Human antral follicles <6 mm: a comparison between in vivo maturation and in vitro maturation in non-hCG primed cycles using cumulus cell gene expression [0.03%]
人窦状卵泡
L Guzman,T Adriaenssens,C Ortega-Hrepich et al.
L Guzman et al.
Within the context of an oocyte in vitro maturation (IVM) program for reproductive treatment, oocyte cumulus complexes (COCs) derived from follicles
Comparative Study
Molecular human reproduction. 2013 Jan;19(1):7-16. DOI:10.1093/molehr/gas038 2013
Gene-environment interaction in preterm delivery with special reference to organochlorine pesticides [0.03%]
有机氯杀虫剂与基因-环境交互作用在早产中的影响研究
M D Mustafa,B D Banerjee,Rafat S Ahmed et al.
M D Mustafa et al.
We investigated the association between glutathione S-transferases mu1 (GSTM1), theta 1 (GSTT1), Cytochrome P450IA1-T6235C (rs4646903, CYP1A1m1) and CYP1A1-1462V (rs1048943, CYP1A1m2) gene polymorphisms, and organochlorine pesticides (OCPs)...
False-positive antibody signals for the pluripotency factor OCT4A (POU5F1) in testis-derived cells may lead to erroneous data and misinterpretations [0.03%]
测试阳性OCT4A(POU5F1)多能性标记误导睾丸源细胞系数据及错误解读
R Warthemann,K Eildermann,K Debowski et al.
R Warthemann et al.
Octamer-binding protein 4 (OCT4) is a key player in pluripotent embryonic stem (ES) cells and is essential for the generation of induced pluripotent stem cells. Recently, several reports indicated the spontaneous recovery of pluripotency in...
Specific genes are selectively expressed between cumulus and granulosa cells from individual human pre-ovulatory follicles [0.03%]
特定基因在单个卵泡的放射冠细胞和颗粒细胞中选择性表达
M L Grøndahl,C Yding Andersen,J Bogstad et al.
M L Grøndahl et al.
During folliculogenesis, the granulosa cells differentiate into two cell types: cumulus cells (CCs) and mural granulosa cells (MGCs). The objective of the study was to generate and compare the transcriptomes of MGCs and CCs from the pre-ovu...
The molecular connections between the cannabinoid system and endometriosis [0.03%]
大麻素系统与子宫内膜异位症之间的分子联系
A M Sanchez,P Vigano,A Mugione et al.
A M Sanchez et al.
The endocannabinoid system consists of an array of endogenously produced bioactive lipids that activate cannabinoid 1 (CB1) and 2 (CB2) receptors. Alterations of this system have been described in almost every category of disease. These cha...
Mosaic moles and non-familial biparental moles are not caused by mutations in NLRP7, NLRP2 or C6orf221 [0.03%]
镶嵌型痣和非家族性双亲缘性痣的发病与NLRP7,NLRP2或C6orf221基因突变无关
L Andreasen,L Bolund,I Niemann et al.
L Andreasen et al.
Hydatidiform moles (HMs) most often occur sporadically and are either diploid androgenetic or triploid. The very rare familial recurrent HMs (FRHMs) have been related to NLRP7 and C6orf221 mutations in the mother. FRHMs are most often diplo...
Molecular studies of the congenital malformation induced by Largehead Atractylodes Rhizome, the most commonly used Chinese medicine for threatened miscarriage [0.03%]
广藤黄淫羊藿诱导小鼠先天性畸形的分子机理研究
L Y Tang,L Li,A Borchert et al.
L Y Tang et al.
Largehead Atractylodes Rhizome (LAR) is the most commonly used Chinese herbal medicine for threatened miscarriage. Potential reproductive toxicity of LAR was identified in early pregnancy in animals. Skeletal anomalies including loss of uln...
Analysis of meiosis regulators in human gonads: a sexually dimorphic spatio-temporal expression pattern suggests involvement of DMRT1 in meiotic entry [0.03%]
人类生殖腺中的减数分裂调节因子分析:性别二态性时空表达模式表明DMRT1参与减数分裂的进入
Anne Jørgensen,John E Nielsen,Martin Blomberg Jensen et al.
Anne Jørgensen et al.
The mitosis-meiosis switch is a key event in the differentiation of germ cells. In humans, meiosis is initiated in fetal ovaries, whereas in testes meiotic entry is inhibited until puberty. The purpose of this study was to examine the expre...
HORMAD2/CT46.2, a novel cancer/testis gene, is ectopically expressed in lung cancer tissues [0.03%]
新型癌症/睾丸基因HORMAD2/CT46.2在肺癌组织中异位表达
Mingxi Liu,Jiaping Chen,Lingmin Hu et al.
Mingxi Liu et al.
Recently, it has been shown that ectopic expression of several germ line genes, such as piwi, vasa, nos and aub, drives the growth of malignant brain tumors in Drosophila. A genome-wide association study (GWAS) of ~18 000 subjects indicated...