Cardiovascular and lipid-lowering effects of a marine lipoprotein extract in a high-fat diet-induced obesity mouse model [0.03%]
一种海洋脂蛋白提取物对高脂饮食诱导的肥胖型小鼠的心血管和降血脂作用研究
Iván Carrera,Lola Corzo,Vinogran Naidoo et al.
Iván Carrera et al.
Obesity is a major health challenge worldwide, with implications for diabetes, hypertension and cardiovascular disease (CVD). Regular consumption of dark-meat fish is linked to a lower incidence of CVD and associated metabolic disorders due...
S100A11 Promotes Metastasis via AKT and ERK Signaling Pathways and Has a Diagnostic Role in Hepatocellular Carcinoma [0.03%]
S100A11通过AKT和ERK信号通路促进肝细胞癌转移并具有诊断价值
Mei Zheng,Huan Meng,Yunhui Li et al.
Mei Zheng et al.
Hepatocellular carcinoma (HCC) is the most common and malignant liver tumor worldwide, although the treatment approaches for HCC continue to evolve, metastasis is the main reason for high mortality rates. S100 calcium-binding protein A11 (S...
Genomic Fingerprint Associated with Familial Idiopathic Pulmonary Fibrosis: A Review [0.03%]
与家族特发性肺纤维化相关的基因组特征：综述文章
Dongyan Ding,Rong Gao,Qianfei Xue et al.
Dongyan Ding et al.
Idiopathic pulmonary fibrosis (IPF) is a severe interstitial lung disease; although the recent introduction of two anti-fibrosis drugs, pirfenidone and Nidanib, have resulted in a significant reduction in lung function decline, IPF is still...
Denervation Atrophy of Skeletal Muscle is Not Influenced by Numb Levels in Mice [0.03%]
小鼠骨骼肌脱神经萎缩不受numb水平的影响
Abdurrahman Aslan,Lauren Harlow,Xin-Hua Liu et al.
Abdurrahman Aslan et al.
Skeletal muscle undergoes rapid and extensive atrophy following nerve transection though the underlying mechanisms remain incompletely understood. We previously showed transiently elevated Notch 1 signaling in denervated skeletal muscle tha...
Multiclassifier Radiomics Analysis of Ultrasound for Prediction of Extrathyroidal Extension in Papillary Thyroid Carcinoma in Children [0.03%]
儿童乳头状甲状腺癌超声多分类器影像组学分析预测肿瘤外侵性
Jie Li,Fantong Xia,Xiaoqing Wang et al.
Jie Li et al.
Objective: To explore extrathyroidal extension (ETE) in children and adolescents with papillary thyroid carcinoma using a multiclassifier ultrasound radiomic model. Methods: In this study, data from 164 pediatric patients with papillary thy...
Randomized Controlled Trial
International journal of medical sciences. 2023 Jan 22;20(2):278-286. DOI:10.7150/ijms.79758 2023
m6A modifications of circular RNAs in ischemia-induced retinal neovascularization [0.03%]
缺血诱导视网膜新生血管化过程中circRNA的m6A修饰变化规律研究
Yedi Zhou,Bingyan Li,Zicong Wang et al.
Yedi Zhou et al.
Ischemia-induced pathological neovascularization in the retina is a leading cause of blindness in various age groups. The purpose of the current study was to identify the involvement of circular RNAs (circRNAs) methylated by N6-methyladenos...
Aberrant alteration of peripheral B lymphocyte subsets in hepatocellular carcinoma patients [0.03%]
肝细胞癌患者外周B淋巴细胞亚群的异常改变
Jiaoxiang Wu,Yue Wang,Shihao Bai et al.
Jiaoxiang Wu et al.
Although B lymphocytes are widely known to participate in the immune response, the conclusive roles of B lymphocyte subsets in the antitumor immune response have not yet been determined. Single-cell data from GEO datasets were first analyze...
Natural Killer Cell Activity Test Helps to Suspect Aggressive Natural Killer Cell Leukemia - Diagnostic Challenge [0.03%]
自然杀伤细胞活性试验有助怀疑是侵袭性自然杀伤细胞白血病-诊断挑战
Eunkyoung You,Chan-Jeoung Park,Min Young Lee et al.
Eunkyoung You et al.
Aggressive natural killer cell leukemia (ANKL) is a rare disease with an aggressive clinical course. We aimed to assess the clinicopathological characteristics of the difficult to diagnose ANKL. During ten years, nine patients with ANKL wer...
6-shogaol is a potential treatment for Head and Neck Squamous Cell Carcinoma [0.03%]
6-姜酚可能是治疗头颈鳞状细胞瘤的药物
Cheng-Ming Hsu,Hui-Chen Su,Ming-Yu Yang et al.
Cheng-Ming Hsu et al.
Objective: Natural products in diet have shown a potential role in the prevention and treatment of cancer. Ginger (Zingiber officinale Roscoe) is a great candidate because of its properties of anti-inflammatory, antioxidant, and anti-cancer...
Klotho promotes AMPK activity and maintains renal vascular integrity by regulating the YAP signaling pathway [0.03%]
克洛托通过调节YAP信号通路促进AMPK活性并维持肾血管完整性
Lei Luo,Jianming Guo,Yi Li et al.
Lei Luo et al.
The development and formation of mammalian blood vessels are closely related to the regulation of signal transduction pathways. Klotho/AMPK and YAP/TAZ signaling pathways are closely related to angiogenesis, but the internal relationship be...