Jiantong Dong,Michael P O&#x;Hagan,Itamar Willner
Jiantong Dong
G-Quadruplexes attract growing interest as functional constituents in biology, chemistry, nanotechnology, and material science. In particular, the reversible dynamic reconfiguration of G-quadruplexes provides versatile means to switch DNA n...
Tomoya Ishizuka,Nitika Grover,Christopher J Kingsbury et al.
Tomoya Ishizuka et al.
Porphyrins are variously substituted tetrapyrrolic macrocycles, with wide-ranging biological and chemical applications derived from metal chelation in the core and the 18π aromatic surface. Under suitable conditions, the porphyrin framewor...
Medicinal inorganic chemistry - challenges, opportunities and guidelines to develop the next generation of radioactive, photoactivated and active site inhibiting metal-based medicines [0.03%]
医药无机化学：开发下一代放射性、光活化和作用位点抑制金属基药物的挑战、机遇和指导方针
Raphael Lengacher,Axia Marlin,Dariusz Śmiłowicz et al.
Raphael Lengacher et al.
Medicinal inorganic chemistry is a burgeoning subfield of medicinal chemistry that focuses on the development of metal-based diagnostic and therapeutic agents. This tutorial review aims to provide an introductory primer, present a timely ov...
Metal-organic framework (MOF)-, covalent-organic framework (COF)-, and porous-organic polymers (POP)-catalyzed selective C-H bond activation and functionalization reactions [0.03%]
金属有机骨架（MOF）、共价有机骨架（COF）和多孔有机聚合物（POP）催化C-H键活化及功能化反应
Saba Daliran,Ali Reza Oveisi,Yong Peng et al.
Saba Daliran et al.
Although C-H functionalization is one of the simplest reactions, it requires the use of highly active and selective catalysts. Recently, C-H-active transformations using porous materials such as crystalline metal-organic frameworks (MOFs) a...
How can we use the endocytosis pathways to design nanoparticle drug-delivery vehicles to target cancer cells over healthy cells? [0.03%]
如何利用内吞途径设计 nanoparticles 以特异性杀伤癌细胞
Vu Thanh Cong,Jacinta L Houng,Maria Kavallaris et al.
Vu Thanh Cong et al.
Targeted drug delivery in cancer typically focuses on maximising the endocytosis of drugs into the diseased cells. However, there has been less focus on exploiting the differences in the endocytosis pathways of cancer cells versus non-cance...
Ming-Ming Wang,Tin V T Nguyen,Jerome Waser
Ming-Ming Wang
Aminocyclopropanes are versatile building blocks for accessing high value-added nitrogen-containing products. To control ring-opening promoted by ring strain, the Lewis acid activation of donor-acceptor substituted systems is now well estab...
Bowen Yang,Dmitry Bogachuk,Jiajia Suo et al.
Bowen Yang et al.
Halide perovskite solar cells (PSCs) have achieved power conversion efficiencies (PCEs) approaching 26%, however, the stability issue hinders their commercialization. Due to the soft ionic nature of perovskite materials, the strain effect o...
Linyang Li,Yabei Xia,Mengqi Zeng et al.
Linyang Li et al.
Ultrathin two-dimensional (2D) materials exhibit broad application prospects in many fields due to the enhanced specific surface area to volume ratio and quantum confinement effect. Because of the atomic thickness and various orientations, ...
Abtin Ebadi Amooghin,Hamidreza Sanaeepur,Rafael Luque et al.
Abtin Ebadi Amooghin et al.
Fluorinated metal-organic frameworks (F-MOFs) as fast-growing porous materials have revolutionized the field of gas separation due to their tunable pore apertures, appealing chemical features, and excellent stability. A deep understanding o...
Putting precision and elegance in enzyme immobilisation with bio-orthogonal chemistry [0.03%]
利用生物正交化学使酶固定化的精密度与优雅性
Xiaolin Pei,Zhiyuan Luo,Li Qiao et al.
Xiaolin Pei et al.
The covalent immobilisation of enzymes generally involves the use of highly reactive crosslinkers, such as glutaraldehyde, to couple enzyme molecules to each other or to carriers through, for example, the free amino groups of lysine residue...