SJMHE1 protects against excessive iodine-induced pyroptosis in human thyroid follicular epithelial cells through a toll-like receptor 2-dependent pathway [0.03%]
SJMHE1通过TLR2依赖性途径保护人甲状腺滤泡上皮细胞免受过量碘诱导的pyroptosis侵害
Zhu Zhang,Jiameng Liu,Chaoming Mao et al.
Zhu Zhang et al.
To elucidate the effect of Schistosoma japonicum peptide (SJMHE1) on pyroptosis in thyroid follicular epithelial cells (TFCs) induced by excessive iodine and the potential mechanism, the effects of SJMHE1 were investigated in NaI-treated Nt...
The Emerging Portrait of Glial Cell Line-derived Neurotrophic Factor Family Receptor Alpha (GFRα) in Cancers [0.03%]
胶质细胞源性神经营养因子家族受体阿尔法(GFRα)在癌症中的作用初探
Qingshang Li,Zhijun Cao,Shuliang Zhao
Qingshang Li
Glial cell line-derived neurotrophic factor family receptor alpha (GFRα) members have been widely connected to the mechanisms contributing to cell growth, differentiation, cell migration and tissue maturation. Here we review GFRα biologic...
Expression of Membrane Bound O-Acyltransferase Domain Containing 7 after Myocardial Infarction and its Role in Lipid Metabolism in vitro [0.03%]
心肌梗死后膜结合O-酰基转移酶结构域蛋白7的表达及其体外脂代谢作用研究
Xiangdong Li,Zhiyuan Wang,Heyu Meng et al.
Xiangdong Li et al.
Background: Previous microarray analysis on peripheral blood leukocytes from three patients with acute myocardial infarction (AMI) showed that elevated expression of membrane bound o-acyltransferase domain containing 7(MBOAT7) relative to c...
Single-cell RNA Sequencing Uncovered the Involvement of an Endothelial Subset in Neutrophil Recruitment in Chemically Induced Rat Pulmonary Inflammation [0.03%]
单细胞RNA测序揭示了一种内皮亚群在化学诱导的大鼠肺部炎症中参与中性粒细胞募集的现象
Hong Huang,Ying Yang,Tingting Song et al.
Hong Huang et al.
There is growing support for the notion that chronic inflammation contributes to lung tumorigenesis, but the molecular and cellular basis underlying the protumorigenic effects of inflammation remains to be explored. 3-Methylcholanthrene and...
Efficacy and safety of endovenous laser ablation with the 1470 nm diode laser using a novel optical probe [0.03%]
一种新型光学探头的1470nm半导体激光血管内闭合的疗效及安全性评估研究
Karsten Hartmann,Patrick Gholam,Carmen Dietrich et al.
Karsten Hartmann et al.
Objectives: Outcome assessment of a novel optical fiber probe for the 1470 nm diode laser under real-world conditions. Methods: Prospective clinical pilot study in 10 patients undergoing endovenous laser ablation with a follow-up period of ...
Deficiency of Wnt10a causes female infertility via the β-catenin/Cyp19a1 pathway in mice [0.03%]
Wnt10a缺乏通过β-连环蛋白/Cyp19a1信号传导途径导致小鼠雌性不孕
Jia-He Zhang,Takashi Tasaki,Manabu Tsukamoto et al.
Jia-He Zhang et al.
Wnt signaling is relevant for a wide range of biological processes, including reproductive function. The function of Wnt10a in female fertility, however, remains obscure. In the present study, we explored the structure and function of the f...
Comprehensive analysis of circRNA expression profiles in rat cerebral cortex after moderate traumatic brain injury [0.03%]
脑外伤后环形RNA表达谱分析
Gang Li,Shaoping Li,Ruining Liu et al.
Gang Li et al.
Traumatic brain injury is a medical event of global concern, and a growing body of research suggests that circular RNAs can play very important roles in traumatic brain injury. To explore the functions of more novel and valuable circular RN...
Identification and validation of the N6-methyladenosine RNA methylation regulator ZC3H13 as a novel prognostic marker and potential target for hepatocellular carcinoma [0.03%]
识别并验证N6-甲基腺苷RNA甲基化调控因子ZC3H13作为肝细胞癌新型预后标志物及潜在治疗靶点的价值
Shuang Wu,Guifang He,Shihai Liu et al.
Shuang Wu et al.
N6-methyladenosine (m6A) RNA methylation has been implicated in various malignancies. This study aimed to identify prognostic signature based on m6A methylation regulators for hepatocellular carcinoma (HCC) and provide candidate targets for...
Paeoniflorin attenuates monocrotaline-induced pulmonary arterial hypertension in rats by suppressing TAK1-MAPK/NF-κB pathways [0.03%]
芍药苷通过抑制TAK1-MAPK / NF-κB信号通路缓解肺动脉高压小鼠模型的肺动脉高血压
Min Yu,Xuecheng Wu,Jingjing Wang et al.
Min Yu et al.
Pulmonary arterial hypertension (PAH) characterized by pulmonary vascular remodeling is a lethal disease. Paeoniflorin (PF) is a monoterpene glycoside with numerous beneficial functions, such as vasodilation, anti-inflammation and immunomod...
Visfatin Polymorphisms, Lifestyle Risk Factors and Risk of Oral Squamous Cell Carcinoma in a Cohort of Taiwanese Males [0.03%]
台湾男性人群中visfatin基因多态性、生活方式危险因素与口腔鳞癌发病风险的关联研究
Kwei-Jing Chen,Ming-Hong Hsieh,Yen-You Lin et al.
Kwei-Jing Chen et al.
Oral cancer is the eighth greatest generally diagnosed cancer amongst males worldwide and the fourth most generally malignancy amongst Taiwanese males. The pro-inflammatory adipocytokine visfatin promotes tumor growth. Elevated plasma visfa...