salts, surround us and other vertebrates. Their detection is mediated by bitter taste receptors ...
Nasal xenobiotic metabolizing enzymes: at the crossroads of toxicity, detoxification, and olfaction [0.03%]
鼻内异生物代谢酶：毒物、解毒和嗅觉的交汇点
Fabrice Neiers,Mathieu Schwartz,Nicole Kornbausch et al.
Fabrice Neiers et al.
Enzymes exemplify the adaptability of biological systems through their multifunctional roles across tissues. Thus, xenobiotic metabolizing enzymes, traditionally recognized for their contributions to detoxification, biosynthesis, and signal...
Diversity in chemosensory receptor genes in dogs and wolves: degeneration of the olfactory receptor gene repertoire in the brachycephalic Pug [0.03%]
犬和狼的化学感觉受体基因多样性：短头型狆犬嗅觉受体基因的退化
Hyuga Inoue,Matthew Gibbs,Scott J McGrane et al.
Hyuga Inoue et al.
Dogs, domesticated from gray wolves over 15,000 yr ago, exhibit extensive variation among breeds, including differences in olfactory ability. To investigate the genetic basis of these differences, we analyzed single-nucleotide variants (SNV...
Courtney E Wilson,Sue C Kinnamon
Courtney E Wilson
This review outlines the specific ion channels, taste cell types, downstream signaling, and neural transmission mechanisms involved in the perception of sour and salty tastes. Both of these taste qualities arise from ionic stimuli and so ca...
Christopher Creighton,Anupama Dahanukar
Christopher Creighton
The ability to discern nutritious food from harmful substances is critical for animal survival, with the gustatory system playing a pivotal role. In insects, including the genetic model Drosophila melanogaster, taste perception involves mor...
Complement activation correlates with impaired olfactory function in patients with chronic rhinosinusitis with nasal polyps [0.03%]
补体激活与鼻息肉型慢性鼻窦炎患者嗅觉功能障碍相关性研究
Sufiya Ali,Alexander O Johnson,Maria Villanueva et al.
Sufiya Ali et al.
The mechanisms that contribute to CRSwNP-related olfactory loss are poorly characterized. We have previously shown in middle meatus mucus that levels of C3, a component of the complement system, are elevated and correlate with worse disease...
Descending projections from the central nucleus of the amygdala synapse with different neuron types in the nucleus of the solitary tract [0.03%]
中央杏仁核投射到孤束核的神经元连接不同类型的神经元
Jane Bartonjo,Abigail Muccilli,Robert Lundy
Jane Bartonjo
Several forebrain areas project to the rostral gustatory portion of the nucleus of the solitary tract (rNST), where they modulate processing of oral gustatory signals. Among them, the central nucleus of the amygdala (CeA) provides descendin...
Adult Drosophila aversion to caffeine requires a unique TrpA1 isoform and the PLC signaling cascade [0.03%]
成年果蝇对咖啡因的厌恶反应需要一种独特的TrpA1亚型和磷脂酶C信号传导通路
Romane Milleville,Jade Gillas,Amanda Thuy La et al.
Romane Milleville et al.
Taste in Drosophila melanogaster is crucial to survival, influencing feeding, mating, and egg-laying behaviors. Taste organs are located on various parts of the body, including the legs, proboscis, wings, and ovipositor. Taste neurons detec...
Effect of taste recall training using five sweet substances on sweet taste sensitivities [0.03%]
五种甜味物质回味训练对甜味敏感性的影响
Uijin Park,Midori Miyagi,Satoru Ebihara
Uijin Park
The mechanisms involved in the discrimination of basic tastes have been previously studied. However, the mechanisms that differentiate between various substances within the same taste quality remain largely unexplored. This study aimed to d...
It takes two: intranasal trigeminal chemosensation and its role in odor processing [0.03%]
鼻内三叉神经化学感觉及其在气味处理中的作用
Chloé Migneault-Bouchard,Claire Martin,Johannes Frasnelli et al.
Chloé Migneault-Bouchard et al.
Odor perception is a complex, multimodal experience mainly shaped by the interaction between the olfactory and trigeminal systems. Descriptors such as warm, fresh, or spicy reflect the contribution of chemosensory input from the trigeminal ...