Assessing the reproductive lifespan of female cancer survivors using AMH: a meta-synthesis of longitudinal studies [0.03%]
基于抗缪勒管激素的女性癌症幸存者的生殖寿命评估:纵向研究的meta分析合成
Neerujah Balachandren,Stavroula L Kastora,Richard A Anderson et al.
Neerujah Balachandren et al.
Background: Anti-Müllerian hormone (AMH) is widely used to assess gonadotoxicity related to anti-cancer treatments and to measure ovarian function in cancer survivors. The extent of AMH decline across malignancies and tr...
Post-translational modification of proteins in the human testis development pathway [0.03%]
人类睾丸发育途径中的蛋白质修饰Modification of proteins in the human testis development pathway
Firman P Idris,Lucas G A Ferreira,Brendan Houston et al.
Firman P Idris et al.
Background: The foetal testes produce the androgens necessary to masculinise the developing embryo and support the maturation of germ cells, that will eventually develop into sperm, thus ensuring future reproductive capac...
Clinical outcomes of Day-7 blastocysts: a systematic review and meta-analysis [0.03%]
第7天卵裂期胚胎的临床结局:系统评价和荟萃分析
Julie Firmin,Bastien Ducreux,Haitam Saidessalam et al.
Julie Firmin et al.
Background: Extended embryo culture beyond Day-6 remains controversial. While a small subset of embryos reaches the blastocyst stage on Day-7, their developmental competence and reproductive potential remain uncertain. Da...
Mapping ovarian cellular and molecular landscape across the lifespan of women: a scoping review [0.03%]
卵巢细胞和分子生命图谱的绘制:综述性质的研究
Darina Obukhova,Marina Loid,Marieke Schor et al.
Darina Obukhova et al.
Background: With growing interest in ART, fertility preservation, and postmenopausal health of women, reproductive medicine is increasingly focused on characterizing oocytes and ovarian tissue composition, as well as unde...
Clinical outcomes and euploidy rates of embryos derived from zygotes with nonpronuclear (0PN) and monopronuclear (1PN) in IVF or ICSI cycles: a systematic review and meta-analysis [0.03%]
非成熟卵子衍生胚胎的临床结局及整倍体率:系统评价和荟萃分析
Hoi Wing Chan,Chi Chiu Wang,David Yiu Leung Chan
Hoi Wing Chan
Background: During routine fertilization checks, the presence of two pronuclei (2PN) with two polar bodies is generally regarded as normal fertilization. Nonpronuclear (0PN) zygotes often suggest failed fertilization, but...
Sperm mitochondrial DNA copy number: a marker of male fertility and reproductive success [0.03%]
精子线粒体DNA拷贝数:男性生育力和生殖成功的标志
Savni Sawant,Jeffrey M Mann,J Richard Pilsner
Savni Sawant
Background: Sperm mitochondrial DNA copy number (mtDNAcn) has emerged as a promising biomarker of sperm health, providing molecular insight beyond what is captured by standard semen analysis. Elevated sperm mtDNAcn has be...
Embryo-derived extracellular vesicles and their potential as biomarkers for embryo quality during IVF: a systematic review [0.03%]
胚胎源性外泌体及其作为IVF中胚胎质量生物标志物的潜力:系统评价
Genevieve Boom,Vanessa Jordan,Lawrence W Chamley et al.
Genevieve Boom et al.
Background: Over the past decade, extracellular vesicles (EVs) released from embryos have received increasing attention for their potential role in influencing embryo-maternal communication events during implantation. Sev...
Endometriosis and ovarian cancer: epidemiological evidence, molecular insights, and clinical decision-making [0.03%]
子宫内膜异位症与卵巢癌:流行病学证据、分子认识和临床决策
Umberto Leone Roberti Maggiore,Michele Vignali,Marina Kvaskoff et al.
Umberto Leone Roberti Maggiore et al.
Endometriosis, particularly ovarian endometrioma, is associated with a 2-fold increased risk of ovarian cancer (OC), especially the clear cell and endometrioid subtypes. However, the absolute lifetime risk of OC in women with endometriosis ...
Maternal genetic variants associated with aneuploid conception: a narrative review [0.03%]
与非整倍体受精相关的母系遗传变异:综述式研究
Siyao Ha,Wenyi Liu,Ping Yuan et al.
Siyao Ha et al.
Background: Human aneuploid conception, a leading cause of infertility, pregnancy loss, and congenital disorders (e.g. Down's syndrome), arises from errors in chromosome segregation during oocyte meiosis or embryonic mito...
Iron overload disorders in adults: a comprehensive review of gonadal function, reproductive, and sexual health [0.03%]
成人铁负荷过重紊乱:全面回顾性腺功能、生殖和性健康状况
Francesco Carlomagno,Marta Tenuta,Andrea Sansone et al.
Francesco Carlomagno et al.
Background: Iron overload (IO) disorders, including thalassaemias, hereditary haemochromatosis, and transfusion-dependent anaemias, represent a growing clinical challenge with widespread systemic implications. Reproductiv...