Jonathan M Samet,David B Richardson
Jonathan M Samet
The Nuclear Age spurred widespread mining of uranium for production of weapons and for nuclear power. The widespread mining of uranium, with historically limited control of radiation exposures, has resulted in high rates of lung cancer amon...
Summary of radiation effects on incidence of solid cancers in the Life Span Study of atomic bomb survivors: 1958-2009 [0.03%]
历山研究：1958-2009年原子弹幸存者患实体瘤发病率的辐射效应总结报告
Alina V Brenner,Hiromi Sugiyama,John Cologne et al.
Alina V Brenner et al.
This paper concludes the third comprehensive report on radiation effects on solid cancer incidence within the Life Span Study (LSS) cohort of Japanese atomic bomb survivors, adding 11 years of follow-up. Over 1958-2009, 22 538 solid cancer ...
Eight decades of research on the long-term health effects of radiation in atomic bomb survivors and their offspring [0.03%]
原子 bomb幸存者及其后代长期健康效应研究的八十年历程
Kenji Kamiya,Ritsu Sakata,Preetha Rajaraman
Kenji Kamiya
This year marks the 80th anniversary of the atomic bombings of Hiroshima and Nagasaki. Over the past eight decades, large-scale cohort studies of atomic bomb survivors and their offspring conducted by the Radiation Effects Research Foundati...
Joe W Gray,Andrew P Feinberg
Joe W Gray
Graphical Abstract Keywords: a-bomb survivors; epidemiology; epigenomics; genomics; radiation effects resea...
Symposium report-ethical and social considerations regarding return of secondary findings in atomic bomb survivors [0.03%]
伦理和社会方面关于返回二次发现在 atomic bomb 受害者中的考虑研讨会报告
Noriaki Yoshida,Douglas R Stewart,Arikuni Uchimura et al.
Noriaki Yoshida et al.
The Radiation Effects Research Foundation (RERF) conducts research on the health effects of atomic bomb (A-bomb) radiation, supported by the long-term cooperation of survivors and their children. In response to concerns from A-bomb survivor...
Genomic landscape of radiation-induced somatic mutations in a normal cell [0.03%]
辐射诱导的正常细胞体细胞性染色体突变的基因组景观
Yukiko Matsuda,Osamu Tanabe
Yukiko Matsuda
Atomic bomb survivors have been found to have an excess risk of late adverse effects, including leukemia, various solid cancers, and non-cancer diseases, depending on the dose of radiation exposure. Radiation-induced DNA damage can lead to ...
Harry M Cullings,Sachiyo Funamoto,Stephen D Egbert et al.
Harry M Cullings et al.
Studies of the health effects among Japanese atomic bomb survivors, including radiation-induced carcinogenesis, necessitate accurate radiation dose estimates for individual survivors from the Hiroshima and Nagasaki bombings. Efforts toward ...
Recent evolution of risk analyses in atomic bomb survivor studies: new methods and applications [0.03%]
近年原子弹受害者的风险分析的演变：新的方法和应用
John Cologne,Munechika Misumi,Hanna Lindner et al.
John Cologne et al.
Several decades ago a dramatic leap forward occurred in the development and application of statistical methods for modeling radiation risk at the Radiation Effects Research Foundation (RERF). Poisson regression analysis for grouped person-y...
MAPK3 Modulates Enhancer-Promoter Interactions of SKAP2 in Acute Myeloid Leukemia [0.03%]
MAPK3通过调节急性髓系白血病中SKAP2的增强子-启动子互作发挥促癌作用
Yanping Hu,Fang Chen,Tingjie Wang et al.
Yanping Hu et al.
The regulation of gene expression through chromatin architecture plays a critical role in acute myeloid leukemia (AML). In this study, the influence of MAPK3 on CTCF-mediated chromatin interactions in AML was examined, focusing on gene regu...
CarD-T: An Automated Pipeline for the Nomination and Analysis of Potential Human Carcinogens [0.03%]
CarD-T：一种潜在人类致癌物提名和分析的自动化流水线方法
Jamey O&#x;Neill,Gudur Ashrith Reddy,Nermeeta Dhillon et al.
Jamey O&#x;Neill et al.
The identification and classification of carcinogens is critical in cancer epidemiology, necessitating updated methodologies to manage the burgeoning biomedical literature. We introduce the Carcinogen Detection via Transformers (CarD-T) fra...