Plasma metabolomics and incident major adverse cardiovascular events in patients with rheumatoid arthritis [0.03%]
代谢组学与类风湿关节炎患者主要不良心血管事件的关系研究
Christos P Kotanidis,Priyam Choksi,Pradeep Natarajan et al.
Christos P Kotanidis et al.
Objectives: Patients with rheumatoid arthritis (RA) have excess cardiovascular risk beyond traditional factors. We evaluated associations between plasma metabolites and incident major adverse cardiovascular events (MACE) ...
Association of Th2-like inflammation with a Tfh/Tph-germinal center immune programs in submandibular gland lesions of IgG4-related disease [0.03%]
IgG4相关性疾病下颌下腺病灶中Th2样炎症与Tfh/Tph生发中心免疫程序的相关性研究
Motohisa Yamamoto,Ryuta Kamekura,Masaaki Uehara et al.
Motohisa Yamamoto et al.
Objectives: IgG4-related disease (IgG4-RD) has long been associated with Th2-predominant immune responses and allergic features. However, the immunological context underlying lesional Th2-like inflammation remains incompl...
A simple questionnaire to prevent blindness-a cross-sectional study screening for Stickler syndrome in children [0.03%]
儿童Uveitis-Stickler综合征的筛查及预防失明的简易问卷调查——横断面研究
Robert Smyth,Peter Bale,Thomas R W Nixon et al.
Robert Smyth et al.
Objectives: Stickler syndrome is a skeletal dysplasia that is widely under-recognised yet the most common cause of inherited retinal detachment in children. The most prevalent subtype is Stickler syndrome type 1 (STL1), w...
Genome-wide methylation profiling identifies signatures of pain, fatigue, and health scores in women with systemic lupus erythematosus [0.03%]
全基因组甲基化谱分析确定了系统性红斑狼疮女性患者疼痛、疲劳和健康评分的特征标志
Alessandro Camponeschi,Amin Ravaei,Tahzeeb Fatima et al.
Alessandro Camponeschi et al.
Objectives: People with Systemic Lupus Erythematosus (SLE) experience high levels of pain and fatigue with poor overall health, which persist in those with low disease activity. By performing epigenome-wide DNA methylatio...
High levels of Vascular Cell Adhesion Molecule 1 associate with a "vasculopathic" phenotype in systemic sclerosis with higher mortality [0.03%]
血管细胞粘附分子1高水平与系统性硬化症的“血管病变”表型及更高的死亡率相关
Matthew J S Parker,Mandana Nikpour,Dylan Hansen et al.
Matthew J S Parker et al.
Objectives: To determine disease-specific associations of serum vascular cell adhesion molecule-1 (VCAM-1) and associated mortality in systemic sclerosis (SSc). ...
A genome-wide cross-trait analysis characterises the shared genetic architecture between rheumatoid arthritis and psychiatric disorders [0.03%]
全基因组交叉性状分析揭示了类风湿关节炎和精神障碍之间的共享遗传结构
Xin Ke,Shi Yao,Xi Zheng et al.
Xin Ke et al.
Objectives: Patients with rheumatoid arthritis (RA) have a 2- to 3-fold elevated risk of psychiatric disorders, suggesting an underlying genetic link between these phenotypes. However, the shared genetic architectures and...
Prolonged serologically active clinically quiescent systemic lupus erythematosus: a longitudinal study on the role of IgG anti-dsDNA and C3 [0.03%]
长期血清学活跃且临床静止的系统性红斑狼疮纵向研究：IgG抗dsDNA和C3的作用
Silvia Piunno,Augusta Ortolan,Luigi Zolio et al.
Silvia Piunno et al.
Objectives: To assess whether fluctuations in Immunoglobulin G anti-double stranded DNA (IgG anti-dsDNA) antibodies and C3 levels predict flares and sustained activity in patients with prolonged serologically active clini...
Radiographic progression in psoriatic arthritis: head-to-head comparison of the Ratingen score and the Sharp-van der Heijde method [0.03%]
银屑病关节炎的放射学进展：Ratingen评分与Sharp-van der Heijde法的比较
Myroslava Kulyk,Silvia Scriffignano,Serge Steinfeld et al.
Myroslava Kulyk et al.
Objectives: To compare the psychometric properties (inter-rater reliability, agreement, responsiveness, and measurement error) of the Psoriatic Arthritis Ratingen Score (PARS) and modified Sharp-van der Heijde (SVDH) meth...
Tamara Vojinovic,Johan Askling,Aleksandra Antovic
Tamara Vojinovic
Rheumatoid arthritis (RA) is associated with a markedly increased risk of venous thromboembolism (VTE), reflecting a complex interplay between chronic inflammation, immune dysregulation, and hemostatic imbalance. Large population-based stud...