Analysis of the efficacy of autologous peripheral blood stem cell transplantation in high-risk neuroblastoma [0.03%]
自身外周血干细胞移植治疗高危型神经母细胞瘤的疗效分析
Jin Yan,Li Jie,Yang Jiaxing et al.
Jin Yan et al.
Objective: This study aimed to analyze the efficacy of autologous peripheral blood stem cell transplantation for high-risk neuroblastoma in China. Methods: The data of 90 high-risk neuroblastoma patients treated with the CCCG-NB 2015 regime...
Superficial Venous-Associated Inflammation from Direct IV Administration of RRx-001 in Rats [0.03%]
大鼠直接静脉给药RRx-001后的浅表静脉相关炎症反应
Scott Caroen,Bryan Oronsky,Tony Reid et al.
Scott Caroen et al.
RRx-001 is a small molecule NLRP3 inflammasome inhibitor with anti-CD47 and antiangiogenic/vascular normalization properties in a Phase 3 clinical trial that has been designated as a drug-device combination by the FDA. In the Phase 1 first-...
EGF Contributes to Hypertrophy of Human Ligamentum Flavum via the TGF-β1/Smad3 Signaling Pathway [0.03%]
表皮生长因子通过转化生长因子-β1/smad3信号通路促进人类黄韧带增生肥厚
Kaifan Yang,Yanlin Chen,Xin Xiang et al.
Kaifan Yang et al.
Background: The most common spinal disorder in elderly is lumbar spinal canal stenosis (LSCS). Previous studies showed that ligamentum flavum hypertrophy (LFH) with fibrosis as the main pathological change is one of the pathogenic factors l...
Protective effect of microorganism biotransformation-produced resveratrol on the high fat diet-induced hyperlipidemia, hepatic steatosis and synaptic impairment in hamsters [0.03%]
微生物转化生成的白藜芦醇对高脂饮食诱导的大鼠血脂异常、脂肪肝及突触损伤的改善作用研究
Chun-Hung Su,Ho-Lin Wang,Min-Ling Tsai et al.
Chun-Hung Su et al.
Background: Resveratrol, a natural antioxidant polyphenol, has the functions of anti-inflammation, anti-cancer, liver protection and cardioprotection. Microorganism biotransformation-produced resveratrol (MBR) product shows higher purity th...
Ivermectin induces cell cycle arrest and caspase-dependent apoptosis in human urothelial carcinoma cells [0.03%]
伊维菌素可诱导人类尿路上皮癌细胞周期阻滞和半胱天冬酶依赖性凋亡
Chun-Liang Tung,Wen-Ying Chao,Yi-Zhen Li et al.
Chun-Liang Tung et al.
Bladder carcinoma is one of the most common malignancies worldwide, and >90% of all bladder cancers are classified as urothelial carcinomas (UC). Surgery, radiotherapy, chemotherapy, targeted therapy, and immunotherapy are evidence-based tr...
Clustering of Chromatin Remodeling Enzymes Predicts Prognosis and Clinical Benefit of Therapeutic Strategy in Pancreatic Cancer [0.03%]
染色质重塑酶的聚类预测了胰腺癌的预后和治疗策略的临床受益性
Hui-Ching Wang,Hsiang-Yao Shih,Chun-Chieh Wu et al.
Hui-Ching Wang et al.
In recent years, translational research and pharmacological targeting of epigenetic modifications have become the focus of personalized therapy for patients with pancreatic cancer. Preclinical and clinical trials targeting post-translationa...
Association of left ventricular global area strain derived from resting 3D speckle-tracking echocardiography and exercise capacity in individuals undergoing treadmill exercise test [0.03%]
基于休息状态三维斑点追踪超声心动图的左心室整体面积应变与受试者踏车运动能力的关系
Tsang-Wei Chang,Han-Chung Hsu,Wei-Chuan Tsai
Tsang-Wei Chang
Background: Left ventricular (LV) global area strain (GAS) is a novel index derived from resting 3D speckle-tracking echocardiography (STE), and its clinical significance has rarely been studied. We examined the association of LV GAS and ex...
Luteolin Reduces Aqueous Extract PM2.5-induced Metastatic Activity in H460 Lung Cancer Cells [0.03%]
黄酮类化合物山柰酚抑制PM2.5诱导的肺癌细胞转移能力
Hui-Wen Lin,Ting-Jing Shen,Nae-Cherng Yang et al.
Hui-Wen Lin et al.
Fine particulate matter (PM2.5) is the critical cause of lung cancer and can further promote tumor cell migration and invasion. This study investigated the effects of luteolin, an antiangiogenic flavonoid agent, on blocking aqueous extract ...
The imaging quantification of multiple organs by dynamic 18F-FDG PET/CT in discharged COVID-19 patients: A prospective pilot study [0.03%]
出院COVID-19患者的动态18F-FDG PET/CT多器官影像定量研究：一项前瞻性初步研究
Jijin Yao,Jing Liu,Lei Bi et al.
Jijin Yao et al.
Purpose: To early identify abnormal lesions by applying the 18F-FDG PET dynamic modeling approach for discharged patients recovering from COVID-19. Methods: Seven discharged COVID-19 patients (COVID-19 group), twelve healthy volunteers (con...
Mulberry polyphenols ameliorate atherogenic migration and proliferation by degradation of K-Ras and downregulation of its signals in vascular smooth muscle cell [0.03%]
桑多酚通过降解K-ras及其信号通路改善血管平滑肌细胞迁移和增殖阻止动脉粥样硬化形成
Ching-Pei Chen,Yi-Liang Wu,Kuei-Chuan Chan et al.
Ching-Pei Chen et al.
Extra-proliferation and increased migration of vascular smooth cells con-tribute to the formation of atherosclerosis. Ras small G proteins play a critical role in the prolif-eration and migration of a wide range of cells. Mulberry, an econo...