Glyco-Forum [0.03%]
糖工程论坛
Karen Colley
Karen Colley
One-pot synthesis of lacto-N-tetraose using a glycosynthase engineered from GH136 lacto-N-biosidase LnbX [0.03%]
一种源自GH136型乳糖神经酰胺酶LnbX的甘露糖苷合成酶在单锅法合成四乳糖神经节苷脂中的应用研究
Noriki Fujio,Ryota Umekage,Ami Ishikawa et al.
Noriki Fujio et al.
Lacto-N-tetraose (LNT: Galβ1-3GlcNAcβ1-3Galβ1-4Glc) is the most abundant core structure of human milk oligosaccharides (HMOs) and plays important roles in establishing healthy microbiota in the infant gut. Several enzymatic strategies ha...
Glyco You Should Know [0.03%]
你应该了解的糖类知识
Aminul Islam
Aminul Islam
Introduction to a Special Issue of Glycobiology-Glycobiology Reviews Cancer [0.03%]
糖生物学专刊介绍-糖生物学癌症评论导言
Richard D Cummings,Susan L Bellis
Richard D Cummings
Cell Surface Glycans: From Recognition Technologies and Functional Editing to Medical Applications [0.03%]
细胞表面糖类：从识别技术、功能编辑到医学应用
Tingting Zhang,Yongbin Xu,Yupeng Liu et al.
Tingting Zhang et al.
Cell-surface glycans play essential roles in cell communication, immune recognition, and disease progression. Their medical applications are supported by two important technological pillars: glycan recognition and glycan editing. This Revie...
Aberrant O-glycosylation genes and miR-21-5p targets define a molecular signature of tumor aggressiveness in triple-negative breast cancer [0.03%]
异常的O-糖基化基因和miR-21-5p靶标定义了三阴性乳腺癌肿瘤侵袭性的分子特征
Alexis Germán Murillo Carrasco,Mercedes Landeira,Tatiane Katsue Furuya et al.
Alexis Germán Murillo Carrasco et al.
Aberrant O-glycosylation and miRNA dysregulation are established features of tumor aggressiveness, particularly in triple-negative breast cancer (TNBC). Using a Cosmc-silenced 4 T1 murine model (Tn+), characterized by truncated O-glycans an...
José Pires,Eric Rochat,Ieva Bagdonaite et al.
José Pires et al.
Aberrant O-GalNAc glycans such as Tn, STn, and T are among the most consistent tumor-associated carbohydrate antigens, broadly expressed on carcinomas but largely absent from healthy epithelia. In parallel, O-glycans can also be modified to...
Glyco you should know [0.03%]
你应该了解的糖化学
Gracie Carlson
Gracie Carlson
Biosynthesis of human milk oligosaccharides (HMOs) in glycoengineered human cells [0.03%]
用人源化工程细胞合成人类乳汁低聚糖(HMOs)
Stijn Kruf,Roy J B M Delahaije,Khadra A Mohamed et al.
Stijn Kruf et al.
Human milk oligosaccharides (HMOs) are unconjugated and structurally diverse glycans synthesized in the lactating mammary gland through the stepwise action of glycosyltransferases that extend a free lactose core. Several HMOs are capped wit...
Glyco You Should Know [0.03%]
你应该了解的糖类生物学
Tetsuya Hirata
Tetsuya Hirata