Biomechanical forces and signals operating in the ovary during folliculogenesis and their dysregulation: implications for fertility [0.03%]
卵泡发育过程中卵巢内的生物力学作用力及信号及其失调对生育的影响
Giulia Fiorentino,Danilo Cimadomo,Federica Innocenti et al.
Giulia Fiorentino et al.
Background: Folliculogenesis occurs in the highly dynamic environment of the ovary. Follicle cyclic recruitment, neo-angiogenesis, spatial displacement, follicle atresia and ovulation stand out as major events resulting f...
Emilio Francés-Herrero,Rosalba Lopez,Mats Hellström et al.
Emilio Francés-Herrero et al.
Background: To provide the optimal milieu for implantation and fetal development, the female reproductive system must orchestrate uterine dynamics with the appropriate hormones produced by the ovaries. Mature oocytes may ...
Administration of growth hormone improves endometrial function in women undergoing in vitro fertilization: a systematic review and meta-analysis [0.03%]
生长激素改善体外受精妇女子宫内膜功能的系统评价和 Meta 分析
Yujie Shang,Minghua Wu,Ruohan He et al.
Yujie Shang et al.
Background: The positive effects of growth hormone (GH) on IVF are often attributed to improvements in oocyte and embryo quality. While emerging evidence emphasizes GH-induced improvements in the endometrium, these result...
BCL6, a key oncogene, in the placenta, pre-eclampsia and endometriosis [0.03%]
BCL6基因与胎盘、子痫前期和子宫内膜异位症的关系
Frank Louwen,Nina-Naomi Kreis,Andreas Ritter et al.
Frank Louwen et al.
Background: The key oncogene B-cell lymphoma 6 (BCL6) drives malignant progression by promoting proliferation, overriding DNA damage checkpoints and blocking cell terminal differentiation. However, its functions in the pl...
Tianli Yang,Jing Zhao,Feng Liu et al.
Tianli Yang et al.
Background: Obesity has now been recognized as a high-risk factor for reproductive health. Although remarkable advancements have been made in ART, a considerable number of infertile obese women still suffer from serial im...
Comparison of dietary and physical activity behaviors in women with and without polycystic ovary syndrome: a systematic review and meta-analysis of 39 471 women [0.03%]
与多囊卵巢综合征女性相比，未患该病的女性在饮食和身体活动行为方面存在差异：一项针对39471名女性的系统评价和meta分析研究
Maryam Kazemi,Joy Y Kim,Cynthia Wan et al.
Maryam Kazemi et al.
Background: Lifestyle (dietary and/or physical activity [PA]) modification is recommended as first-line therapy to manage polycystic ovary syndrome (PCOS). Current recommendations are based on healthy lifestyle practices ...
Meiotic recombination: insights into its mechanisms and its role in human reproduction with a special focus on non-obstructive azoospermia [0.03%]
减数重组：对非梗阻性无精子症中其机制及在人类繁殖作用的见解
Chunbo Xie,Weili Wang,Chaofeng Tu et al.
Chunbo Xie et al.
Background: Meiosis is an essential stage in the life cycle of sexually reproducing species, underlying formation of haploid gametes and serving as the basis of genetic diversity. A central mechanism of meiosis is recombi...
Morphological and morphokinetic associations with aneuploidy: a systematic review and meta-analysis [0.03%]
与非整倍体相关的影响形态和动力学的特征：系统评价和荟萃分析
Thomas Bamford,Amy Barrie,Sue Montgomery et al.
Thomas Bamford et al.
Background: A time lapse system (TLS) is utilized in some fertility clinics with the aim of predicting embryo viability and chance of live birth during IVF. It has been hypothesized that aneuploid embryos display altered ...
Ovarian stimulation strategies for intrauterine insemination in couples with unexplained infertility: a systematic review and individual participant data meta-analysis [0.03%]
不明原因不孕夫妇宫内人工授精的卵巢刺激策略：系统评价及个体参与者数据meta分析
J A Wessel,N A Danhof,R van Eekelen et al.
J A Wessel et al.
Background: Intrauterine insemination with ovarian stimulation (IUI-OS) is a first-line treatment for unexplained infertility. Gonadotrophins, letrozole and clomiphene citrate (CC) are commonly used agents during IUI-OS a...
Does hormonal therapy improve sperm retrieval rates in men with non-obstructive azoospermia: a systematic review and meta-analysis [0.03%]
激素治疗可提高非梗阻性无精子症患者获取精子率吗？一项系统评价和meta分析
Tharu Tharakan,Giovanni Corona,Daniel Foran et al.
Tharu Tharakan et al.
Background: The beneficial effects of hormonal therapy in stimulating spermatogenesis in patients with non-obstructive azoospermia (NOA) and either normal gonadotrophins or hypergonadotropic hypogonadism prior to surgical...