The application of hyaluronic acid-containing artificial tears on the ocular surface of children receiving orthokeratology contact lens treatment [0.03%]
透明质酸人工泪液在正向离焦角膜接触镜治疗儿童近视中应用的临床研究
Chia-Yi Lee,Shun-Fa Yang,Jing-Yang Huang et al.
Chia-Yi Lee et al.
Purpose: The purpose of this study was to compare the effects of the application of hyaluronic acid (HA)-containing artificial tears and non-HA artificial tears on the ocular surface of children receiving orthokeratology contact lens treatm...
Role of Metabolic Abnormalities During the Progression of Chronic Kidney Disease and Preventive Strategies [0.03%]
代谢异常在慢性肾脏病进展中的作用及预防策略
Dongqing Zha,Ping Gao,Xiaoyan Wu
Dongqing Zha
Chronic kidney disease (CKD) is characterized by persistent renal impairment or dysfunction that lasts for at least 3 months, and typically has a progressive and irreversible trajectory. The increasing prevalence of metabolic disorders, suc...
miR-548aj-3p and miR-3127-3p suppress RANKL-facilitated inflammatory cytokines and catabolic factor in osteoarthritis and rheumatoid arthritis [0.03%]
miR-548aj-3p和miR-3127-3p通过抑制RANKL促炎细胞因子和分解代谢因子的表达抑制骨关节炎和类风湿性关节炎的发展
Yu-Han Wang,Chin-Horng Su,Li-Chai Chen et al.
Yu-Han Wang et al.
Osteoarthritis (OA) and rheumatoid arthritis (RA) are highly prevalent joint diseases globally. The common pathological features include synovial inflammation, swelling, joint destruction, and bone remodeling. Arthritis development is assoc...
Association Between Gut Microbiota and Pneumonia Risk: A Systematic Review and Mendelian Randomization [0.03%]
肠道菌群与肺炎风险的相关性：系统评价和孟德尔随机化分析
Qingping Deng,Yuanyuan Liu,Hui Rong et al.
Qingping Deng et al.
Background: The gut-lung axis represents a critical pathway potentially modulating COVID-19 pathogenesis. We employed meta-analysis to investigate the Mendelian randomization (MR) studies for the putative causal relationships between gut mi...
Total Bile Acids: A Game-Changer in Predicting Short-Term Outcomes in AIS Patients Undergoing Thrombolysis [0.03%]
总胆酸测定在急性缺血性卒中溶栓患者短期预后评估中的应用价值
Zhuohang Liu,Min Chu,Zengyu Zhang et al.
Zhuohang Liu et al.
Introduction: Total bile acids (TBAs) are emerging as potential prognostic biomarkers in acute ischemic stroke (AIS). This study aimed to evaluate the association between TBA levels and long-term outcomes in AIS patients receiving intraveno...
Extracellular Matrix Stiffness Enhancement Promotes Docetaxel Resistance in Prostate Cancer via Inhibition of Apoptosis Mediated by Upregulation of PRRX1 [0.03%]
外基质刚度增强通过PRRX1上调介导的凋亡抑制促进前列腺癌多西他赛耐药性
Jiahao Chen,Mengting Chen,Zhiwen Xie et al.
Jiahao Chen et al.
Background: Prostate cancer (PCa) poses a significant health burden for men, with docetaxel constituting the primary therapeutic option for patients with metastatic PCa. However, the mechanisms governing docetaxel resistance remain incomple...
NDUFS1 upregulates ENaCα by NAD+ to promote alveolar fluid clearance in acute lung injury [0.03%]
NDUFS1通过NAD+上调ENaCα以促进急性肺损伤的肺泡液清除功能
Mengmeng Wang,Mengting Chen,Jianping Zhu et al.
Mengmeng Wang et al.
Alveolar edema and following respiratory distress results in the aggravation of epithelial damage and the progression of acute lung injury (ALI), however, with unclear molecular mechanism remained to be elucidated. Through proteomic screeni...
Effect of Pituitary-Target Gland Axis on RAAS in the Context of COVID-19 [0.03%]
2019冠状病毒病背景下下丘脑-靶腺轴对RAAS的影响
Baofeng Wu,Ru Li,Qinhao Liu et al.
Baofeng Wu et al.
The pituitary gland is a very important endocrine gland in the human body. It secretes and releases many hormones crucial for controlling physiological processes, such as energy metabolism, human growth and development, and reproduction. Th...
Psoriasis Patients are Associated with Increased Risk of New-Onset Irritable Bowel Syndrome: A Multicenter, Retrospective Cohort Study [0.03%]
银屑病患者新发肠易激综合征的风险增加：一项基于多中心回顾性队列研究的证据
Shiu-Jau Chen,Hui-Chin Chang,Shuo-Yan Gau
Shiu-Jau Chen
Background: Psoriasis is a chronic systemic inflammatory disease linked to multiple comorbidities. The association between psoriasis and irritable bowel syndrome (IBS) remains insufficiently characterized. Methods: We conducted a retrospect...
Role of Iron Metabolic Disturbances and Inflammatory Iron Biomarkers in Liver Transplant Prognosis [0.03%]
铁代谢紊乱和炎症铁生物标志物在肝脏移植预后中的作用
Lu Yu,Jun Xu,Ting Que et al.
Lu Yu et al.
Iron metabolism plays a pivotal role in liver transplantation, significantly impacting outcomes for both donors and recipients. The liver, central to iron homeostasis, is often impaired in chronic liver diseases leading to metabolic disorde...