Dynamics of extracellular vesicle-coupled microRNAs in equine follicular fluid associated with follicle selection and ovulation [0.03%]
与卵泡选择和排卵相关的马卵泡液中微囊耦联microRNAs的动态变化规律
Samuel Gebremedhn,Ahmed Gad,Ghassan M Ishak et al.
Samuel Gebremedhn et al.
Innumerable similarities in reproductive cyclicity and hormonal alterations highlight the considerable utility of the mare to study aspects of follicular dynamics and reproductive function in view of the largely constricted, human research ...
Basolateral secretions of human endometrial epithelial organoids impact stromal cell decidualization [0.03%]
人子宫内膜上皮类器官的基底外侧分泌物影响间质细胞蜕膜化
Harriet C Fitzgerald,Andrew M Kelleher,Chaman Ranjit et al.
Harriet C Fitzgerald et al.
Uterine glands and, by inference, their secretions impact uterine receptivity, blastocyst implantation, stromal cell decidualization, and placental development. Changes in gland function across the menstrual cycle are primarily governed by ...
Testis-specific actin-like 7A (ACTL7A) is an indispensable protein for subacrosomal-associated F-actin formation, acrosomal anchoring, and male fertility [0.03%]
睾丸特异性肌动蛋白样7A（ACTL7A）是次顶体相关F-肌动蛋白形成、顶体固定和雄性生育力所必需的蛋白质
P Ferrer,S Upadhyay,M Ikawa et al.
P Ferrer et al.
Formation of the acrosome during spermiogenesis is an essential process for creating fertilization-competent sperm. Of the numerous aspects required for acrosome biogenesis, adherence of the acrosomal outer membrane to the nuclear surface i...
MALDI mass spectrometry imaging shows a gradual change in the proteome landscape during mouse ovarian folliculogenesis [0.03%]
基质辅助激光解析电离飞行时间质谱成像技术描绘小鼠卵泡发育过程中蛋白质组变化特征地图
Giulia Fiorentino,Andrew Smith,Giovanna Nicora et al.
Giulia Fiorentino et al.
Our knowledge regarding the role proteins play in the mutual relationship among oocytes, surrounding follicle cells, stroma, and the vascular network inside the ovary is still poor and obtaining insights into this context would significantl...
Multiomics approach to profiling Sertoli cell maturation during development of the spermatogonial stem cell niche [0.03%]
多组学方法分析精子干细胞龛发育过程中支持细胞的成熟过程
A L Voigt,R Dardari,N L M Lara et al.
A L Voigt et al.
Spermatogonial stem cells (SSCs) are the basis of spermatogenesis, a complex process supported by a specialized microenvironment, called the SSC niche. Postnatal development of SSCs is characterized by distinct metabolic transitions from pr...
Men who inject opioids exhibit altered tRNA-Gly-GCC isoforms in semen [0.03%]
注射型阿片类药物使用者的精液中tRNA-Gly-GCC异构体出现异常变化
Germán Gornalusse,Ryan M Spengler,Erin Sandford et al.
Germán Gornalusse et al.
In addition to their role in protein translation, tRNAs can be cleaved into shorter, biologically active fragments called tRNA fragments (tRFs). Specific tRFs from spermatocytes can propagate metabolic disorders in second generations of mic...
Preconception paternal alcohol exposure decreases IVF embryo survival and pregnancy success rates in a mouse model [0.03%]
孕前父系酒精暴露会降低小鼠模型中IVF胚胎存活率和妊娠成功率
Alexis N Roach,Katherine N Zimmel,Kara N Thomas et al.
Alexis N Roach et al.
Increasingly, couples struggling with fertility turn to assisted reproductive techniques, including IVF, to have children. Despite the demonstrated influence of periconception male health and lifestyle choices on offspring development, stud...
Comprehensive molecular analysis identifies eight novel variants in XY females with disorders of sex development [0.03%]
全面分子分析识别了XY女性性发育障碍中的八个新变异基因
Vinayak Kulkarni,Selvaa Kumar Chellasamy,Somprakash Dhangar et al.
Vinayak Kulkarni et al.
Disorders of sex development (DSD) are a group of clinical conditions with variable presentation and genetic background. Females with or without development of secondary sexual characters and presenting with primary amenorrhea (PA) and a 46...
Pre-implantation mouse embryo movement under hormonally altered conditions [0.03%]
激素改变条件下前植入期小鼠胚胎的运动方式
Hannah Lufkin,Diana Flores,Zachary Raider et al.
Hannah Lufkin et al.
Pre-implantation embryo movement is crucial to pregnancy success, but the role of ovarian hormones in modulating embryo movement is not understood. We ascertain the effects of altered hormonal environment on embryo location using two delaye...
WDR87 interacts with CFAP47 protein in the middle piece of spermatozoa flagella to participate in sperm tail assembly [0.03%]
WDR87与精子鞭毛中段的CFAP47蛋白相互作用参与精子尾部组装过程
Hong-Qing Liao,Zi-Yi Guo,Li-Hua Huang et al.
Hong-Qing Liao et al.
Spermatogenesis is a complex process that includes spermatogonia self-renewal, spermatocyte meiosis and spermatozoa assembly. Recent studies have revealed that WD40-repeat domain-containing (WDR) proteins play important roles in spermatocyt...