Dydrogesterone exerts endothelial anti-inflammatory actions decreasing expression of leukocyte adhesion molecules [0.03%]
地drogerolem对血管内皮的抗炎作用通过减少白细胞粘附分子表达来实现
Xiao-Dong Fu,Silvia Garibaldi,Santosh Gopal et al.
Xiao-Dong Fu et al.
Clinical observations and basic studies show that progesterone and progestins have a variable influence on endothelial function. Dydrogesterone (DG) is a widely used progestin, but its endothelial actions have not been thoroughly assessed. ...
Developmentally regulated IL6-type cytokines signal to germ cells in the human fetal ovary [0.03%]
人胎儿卵巢中发育调节的IL6型细胞因子向生殖细胞信号转导
Sharon L Eddie,Andrew J Childs,Henry N Jabbour et al.
Sharon L Eddie et al.
Fetal ovarian development and primordial follicle formation are imperative for adult fertility in the female. Data suggest the interleukin (IL)6-type cytokines, leukaemia inhibitory factor (LIF), IL6, oncostatin M (OSM) and ciliary neurotro...
NLRP7 and the genetics of post-molar choriocarcinomas in Senegal [0.03%]
NLRP7与塞内加尔产后胎盘部位滋养细胞肿瘤的遗传学关系
Rima Slim,Philippe Coullin,Ange-Lucien Diatta et al.
Rima Slim et al.
Gestational choriocarcinomas are malignant tumors of trophoblastic cells that affect 5-25% of women with sporadic hydatidiform moles (HMs) depending on countries and studies. Nucleotide binding and oligomerization domain-like receptor prote...
Replacement of calcium for strontium in hamster sperm incubation media: effect on sperm function [0.03%]
钙替代培养液中的锶对精子功能的影响
Sandra Bachmann,Renata J Menéndez-Helman,Karina Zitta et al.
Sandra Bachmann et al.
Calcium (Ca(2+)) is an absolute requirement for a decisive sperm function event: the acrosome reaction (AR). Physiologically, sperm capacitation is a prerequisite for this specialized exocytosis and both events are intimately related. In an...
T W Kelsey,R A Anderson,P Wright et al.
T W Kelsey et al.
Human ovarian physiology is still poorly understood, with the factors and mechanisms that control initiation of follicular recruitment and loss remaining particularly unclear. Conventional hypothesis-led studies provide new data, results an...
Signalling pathways mediating specific synergistic interactions between GDF9 and BMP15 [0.03%]
GDF9和BMP15之间特异协同作用的信号转导途径
David G Mottershead,Lesley J Ritter,Robert B Gilchrist
David G Mottershead
Growth differentiation factor 9 (GDF9) and bone morphogenetic protein 15 (BMP15) are two proteins selectively expressed in the oocyte which are essential for normal fertility. Both of these proteins are members of the transforming growth fa...
Association of mutations in the zona pellucida binding protein 1 (ZPBP1) gene with abnormal sperm head morphology in infertile men [0.03%]
人类ZPBP1基因突变与男性不孕患者精子头形态异常的关系
Alexander N Yatsenko,Derek S O&#x;Neil,Angshumoy Roy et al.
Alexander N Yatsenko et al.
Nearly 7% of men are afflicted by male infertility worldwide, and genetic factors are suspected to play a significant role in the majority of these patients. Although sperm morphology is an important parameter measured in the semen analysis...
Uterine transplantation research: laboratory protocols for clinical application [0.03%]
子宫移植研究：用于临床应用的实验室规范
C Díaz-García,L Johannesson,A Enskog et al.
C Díaz-García et al.
The aim of this review is to summarize the state-of the-art methods that are used in clinical organ transplantation today, as well as the major findings of recent experimental uterus transplantation (UTx) research regarding organ donation/r...
Is galectin-1 a trigger for trophoblast cell fusion?: the MAP-kinase pathway and syncytium formation in trophoblast tumour cells BeWo [0.03%]
GALECTIN-1诱导滋养细胞融合吗？MAPK途径和BeWo肿瘤细胞合体形成关系的初步研究
Isabelle Fischer,Maja Weber,Christina Kuhn et al.
Isabelle Fischer et al.
Galectin-1 (gal-1), a member of the mammalian β-galactoside-binding proteins, exerts biological effects by recognition of glycan ligands, including those involved in cell adhesion and growth regulation. In a previous study, we demonstrated...
Cleavage of rRNA ensures translational cessation in sperm at fertilization [0.03%]
受精时rRNA的切割可确保精子翻译终止
G D Johnson,E Sendler,C Lalancette et al.
G D Johnson et al.
Intact ribosomal RNAs (rRNAs) comprise the majority of somatic transcripts, yet appear conspicuously absent in spermatozoa, perhaps reflecting cytoplasmic expulsion during spermatogenesis. To discern their fate, total RNA retained in mature...