Heparin inhibits TNF-α signaling in human endometrial stromal cells by interaction with NF-κB [0.03%]
肝素通过与NF-κB相互作用抑制TNF-α在人类子宫内膜基质细胞中的信号转导
Julia Spratte,Henriette Meyer zu Schwabedissen,Nicole Endlich et al.
Julia Spratte et al.
Heparins have been shown to be beneficial for the prevention of habitual miscarriages and repeated implantation failure, independently of their function as anticoagulants. The pro-inflammatory cytokine tumor necrosis factor (TNF)-α plays a...
Zhan Ma,Ruilai Liu,Xiaojin Wang et al.
Zhan Ma et al.
The germ-cell lineage in mammals is believed to separate from somatic lineages around the time of gastrulation. We present data showing that germline cells can originate from a human hepatic cell line (HL7702) in vitro. In specific culture ...
The effects of whole ovarian perfusion and cryopreservation on endothelial cell-related gene expression in the ovarian medulla and pedicle [0.03%]
完整卵巢灌注和冷冻保存对卵巢髓质和卵巢悬韧带内皮细胞相关基因表达的影响
V J Onions,R Webb,C Pincott-Allen et al.
V J Onions et al.
Fertility preservation by whole ovarian cryopreservation requires successful cryopreservation of both the ovary and its vascular supply. Previous work has indicated detrimental effects of both perfusion and cryopreservation on the ovarian v...
Steroidogenic enzyme expression in the human fetal liver and potential role in the endocrinology of pregnancy [0.03%]
人胎儿肝脏中的类固醇生成酶的表达及其在妊娠内分泌学中的潜在作用
P J O&#x;Shaughnessy,A Monteiro,S Bhattacharya et al.
P J O&#x;Shaughnessy et al.
The human feto-maternal unit produces large amounts of steroid hormones, particularly estrogens, during the second and third trimesters. The fetal adrenal gland and the placenta are considered the principal tissues driving steroid productio...
Leptin receptor is induced in endometriosis and leptin stimulates the growth of endometriotic epithelial cells through the JAK2/STAT3 and ERK pathways [0.03%]
瘦素受体在子宫内膜异位症中被诱导及瘦素通过JAK2 / STAT3和ERK途径刺激子宫内膜异位上皮细胞的生长
Hoon Kyu Oh,Youn Seok Choi,Yeong-In Yang et al.
Hoon Kyu Oh et al.
Leptin acts as a potential growth stimulator in several normal and neoplastic cells. Recent studies have shown the presence of increased levels of leptin in the peritoneal fluid of patients with endometriosis, implicating leptin in the path...
Association between the SERPINE1 (PAI-1) 4G/5G insertion/deletion promoter polymorphism (rs1799889) and pre-eclampsia: a systematic review and meta-analysis [0.03%]
血管紧张素转换酶插入/删除基因型与慢性高血压孕妇子痫前期发病风险的关联：一项系统综述和荟萃分析
Linlu Zhao,Michael B Bracken,Andrew T Dewan et al.
Linlu Zhao et al.
The SERPINE1 -675 4G/5G promoter region insertion/deletion polymorphism (rs1799889) has been implicated in the pathogenesis of pre-eclampsia (PE), but the genetic association has been inconsistently replicated. To derive a more precise esti...
Promoter hypomethylation of TIMP3 is associated with pre-eclampsia in a Chinese population [0.03%]
TIMP3启动子低甲基化与中国人妊娠期高血压疾病的关系研究
Yuqian Xiang,Xiaojing Zhang,Qiaoli Li et al.
Yuqian Xiang et al.
A study by Yuen RK, Penaherrera MS, von Dadelszen P, McFadden DE, Robinson WP. DNA methylation profiling of human placentas reveals promoter hypomethylation of multiple genes in early-onset preeclampsia. Eur J Hum Genet 2010;18:1006-1012 ba...
Expression and localization of inhibitor of differentiation (ID) proteins during tissue and vascular remodelling in the human corpus luteum [0.03%]
人黄体组织和血管重塑过程中抑制蛋白(ID蛋白)的表达及定位分布研究
Junko Nio-Kobayashi,Rachna Narayanan,Sevasti Giakoumelou et al.
Junko Nio-Kobayashi et al.
Members of the transforming growth factor-β (TGF-β) superfamily are likely to have major roles in the regulation of tissue and vascular remodelling in the corpus luteum (CL). There are four inhibitor-of-differentiation (ID1-4) genes that ...
Oncogenic Wnt/β-catenin signalling pathways in the cancer-resistant epididymis have implications for cancer research [0.03%]
致癌的Wnt/β-连环蛋白信号通路在癌症抵抗性附睾中的作用对癌症研究具有重要意义
K Wang,N Li,C H Yeung et al.
K Wang et al.
Aberrant activation of the Wnt/β-catenin pathway occurs in cancers. This review presents several important cancer-related aspects of Wnt/β-catenin signalling relevant to the epididymis, provides evidence of such epididymal gene expression...
Maternal smoking as a model for environmental epigenetic changes affecting birthweight and fetal programming [0.03%]
母亲吸烟引起表观遗传改变影响新生儿体重及胎儿程序化的模型研究
Melissa A Suter,Amber M Anders,Kjersti M Aagaard
Melissa A Suter
Although the association between maternal smoking and low birthweight infants has been well established, the mechanisms behind reduced fetal growth are still being elucidated. While many infants are exposed to tobacco smoke in utero, not al...