LncRNA RPPH1 acts as a molecular sponge for miR-122 to regulate Wnt1/β-catenin signaling in hepatocellular carcinoma [0.03%]
长链非编码RNA RPPH1作为分子海绵作用于miR-122以调控肝细胞癌中的Wnt1/β-catenin信号通路
Jian Zhou,Kun Shi,Weifeng Huang et al.
Jian Zhou et al.
This study aimed to explore the role of lncRNA RPPH1 in hepatocellular carcinoma. The expression of RPPH1 and miR-122 was determined by Real-time PCR. Cell proliferation and colony formation assays were employed to monitor cell growth in vi...
Upregulation of Brain's Calcium Binding Proteins in Mitragynine Dependence: A Potential Cellular Mechanism to Addiction [0.03%]
麻藤碱依赖上调大脑钙结合蛋白：潜在的成瘾细胞机制
Murtadha Basheer,Zurina Hassan,Lay-Harn Gam
Murtadha Basheer
Background: Mitragyna speciosa Korth or Kratom is widely used traditionally for its medicinal values. The major alkaloid content of kratom leaves is mitragynine, which binds to opioid receptors to give opioid-like effects. This study aimed ...
Effects of Long-Term Wear and Discontinuation of Orthokeratology Lenses on the Eyeball Parameters in Children with Myopia [0.03%]
长期配戴和间歇停戴OK镜对近视儿童眼轴参数的影响
Qin Zhu,Jie Yin,Xuejiao Li et al.
Qin Zhu et al.
Objective: To evaluate the effects of long-term wear and discontinuation of the orthokeratology lenses (Orth-K) on the biological parameters of eyeballs in children with myopia. Methods: In this prospective study, a total of 308 subjects wi...
Randomized Controlled Trial
International journal of medical sciences. 2023 Jan 1;20(1):50-56. DOI:10.7150/ijms.79496 2023
Glutamine synthetase regulates the immune microenvironment and cancer development through the inflammatory pathway [0.03%]
谷氨酰胺合成酶通过炎症通路调控免疫微环境和癌症的发展
Do Thi Minh Xuan,Chung-Che Wu,Wei-Jan Wang et al.
Do Thi Minh Xuan et al.
Although adjuvant tamoxifen therapy is beneficial to estrogen receptor-positive (ER+) breast cancer patients, a significant number of patients still develop metastasis or undergo recurrence. Therefore, identifying novel diagnostic and progn...
Characterization of SARS-CoV-2 recombinants and emerging Omicron sublineages [0.03%]
SARS-CoV-2 重组体和新兴奥密克戎亚谱系的特征分析
Yuliang Wang,Yiyin Long,Feng Wang et al.
Yuliang Wang et al.
The SARS-CoV-2 Omicron is currently the predominant circulating variant in the COVID-19 pandemic. The dominating Omicron sublineages respond to host immune pressure and develop advantageous mutations or genetic recombination, which result i...
Prognostic and Immune Infiltration Value of Proteasome Assembly Chaperone (PSMG) Family Genes in Lung Adenocarcinoma [0.03%]
蛋白酶体组装伴侣(PSMG)家族基因在肺腺癌中的预后和免疫浸润价值
Do Thi Minh Xuan,I-Jeng Yeh,Che-Yu Su et al.
Do Thi Minh Xuan et al.
The complexity of lung adenocarcinoma (LUAD) including many interacting biological processes makes it difficult to find therapeutic biomarkers for treatment. Previous studies demonstrated that PSMG (proteasome assembly chaperone) family mem...
A Review of the Impact of Pharmacogenetics and Metabolomics on the Efficacy of Metformin in Type 2 Diabetes [0.03%]
药理遗传学和代谢组学对二型糖尿病患者二甲双胍疗效影响的综述
Zoheir A Damanhouri,Huda M Alkreathy,Fawaz A Alharbi et al.
Zoheir A Damanhouri et al.
Metformin is the most often prescribed drug for people with type 2 diabetes (T2D). More than 120 million patients with T2D use metformin worldwide. However, monotherapy fails to achieve glycemic control in a third of the treated patients. G...
Post-Intensive Care Unit Multidisciplinary Approach in Patients with Severe Bilateral SARS-CoV-2 Pneumonia [0.03%]
严重双侧SARS-CoV-2肺炎患者在重症监护病房后多学科综合治疗方案
Ana María Sánchez-García,Pilar Martínez-López,Adela María Gómez-González et al.
Ana María Sánchez-García et al.
Background: Short and long-term sequelae after admission to the intensive care unit (ICU) for coronavirus disease 2019 (COVID-19) are to be expected, which makes multidisciplinary care key in the support of physical and cognitive recovery. ...
Meibomian gland dysfunction patients benefit in ocular parameters and tear chemokines after thermal pulsation treatment [0.03%]
热脉动治疗对睑板腺功能障碍患者的眼部参数和泪液趋化因子的影响
Wenting Liu,Tong Lin,Lan Gong
Wenting Liu
Objectives: To investigate the effect of thermal pulsation treatment on meibomian gland function, ocular parameters and tear inflammatory cytokines compared with the warm compress group. Methods: Twenty-five participants with MGD underwent ...
Inflammation as an exacerbation marker and target for prophylaxis against Coronavirus Disease 2019-related thrombosis [0.03%]
炎症作为新型冠状病毒2019相关血栓形成加重标志物及预防靶点
Daisuke Ono,Yuko Ohno,Yoshihiko Izumida et al.
Daisuke Ono et al.
Objectives: There are currently no appropriate markers and target for prophylaxis against COVID-19-related thrombosis, especially in the not-severe cases. We tested the hypothesis that inflammation is a suitable marker and target for prophy...