One-pot synthesis of lacto-N-tetraose using a glycosynthase engineered from GH136 lacto-N-biosidase LnbX
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Lacto-N-tetraose (LNT: Galβ1-3GlcNAcβ1-3Galβ1-4Glc) is the most abundant core structure of human milk oligosaccharides (HMOs) and plays important roles in establishing healthy microbiota in the infant gut. Several enzymatic strategies have been developed fo... ...
