Subthalamic spatio-spectral-connectivity of psychiatric symptoms in Parkinson's disease [0.03%]
帕金森病的精神病症状的亚thalamic空间光谱连接性
Linbin Wang,Ying Zhao,Peng Huang et al.
Linbin Wang et al.
Psychiatric symptoms in Parkinson's disease (PD) are highly prevalent and challenging to treat. This study maps oscillatory neural activity to diverse psychiatric symptoms in PD, using resting-state subthalamic nucleus (STN) local field pot...
Amyloid-linked trajectories of cerebral hypoperfusion and dopamine loss in dementia with Lewy bodies [0.03%]
路易体痴呆中淀粉样蛋白相关的脑低灌注和多巴胺能损失的轨迹研究
Chan Wook Park,Yurim Choi,Hye Sun Lee et al.
Chan Wook Park et al.
Dementia with Lewy bodies (DLB) is clinically heterogeneous, and the evolutionary trajectories of cortical dysfunction, nigrostriatal dopaminergic degeneration, and amyloid accumulation, as well as the interactions among them, remain poorly...
Distinct roles of the human cuneiform and pedunculopontine nuclei in gait and freezing of gait [0.03%]
人形椎核和桥脑网状核在步态和冻结中的不同作用
Mathieu Yeche,Antoine Collomb-Clerc,Katia Lehongre et al.
Mathieu Yeche et al.
Freezing of gait (FOG) in Parkinson's disease (PD) is a major cause of disability, often resistant to dopaminergic therapy and deep brain stimulation (DBS). Its underlying neural mechanisms remain unclear. The mesencephalic locomotor region...
Revisiting multifocal motor neuropathy: mechanisms, diagnosis and future directions [0.03%]
多焦性运动神经病的再思考：机制、诊断及未来方向
Nicolas J Dubuisson,Yusuf A Rajabally,Clive Philips et al.
Nicolas J Dubuisson et al.
Multifocal Motor Neuropathy (MMN) is an immune-mediated, pure motor neuropathy characterized by slowly progressive, asymmetric limb weakness. It predominantly affects men in mid-adulthood and often presents with distal upper-limb weakness, ...
Reply: Interpreting early default mode network dysfunction across the Alzheimer's disease Spectrum [0.03%]
关于阿尔茨海默病谱系早期默认模式网络功能障碍的解读回复
David T Jones,Nick Corriveau-Lecavalier
David T Jones
Interpreting early default mode network dysfunction across the Alzheimer's disease spectrum [0.03%]
阿尔茨海默病谱系中默认模式网络早期功能障碍的解释
Forough Sodaei,Laust Vind Knudsen
Forough Sodaei
Treatment escalation after clinically silent MRI lesions in relapsing-remitting multiple sclerosis [0.03%]
复发缓解型多发性硬化症患者在磁共振检测到临床沉默病灶后的治疗升级措施
Cyrus Daruwalla,Courtney Kremler,Francesco Patti et al.
Cyrus Daruwalla et al.
Clinically silent MRI lesions occur frequently in people with relapsing-remitting multiple sclerosis (RRMS) despite disease modifying therapy (DMT). Guidelines only routinely recommend DMT escalation after multiple silent lesions, and adher...
Beyond distal arthrogryposis: refining the phenotypic landscape of PIEZO2-related disorders [0.03%]
PIEZO2相关疾病的表型特征再认识——超出远端关节挛缩症的范畴
Giuliana Capece,Maria Francesca Di Feo,Evgeniya Melnik et al.
Giuliana Capece et al.
Piezo2 channels are mechanosensors expressed in dorsal root ganglia and Merkel cells, and involved in proprioception and touch sensation. PIEZO2 pathogenic variants cause rare autosomal dominant and recessive disorders. Dominant forms inclu...
Bilateral gamma knife radiosurgery in severe essential tremor: a prospective trial [0.03%]
双边立体定向放射外科手术治疗严重原发性震颤：一项前瞻性的试验研究
Jean Régis,Valentin Mira,Serge Pinto et al.
Jean Régis et al.
In patients with medically refractory essential tremor, unilateral Gamma Knife radiosurgery (GKS) of the Ventral Intermedius Thalamic nucleus (VIM) is known to improve contralateral tremor with a good safety. Safety of staged bilateral GKS ...