Risk of peripheral artery disease and stroke in migraineurs with or without aura: a nationwide population-based cohort study [0.03%]
偏头痛有先兆或无先兆与外周动脉疾病和卒中风险的关系——一项基于全国人群的队列研究
Wun-Zhih Siao,Chun-Hung Su,Yu-Hsiang Kuan et al.
Wun-Zhih Siao et al.
Background: Migraine is deemed a neurovascular disorder and there is growing evidence on the increased risk of cardiovascular disease, especially ischemic stroke, in patients with migraine. However the risk of peripheral artery disease (PAD...
Exosomes Derived from Glioma Cells under Hypoxia Promote Angiogenesis through Up-regulated Exosomal Connexin 43 [0.03%]
低氧诱导的胶质瘤细胞源外泌体通过上调缝隙连接蛋白43促进血管生成
Zhang-Jian Yang,Qiu-Chen Bi,Li-Jun Gan et al.
Zhang-Jian Yang et al.
Glioblastoma multiform (GBM) is a highly aggressive primary brain tumor. Exosomes derived from glioma cells under a hypoxic microenvironment play an important role in tumor biology including metastasis, angiogenesis and chemoresistance. How...
Machine Learning-based Correlation Study between Perioperative Immunonutritional Index and Postoperative Anastomotic Leakage in Patients with Gastric Cancer [0.03%]
基于机器学习的胃癌患者围手术期免疫营养指数与术后吻合口漏关联性研究
Xuanyu Liu,Su Lei,Qi Wei et al.
Xuanyu Liu et al.
Backgrounds: The immunonutritional index showed great potential for predicting postoperative complications in various malignant diseases, while risk assessment based on machine learning (ML) methods is becoming popular in clinical practice....
Catechin-7- O-α-L-rhamnopyranoside can reduce α-MSH-induced melanogenesis in B16F10 melanoma cells through competitive inhibition of tyrosinase [0.03%]
儿茶素-7-O-α-L-半乳糖吡喃糖苷通过与酪氨酸竞争抑制黑色素合成诱导剂诱导的黑色素瘤细胞黑化反应
Taehyeok Hwang,Hyo Jung Lee,Woo Sung Park et al.
Taehyeok Hwang et al.
Although melanogenesis is a defense mechanism against ultraviolet (UV)-induced skin damage, abnormally excessive melanin production causes pigmentation disorders. Tyrosinase, as a key factor for melanin synthesis, plays an important role in...
Curcumin enhances p-cresyl sulfate-induced cytotoxic effects on renal tubular cells [0.03%]
姜黄素增强对羟基苯甲硫醚诱导的肾小管细胞毒性作用
Chyou-Wei Wei,Tsai-Kun Wu,Shu-Cing Wu et al.
Chyou-Wei Wei et al.
Indoxyl sulfate (IS) and p-cresyl sulfate (PCS), protein-bound uremic toxins, can induce oxidative stress and cause renal disease progression. However, the different cytotoxic effects on renal cells between IS and PCS are not stated. Due to...
Rotenone, an environmental toxin, causes abnormal methylation of the mouse brain organoid's genome and ferroptosis [0.03%]
环境毒素罗tenone导致小鼠脑类器官基因组异常甲基化和铁死亡
Yongyi Huang,Xin Liu,Ya Feng et al.
Yongyi Huang et al.
More and more reports have pointed out that rotenone, as an insecticide, has high neurotoxicity and reproductive toxicity to livestock and mammals. As a highly physiological correlation system of internal organs, quasi-organs have great pot...
Hao Chen,Liangfu Zhou
Hao Chen
Ischemic stroke is one of the leading causes of death and disability. Ischemia triggers a cascade of events leading to cell death and cerebral infarction. Mesenchymal stem cell (MSC) therapy is a promising treatment modality to promote the ...
[6]-Gingerol induces Caspase-Dependent Apoptosis in Bladder Cancer cells via MAPK and ROS Signaling [0.03%]
姜醇通过MAPK和ROS信号诱导膀胱癌细胞凋亡
Na Ri Choi,Woo-Gyun Choi,Min Ji Kwon et al.
Na Ri Choi et al.
The anti-cancer effects of [6]-gingerol ([6]-GIN), the main active polyphenol of ginger (Zingiber officinale), were investigated in the human bladder cancer cell line 5637. [6]-GIN inhibited cell proliferation, increased sub‑G1 phase ratio...
A one-year follow-up study on dynamic changes of leukocyte subsets and virus-specific antibodies of patients with COVID-19 in Sichuan, China [0.03%]
中国四川新冠肺炎患者一年的随访研究：免疫细胞动态变化及特异性抗体水平调查分析
Renjie Xu,Bennan Zhao,Lijuan Lan et al.
Renjie Xu et al.
Background: SARS-CoV-2 infection causes immune response and produces protective antibodies, and these changes may persist after patients discharged from hospital. Methods: This study conducted a one-year follow-up study on patients with COV...
The value of quantitative magnetic resonance imaging signal intensity in distinguishing between spinal meningiomas and schwannomas [0.03%]
定量磁共振信号强度鉴别脊柱脑膜瘤与施万细胞瘤的价值
Nguyen Duy Hung,Le Thanh Dung,Dang Khanh Huyen et al.
Nguyen Duy Hung et al.
Background: Prior studies have suggested a number of the subjective visual characteristics that help distinguish between spinal meningiomas and schwannomas on magnetic resonance imaging and computed tomography; however, objective quantifica...