Fertility in transgender and gender diverse people: systematic review of the effects of gender-affirming hormones on reproductive organs and fertility [0.03%]
性别重置激素对生殖器官和生育力的影响： transgender 和性别多样性人群的生育系统综述
C De Roo,F Schneider,T H R Stolk et al.
C De Roo et al.
Background: Transgender and gender diverse (TGD) people seek gender-affirming care at any age to manage gender identities or expressions that differ from their birth gender. Gender-affirming hormone treatment (GAHT) and g...
Arne S Sunde,Madelon van Wely
Arne S Sunde
Development and validation of a gonadotropin dose selection model for optimized ovarian stimulation in IVF/ICSI: an individual participant data meta-analysis [0.03%]
促性腺激素剂量选择模型的开发和验证 用于IVF/ICSI优化卵巢刺激：个体患者数据的荟萃分析
Nienke Schouten,Rui Wang,Helen Torrance et al.
Nienke Schouten et al.
Background: The ovarian response to gonadotropin stimulation varies widely among women, and could impact the probability of live birth as well as treatment risks. Many studies have evaluated the impact of different gonado...
The epigenetic approach of varicocele: a focus on sperm DNA and m6A-RNA methylation [0.03%]
精索静脉曲张的表观遗传学研究进展：以精子DNA和m6A-RNA甲基化为重点
Nushin Naderi,Marziyeh Tavalaee,Mohammad Hossein Nasr-Esfahani
Nushin Naderi
Background: Varicocele is an abnormal dilation and torsion of the pampiniform venous plexus in the scrotum due to venous reflux, primarily affecting the left side. It affects 15% of men and is a prevalent contributor to m...
The modeling of human implantation and early placentation: achievements and perspectives [0.03%]
人类着床和早期胎盘发育的建模：成果与展望
Tanya Dimova,Marina Alexandrova,Ivaylo Vangelov et al.
Tanya Dimova et al.
Background: Successful implantation is a critical step for embryo survival. The major losses in natural and assisted human reproduction appeared to occur during the peri-implantation period. Because of ethical constraints...
A systematic review and meta-analysis of double trophectoderm biopsy and/or cryopreservation in PGT: balancing the need for a diagnosis against the risk of harm [0.03%]
系统性回顾和荟萃分析：囊胚第二次滋养层活检与/或冷冻保存对胚胎种植前遗传学检测的影响——诊断需求与风险并重
Letizia Li Piani,Pasquale Petrone,Mariafrancesca Brutto et al.
Letizia Li Piani et al.
Background: To prevent the transfer of embryos affected by monogenic conditions and/or chromosomal defects, preimplantation genetic testing (PGT) requires trophectoderm biopsy and cryopreservation. In 2-6% of biopsies, th...
Functional hypothalamic amenorrhoea and polycystic ovarian morphology: a narrative review about an intriguing association [0.03%]
功能性下丘脑闭经与多囊卵巢形态：一种引人深思的关联——叙事综述
Johannes Ott,Geoffroy Robin,Marlene Hager et al.
Johannes Ott et al.
Background: Functional hypothalamic amenorrhoea (FHA) is responsible for 20-35% of all cases of secondary amenorrhoea and, thus, is the second most common cause of secondary amenorrhoea after polycystic ovary syndrome (PC...
Infertility treatment and offspring blood pressure-a systematic review and meta-analysis [0.03%]
关于不孕治疗与后代血压关系的系统评价和网络 meta 分析
Edwina H Yeung,Ian R Trees,Priscilla K Clayton et al.
Edwina H Yeung et al.
Background: Studies have inconsistently observed that children conceived by IVF or ICSI have higher blood pressure compared to children not conceived by these ARTs. ...
Misung Jo,Mats Brännström,James W Akins et al.
Misung Jo et al.
Background: Successful ovulation is essential for natural conception and fertility. Defects in the ovulatory process are associated with various conditions of infertility or subfertility in women. However, our understandi...
Evaluating the diagnostic accuracy of androgen measurement in polycystic ovary syndrome: a systematic review and diagnostic meta-analysis to inform evidence-based guidelines [0.03%]
评估多囊卵巢综合征雄激素检测诊断准确性：系统评价和诊断性Meta分析以制定循证指南
Asmamaw Demis Bizuneh,Anju E Joham,Helena Teede et al.
Asmamaw Demis Bizuneh et al.
Background: Biochemical hyperandrogenism is a hallmark and diagnostic feature of polycystic ovary syndrome (PCOS). However, the most accurate androgen measurement for assessing biochemical hyperandrogenism in PCOS diagnos...