Genetic risk factors for endometriosis near estrogen receptor 1 and coexpression of genes in this region in endometrium [0.03%]
雌激素受体附近影响子宫内膜异位的遗传风险因素及该区域基因在子宫内膜中的共同表达
S Marla,S Mortlock,S Houshdaran et al.
S Marla et al.
The etiology and pathogenesis of endometriosis are complex with both genetic and environmental factors contributing to disease risk. Genome-wide association studies (GWAS) have identified multiple signals in the estrogen receptor 1 (ESR1) r...
Genetic risk factors for endometriosis near estrogen receptor 1 and coexpression of genes in this region in endometrium [0.03%]
雌激素受体1附近的子宫内膜异位症遗传危险因素及该区域基因在子宫内膜中的共同表达
S Marla,S Mortlock,S Houshdaran et al.
S Marla et al.
The etiology and pathogenesis of endometriosis are complex with both genetic and environmental factors contributing to disease risk. Genome-wide association studies (GWAS) have identified multiple signals in the estrogen receptor 1 (ESR1) r...
Genetic risk factors for endometriosis near estrogen receptor 1 and coexpression of genes in this region in endometrium [0.03%]
雌激素受体1附近的子宫内膜异位症遗传危险因素及此区域基因在子宫内膜的共表达
S Marla,S Mortlock,S Houshdaran et al.
S Marla et al.
The etiology and pathogenesis of endometriosis are complex with both genetic and environmental factors contributing to disease risk. Genome-wide association studies (GWAS) have identified multiple signals in the estrogen receptor 1 (ESR1) r...
G N Subramanian,M Lavin,H A Homer
G N Subramanian
Premature loss of ovarian activity before 40 years of age is known as primary ovarian insufficiency (POI) and occurs in ∼1% of women. A more subtle decline in ovarian activity, known as premature ovarian ageing (POA), occurs in ∼10% of wo...
Humanin regulates oxidative stress in the ovaries of polycystic ovary syndrome patients via the Keap1/Nrf2 pathway [0.03%]
人胎盘溶素通过Keap1/Nrf2途径调节多囊卵巢综合征患者卵巢氧化应激水平
Yingying Wang,Nianyu Li,Zhengyan Zeng et al.
Yingying Wang et al.
Polycystic ovary syndrome (PCOS) is the most common endocrinological pathology among women of reproductive age, whereas the pathogenesis is still not fully understood. Systemic and ovarian oxidative stress (OS) imbalance is a pivotal featur...
Hamid Reza Nejabati,Vahideh Shahnazi,Yousef Faridvand et al.
Hamid Reza Nejabati et al.
Darwin, in the pangenesis theory, imagined particles, named as 'gemmules', which are released from all ('pan') cells of the body. By cell-cell communication and also circulation through the body, they finally reach the germ cells to partici...
Gisela Soledad Gualdoni,Patricia Verónica Jacobo,Cristian Marcelo Sobarzo et al.
Gisela Soledad Gualdoni et al.
Experimental autoimmune orchitis (EAO) is a useful model to study organ-specific autoimmunity and chronic testicular inflammation. This model reflects testicular pathological changes reported in immunological infertility in men. Progression...
Placental multipotent mesenchymal stromal cell-derived Slit2 may regulate macrophage motility during placental infection [0.03%]
胎盘多能间充质干细胞衍生的Slit2可能在胎盘感染期间调节巨噬细胞运动性
Chie-Pein Chen,Liang-Kai Wang,Chen-Yu Chen et al.
Chie-Pein Chen et al.
Slit proteins have been reported to act as axonal repellents in Drosophila; however, their role in the placental microenvironment has not been explored. In this study, we found that human placental multipotent mesenchymal stromal cells (hPM...
Teruhiko Kawamura,Hiroyuki Tomari,Ichiro Onoyama et al.
Teruhiko Kawamura et al.
Ageing of the uterine endometrium is a critical factor that affects reproductive success, but the mechanisms associated with uterine ageing are unclear. In this study, we conducted a qualitative examination of age-related changes in endomet...
Comparative Study
Molecular human reproduction. 2021 Feb 5;27(2):gaaa078. DOI:10.1093/molehr/gaaa078 2021
HMGA2-induced epithelial-mesenchymal transition is reversed by let-7d in intrauterine adhesions [0.03%]
HMGA2诱导的上皮间质转化通过let-7d在宫腔粘连中被逆转
Minmin Song,Chenrui Cao,Zhenhua Zhou et al.
Minmin Song et al.
Intrauterine adhesions (IUAs), the leading cause of uterine infertility, are characterized by endometrial fibrosis. The management of IUA is challenging because the pathogenesis of the disease largely unknown. In this study, we demonstrate ...