Potential impact of functional biomolecules-enriched foods on human health: A randomized controlled clinical trial [0.03%]
富含功能活性生物分子食物对人体健康潜在影响的随机对照临床试验研究
Marco Tatullo,Benedetta Marrelli,Caterina Benincasa et al.
Marco Tatullo et al.
Naturally occurring milk compounds have recently been investigated for their health-promoting properties; in fact, their anti-microbial, immuno-modulatory, antioxidant and anti-thrombotic activities, have increasingly gained interest within...
Randomized Controlled Trial
International journal of medical sciences. 2022 Mar 6;19(3):563-571. DOI:10.7150/ijms.70435 2022
Loss-of-function Mutations K11E or E271K Lead to Novel Tumor Suppression, Implicate Nucleolar Helicase DDX24 Oncogenicity [0.03%]
功能丧失型突变K11E或E271K导致新型肿瘤抑制作用，暗示核仁解旋酶DDX24的致癌性
Xinglin Li,Xiaoyun Chen,Jiebing Gao et al.
Xinglin Li et al.
Purpose: Mutations (K11E or E271K) of DEAD-box RNA helicase 24 (DDX24) were related to multi-organ venous lymphatic malformation syndrome (MOVLD). However, the relationship between these mutations and DDX24-function still remains unknown. U...
miR-204-5p inhibits cell proliferation and induces cell apoptosis in esophageal squamous cell carcinoma by regulating Nestin [0.03%]
微RNA-204-5p通过调节巢蛋白抑制食管鳞癌细胞增殖并促进细胞凋亡
Honghe Luo,Weize Lv,Huayong Zhang et al.
Honghe Luo et al.
Esophageal cancer (EC) is a highly malignant gastrointestinal tumor, and esophageal squamous cell carcinoma (ESCC) is one of the most common histological types of EC. MicroRNAs (miRNAs) are small noncoding RNAs closely related to tumorigene...
Prognostic Factors of AL-PCMM and AL-MM: A Single-Center Retrospective Study [0.03%]
AL型原发性中枢神经系统淋巴瘤和继发于AL型MM的CNS受累的预后因素：单中心回顾性研究
Junhui Xu,Zhixiang Qiu,Miao Yan et al.
Junhui Xu et al.
Background: Patients with amyloid light-chain (AL) amyloidosis with a bone marrow plasma cell ratio > 10% (AL-PCMM) have a poorer prognosis than patients with AL amyloidosis with a bone marrow plasma cell ratio of
CEMIP as a potential biomarker and therapeutic target for breast cancer patients [0.03%]
CEMIP作为乳腺癌患者的潜在生物标志物和治疗靶点
Jinqi Xue,Xudong Zhu,Xinbo Qiao et al.
Jinqi Xue et al.
Purpose: We aimed to evaluate whether CEMIP plays any role in the survival outcome of breast cancer (BC) patients, as well as to explore the regulatory mechanism of CEMIP in BC. Methods: We evaluated the expression and prognostic effect of ...
Shanshan Feng,Fuqiang Song,Wenqiong Guo et al.
Shanshan Feng et al.
Hypertension, diabetes mellitus, and coronary artery disease are common comorbidities and dangerous factors for infection and serious COVID-19. Polymorphisms in genes associated with comorbidities may help observe susceptibility and disease...
Differential lipidomics of HK-2 cells and exosomes under high glucose stimulation [0.03%]
高糖刺激下HK-2细胞与外泌体差异脂质组学分析
Weidong Wang,Tingting Li,Zhijie Li et al.
Weidong Wang et al.
Abnormal cellular lipid metabolism has a very important role in the occurrence and progression of diabetic kidney disease (DKD). However, the lipid composition and differential expression by high glucose stimulation of renal tubular cells a...
A Novel Prognostic Predictor of Immune Microenvironment and Therapeutic Response in Kidney Renal Clear Cell Carcinoma based on Necroptosis-related Gene Signature [0.03%]
基于坏死性凋亡相关基因特征的肾透明细胞癌免疫微环境预后预测因子及治疗反应的新方法
Wenwei Chen,Wenfeng Lin,Liang Wu et al.
Wenwei Chen et al.
Background: Necroptosis, a cell death of caspase-independence, plays a pivotal role in cancer biological regulation. Although necroptosis is closely associated with oncogenesis, cancer metastasis, and immunity, there remains a lack of studi...
Upregulation of C/EBP Homologous Protein induced by ER Stress Mediates Epithelial to Myofibroblast Transformation in ADTKD-UMOD [0.03%]
由内质网应激诱导的C/EBP同源蛋白介导ADTKD-UMOD上皮成肌成纤维细胞转化
Dan Wang,Yagui Qiu,Jinjin Fan et al.
Dan Wang et al.
Autosomal dominant tubulointerstitial kidney disease due to UMOD mutations (ADTKD-UMOD) results in chronic interstitial nephritis, which gradually develops into end-stage renal disease. It is believed that the accumulation of mutant uromodu...
Skeletal muscle satellite cell-derived mesenchymal stem cells ameliorate acute alcohol-induced liver injury [0.03%]
骨骼肌卫星细胞源间充质干细胞改善急性酒精性肝损伤
Jae Sik Chung,Soonjae Hwang,Ju Eun Hong et al.
Jae Sik Chung et al.
Cultured human skeletal-muscle satellite cells have properties of mesenchymal stem cells (skeletal muscle satellite cell-derived mesenchymal stem cells, SkMSCs) and play anti-inflammatory roles by secreting prostaglandin E2 and hepatocyte g...