DNA damage in preimplantation embryos and gametes: specification, clinical relevance and repair strategies [0.03%]
胚胎和配子中的DNA损伤：规定，临床意义及修复策略
Richard Musson,Łukasz Gąsior,Simona Bisogno et al.
Richard Musson et al.
Background: DNA damage is a hazard that affects all cells of the body. DNA-damage repair (DDR) mechanisms are in place to repair damage and restore cellular function, as are other damage-induced processes such as apoptosi...
The putative roles of FSH and AMH in the regulation of oocyte developmental competence: from fertility prognosis to mechanisms underlying age-related subfertility [0.03%]
卵子发育潜能调控中FSH和AMH的假定作用：从生育预后到年龄相关性不孕机制
Jose Buratini,Thaisy Tino Dellaqua,Mariabeatrice Dal Canto et al.
Jose Buratini et al.
Background: Fertility loss during female ageing is associated with increasing basal FSH and decreasing anti-Müllerian hormone (AMH) concentrations, together with compromised oocyte quality, presumably due to increased ox...
Obstetric and perinatal outcomes of singleton pregnancies after blastocyst-stage embryo transfer compared with those after cleavage-stage embryo transfer: a systematic review and cumulative meta-analysis [0.03%]
囊胚移植与卵裂期胚胎移植的单胎妊娠围生期结局：系统评价和累计meta分析
Nicola Marconi,Christopher Patrick Allen,Siladitya Bhattacharya et al.
Nicola Marconi et al.
Background: Extended embryo culture to blastocyst stage is widely used in IVF and is the default strategy in most clinics. The last decade has witnessed a growing interest in obstetric-perinatal outcomes following blastoc...
Mei Wang,Ling Zeng,Ping Su et al.
Mei Wang et al.
Background: Autophagy is an intracellular catabolic process of degrading and recycling proteins and organelles to modulate various physiological and pathological events, including cell differentiation and development. Eme...
Chances of pregnancy and live birth among women undergoing conservative management of early-stage endometrial cancer: a systematic review and meta-analysis [0.03%]
早期子宫内膜癌患者保守治疗后怀孕及活产的几率：系统评价和网状Meta分析
Erica Herrera Cappelletti,Jonas Humann,Rafael Torrejón et al.
Erica Herrera Cappelletti et al.
Background: Endometrial cancer is common and usually occurs after menopause, but the number of women diagnosed during reproductive age is increasing. The standard treatment including hysterectomy is effective but causes a...
The role of cellular senescence in female reproductive aging and the potential for senotherapeutic interventions [0.03%]
细胞衰老在女性生殖老化中的作用及Senotherapy干预的潜力
Laura Secomandi,Michela Borghesan,Michael Velarde et al.
Laura Secomandi et al.
Background: Advanced maternal age is associated with decreased oocyte quantity and quality as well as uterine and placental dysfunctions. These changes lead to infertility, pregnancy complications and birth defects in the...
Barriers and facilitators for the inclusion of fertility care in reproductive health policies in Africa: a qualitative evidence synthesis [0.03%]
在非洲将生育护理纳入生殖健康政策的障碍和促进因素：定性证据综合
Anna Afferri,Haddijatou Allen,Andrew Booth et al.
Anna Afferri et al.
Background: Infertility affects over 50 million couples worldwide and impacts people's social and emotional wellbeing. In low- and middle-income countries, particularly across Africa, the inclusion of fertility care into ...
Novel microarchitecture of human endometrial glands: implications in endometrial regeneration and pathologies [0.03%]
人类子宫内膜腺体的新颖微体系结构：在子宫内膜再生及疾病的含义
Nicola Tempest,Christopher J Hill,Alison Maclean et al.
Nicola Tempest et al.
Background: Human endometrium remains a poorly understood tissue of the female reproductive tract. The superficial endometrial functionalis, the site of embryo implantation, is repeatedly shed with menstruation, and the s...
Chao Yang,Peng Li,Zheng Li
Chao Yang
Background: Infertility affects 15% of men and contributes to nearly half of all cases of infertility. Infertile men usually have impaired spermatogenesis, presenting as azoospermia or various degrees of asthenospermia an...
Effects of different frozen embryo transfer regimens on abnormalities of fetal weight: a systematic review and meta-analysis [0.03%]
不同的冻胚移植方案对胎儿体重异常的影响：系统评价和荟萃分析
Kendal Rosalik,Samantha Carson,Justin Pilgrim et al.
Kendal Rosalik et al.
Background: Reported increases in maternal and perinatal morbidity (including macrosomia, large for gestational age (LGA), cesarean section, hemorrhage and hypertensive disorders of pregnancy) following frozen embryo tran...