Testicular adenosine acts as a pro-inflammatory molecule: role of testicular peritubular cells [0.03%]
睾丸腺苷具有促炎作用：睾丸间质细胞的作用不容忽视
Annika Missel,Lena Walenta,Katja Eubler et al.
Annika Missel et al.
Extracellular ATP has been described to be involved in inflammatory cytokine production by human testicular peritubular cells (HTPCs). The ectonucleotidases ENTPD1 and NT5E degrade ATP and have been reported in rodent testicular peritubular...
Endometrial epithelial-mesenchymal transition (EMT) by menstruation-related inflammatory factors during hypoxia [0.03%]
月经相关炎症因子介导的子宫内膜上皮间质转化(EMT)反应及低氧影响机制研究
K Kusama,Y Fukushima,K Yoshida et al.
K Kusama et al.
Endometriosis is characterised by inflammation and fibrotic changes. Our previous study using a mouse model showed that proinflammatory factors present in peritoneal haemorrhage exacerbated inflammation in endometriosis-like grafts, at leas...
Two alternative methods for the retrieval of somatic cell populations from the mouse ovary [0.03%]
从小鼠卵巢中获取体细胞群体的两种替代方法
E R Frost,E A Ford,G Taylor et al.
E R Frost et al.
Many modern techniques employed to uncover the molecular fundamentals underlying biological processes require dissociated cells as their starting point/substrate. Investigations into ovarian endocrinology or folliculogenesis, therefore, nec...
The RNA content of human sperm reflects prior events in spermatogenesis and potential post-fertilization effects [0.03%]
人类精子中的RNA含量反映了精子发生过程中的先前事件及潜在的受精后效应
C Corral-Vazquez,J Blanco,R Aiese Cigliano et al.
C Corral-Vazquez et al.
Transcriptome analyses using high-throughput methodologies allow a deeper understanding of biological functions in different cell types/tissues. The present study provides an RNA-seq profiling of human sperm mRNAs and lncRNAs (messenger and...
Lysophosphatidic acid improves oocyte quality during IVM by activating the ERK1/2 pathway in cumulus cells and oocytes [0.03%]
溶血磷脂酸通过激活卵丘细胞和卵母细胞的ERK1 / 2通路改善体外成熟（IVM）过程中的卵母质量
Yerong Ma,Weijie Yang,Peipei Ren et al.
Yerong Ma et al.
Oocyte IVM technology is an option for fertility preservation in some groups of patients, such as those with polycystic ovary syndrome, patients with ovarian hyperstimulation syndrome, and for patients with cancer. However, the developmenta...
Oocyte-secreted factors strongly stimulate sFRP4 expression in human cumulus cells [0.03%]
卵母细胞分泌因子可强烈刺激人卵丘细胞中sfrp4的表达
Sahar Esfandyari,Nicola J Winston,Michelle A Fierro et al.
Sahar Esfandyari et al.
Secreted frizzled-related protein-4 (SFRP4) belongs to a family of soluble ovarian-expressed proteins that participate in female reproduction, particularly in rodents. In humans, SFRP4 is highly expressed in cumulus cells (CCs). However, th...
Comparative Study
Molecular human reproduction. 2021 May 29;27(6):gaab031. DOI:10.1093/molehr/gaab031 2021
Excess fibronectin 1 participates in pathogenesis of pre-eclampsia by promoting apoptosis and autophagy in vascular endothelial cells [0.03%]
过量纤连蛋白1通过促进血管内皮细胞凋亡和自噬参与子痫前期发病机制
Haiying Wu,Kan Liu,Jingli Zhang
Haiying Wu
Plasma fibronectin 1 (FN1) levels are elevated in individuals with pre-eclampsia (PE), which may be applied as a possible b marker for vascular endothelial injury during PE. In the present study, the possible role of FN1 in the pathogenesis...
In the mouse, prostaglandin D2 signalling protects the endometrium against adenomyosis [0.03%]
在小鼠中，前列腺素D2信号传导可保护子宫内膜免受腺肌症侵害
Pascal Philibert,Stéphanie Déjardin,Nelly Pirot et al.
Pascal Philibert et al.
Adenomyosis is characterised by epithelial gland and mesenchymal stroma invasion of the uterine myometrium. Adenomyosis is an oestrogen-dependent gynaecological disease in which a number of factors, such as inflammatory molecules, prostagla...
Duo Zhang,Wu-Jian Huang,Guo-Yong Chen et al.
Duo Zhang et al.
Acephalic spermatozoa syndrome (ASS) is a rare teratozoospermia that leads to male infertility. Previous work suggested a genetic origin. Variants of Sad1 and UNC84 domain containing 5 (SUN5) are the main genetic cause of ASS; however, its ...
Transfer- or 'transmission'-RNA fragments? The roles of tsRNAs in the reproductive system [0.03%]
转移RNA片段？tsRNAs在生殖系统中的作用
Hui-Min Li,Xia Tan,Shun Zhang et al.
Hui-Min Li et al.
Transfer-RNAs (tRNAs) help ribosomes decode mRNAs and synthesize proteins; however, tRNA fragments produced under certain conditions, known as tRNA-derived small RNAs (tsRNAs), have been found to play important roles in pathophysiological p...