In vivo effect of vaginal seminal plasma application on the human endometrial transcriptome: a randomized controlled trial [0.03%]
人乳头状瘤病毒阴性的中国女性接种HPV-16/18AS04型疫苗免疫原性：一项随机对照研究
Laura Catalini,Mark Burton,Dorte L Egeberg et al.
Laura Catalini et al.
Studies in humans and animals suggest that seminal plasma, the acellular seminal fluid component, stimulates the endometrium to promote immune tolerance and facilitate implantation. We designed a randomized, double-blinded, placebo-controll...
Randomized Controlled Trial
Molecular human reproduction. 2024 Mar 28;30(5):gaae017. DOI:10.1093/molehr/gaae017 2024
Paxillin regulates androgen receptor expression associated with granulosa cell focal adhesions [0.03%]
波形蛋白调节与颗粒细胞焦粘附相关的雄激素受体表达
Adelaide E Weidner,Anna Roy,Kenji Vann et al.
Adelaide E Weidner et al.
Paxillin is a ubiquitously expressed adaptor protein integral to focal adhesions, cell motility, and apoptosis. Paxillin has also recently been implicated as a mediator of nongenomic androgen receptor (AR) signaling in prostate cancer and o...
Methyl-CpG-binding protein 2 regulates CYP27A1-induced myometrial contraction during preterm labor [0.03%]
甲基胞嘧啶 CG 基序结合蛋白 2 在早产期间通过 CYP27A1 调节子宫平滑肌收缩
Ting Peng,Jiayan Cui,Ziyun Ni et al.
Ting Peng et al.
Persistent and intense uterine contraction is a risk factor for preterm labor. We previously found that methyl-CpG-binding protein 2 (MeCP2), as a target of infection-related microRNA miR-212-3p, may play an inhibitory role in regulating my...
Cellular senescence of granulosa cells in the pathogenesis of polycystic ovary syndrome [0.03%]
颗粒细胞衰老在多囊卵巢综合征发病机制中的作用
Tsurugi Tanaka,Yoko Urata,Miyuki Harada et al.
Tsurugi Tanaka et al.
Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders in women of reproductive age, but its pathology has not been fully characterized and the optimal treatment strategy remains unclear. Cellular senescence is a per...
A new initiative for 2024: increasing peer review transparency at MHR [0.03%]
2024年新举措：在MHR增加同行评审透明度
Michele Boiani,Francesca E Duncan
Michele Boiani
Correction to: Aggregated chromosomes/chromatin transfer: a novel approach for mitochondrial replacement with minimal mitochondrial carryover: the implications of mouse experiments for human aggregated chromosome transfer [0.03%]
correction to: 汇集的染色体/染色质转移：一种新的最小化线粒体携带量的人类线粒体替换方法：小鼠实验对人类汇集染色体传输的意义研究
Published Erratum
Molecular human reproduction. 2024 Mar 28;30(4):gaae013. DOI:10.1093/molehr/gaae013 2024
Correction to: Reduced oxygen concentrations regulate the phenotype and function of human granulosa cells in vitro and cause a diminished steroidogenic but increased inflammatory cellular reaction [0.03%]
更正：减少氧浓度调节人类颗粒细胞的表型和功能并导致类固醇反应降低而炎症反应增加的体外研究
Published Erratum
Molecular human reproduction. 2024 Feb 29;30(3):gaae011. DOI:10.1093/molehr/gaae011 2024
Influx of innovation: promoting the scientific advances of early career investigators in Molecular Human Reproduction [0.03%]
创新的涌入：促进《分子人类生殖》早期职业研究者们的科学进展
Francesca E Duncan,Michele Boiani
Francesca E Duncan
Michele Boiani;MHR-ISSCR guidelines working group
Michele Boiani;MHR-ISSCR guidelines working group
Extracellular vesicle-encapsulated miR-25-3p promotes epithelial-mesenchymal transition and migration of endometrial epithelial cells by inducing macrophage polarization [0.03%]
胞外囊泡包裹的miR-25-3p通过诱导巨噬细胞极化促进子宫上皮细胞的上皮间质转化和迁移
Yue Hu,Ming Yuan,Lei Cheng et al.
Yue Hu et al.
The pathogenesis of adenomyosis is closely related to the epithelial-mesenchymal transition and macrophages. MicroRNAs have been extensively investigated in relation to the epithelial-mesenchymal transition in a range of malignancies. Howev...