CircRNAs in hepatocellular carcinoma: characteristic, functions and clinical significance [0.03%]
肝细胞癌中的环形RNA：特征、功能和临床意义
Yujun Zhou,Xingkang Mao,Rui Peng et al.
Yujun Zhou et al.
Hepatocellular carcinoma (HCC) is one of the most common and serious types of cancer worldwide, with high incidence and mortality rates. Circular RNAs (circRNAs) are a novel class of non-coding RNA with important biological functions. In re...
Can CD147 work as a therapeutic target for tumors through COVID-19 infection? [0.03%]
CD147能否通过COVID-19感染成为肿瘤的治疗靶点？
Hao-Lin Ren,Gui-Min Wen,Zhen-Ying Zhao et al.
Hao-Lin Ren et al.
In this review, we discussed an interesting case infected with "COVID-19" (Corona Virus Disease 2019). The patients with Hodgkin's lymphoma recovered after infection with COVID-19. It may be that COVID-19 activates the patient's immune syst...
Juanjuan Luo,Muhammad Junaid,Naima Hamid et al.
Juanjuan Luo et al.
Glioma, a kind of central nervous system (CNS) tumor, is hard to cure and accounts for 32% of all CNS tumors. Establishing a stable glioma model is critically important to investigate the underlying molecular mechanisms involved in tumorige...
Fish Oil and Selenium with Doxorubicin Modulates Expression of Fatty Acid Receptors and Selenoproteins, and Targets Multiple Anti-Cancer Signaling in Triple-negative Breast Cancer Tumors [0.03%]
鱼油和硒与多柔比星联用调节脂肪酸受体和硒蛋白的表达，并靶向三阴性乳腺癌肿瘤中的多种抗癌信号
Chih-Hung Guo,Min-Yi Shih,Chieh-Han Chung et al.
Chih-Hung Guo et al.
Omega-3 fatty acids from fish oil (FO) and selenium (Se) potentiate some conventional therapies and have anticancer immune potential. This study aims to determine whether FO/Se modulates G-protein-coupled polyunsaturated fatty acid receptor...
Association between serum sphingolipids and necroinflammation of liver tissue pathology in chronic hepatitis B [0.03%]
血清神经节苷脂与慢性乙型肝炎肝组织病理坏死炎症的相关性研究
Yan Ren,Jing Zhao,Manman Xu et al.
Yan Ren et al.
Background & Aims: Accurately identifying liver necroinflammation was essential for the timely implementation of antiviral therapy in chronic hepatitis B(CHB) patients. The sphingolipids were involved in various chronic inflammatory process...
A Bioinformatics Perspective on the Dysregulation of Ferroptosis and Ferroptosis-related Immune Cell Infiltration in Alzheimer's Disease [0.03%]
从生物信息学角度分析铁死亡及其相关免疫细胞浸润在阿尔茨海默病中调节失常的问题
Lusi Zhang,Jia Fang,Zhenchu Tang et al.
Lusi Zhang et al.
Alzheimer's disease (AD) is the most prevalent dementia worldwide, but its pathophysiology and molecular events remain unknown. Herein, we first analyzed the differential expression pattern of patients' AD hippocampus through gene expressio...
Cedrol restricts the growth of colorectal cancer in vitro and in vivo by inducing cell cycle arrest and caspase-dependent apoptotic cell death [0.03%]
cedrol通过诱导细胞周期阻滞和caspase依赖性凋亡细胞死亡来限制体内外结直肠癌的生长
Ju-Huei Chien,Kai-Fu Chang,Shan-Chih Lee et al.
Ju-Huei Chien et al.
Background: Cedrol is a natural sesquiterpene alcohol found in Cedrus atlantica, which has been proven to have a broad spectrum of biological activities, such as antimicrobial, anti-inflammatory, analgesic, anxiolytic, and anti-cancer effec...
A study of the therapeutic mechanism of Jakyakgamcho-Tang about functional dyspepsia through network pharmacology research [0.03%]
基于网络药理学研究嘉 Yakgamcho 汤治疗功能性消化不良的机制
Woo-Gyun Choi,Na Ri Choi,Eun-Jung Park et al.
Woo-Gyun Choi et al.
Herbal medicines have traditionally been used as an effective digestive medicine. However, compared to the effectiveness of Herbal medicines, the treatment mechanism has not been fully identified. To solve this problem, a system-level treat...
DPA promotes hBMSCs osteogenic differentiation by miR-9-5p/ERK/ALP signaling pathway [0.03%]
DPA通过miR-9-5p/ERK/ALP信号通路促进hBMSCs成骨分化
Xiang Gao,Guanhao Hong,Weiqiang Zhan et al.
Xiang Gao et al.
Docosahexaenoic acid (DHA) has been reported potentiate osteogenic differentiation, while Docosapentaenoic acid (DPA), another Omega-3 fatty acid, its contribution to the osteogenic differentiation of human bone-marrow-derived mesenchymal s...
Hongjiang Zhao,Yuan Xu,Hongkai Shang
Hongjiang Zhao
Ferroptosis is a novel kind of regulated cell death distinct from autophagy, apoptosis, and necrosis; it is predominantly caused by the iron-dependent lipid peroxidation. According to studies, numerous conventional signaling pathways and bi...