IL-27 deficiency inhibits proliferation and invasion of trophoblasts via the SFRP2/Wnt/β-catenin pathway in fetal growth restriction [0.03%]
缺IL-27通过SFRP2/Wnt/β-catenin信号途径抑制胎盘绒毛膜侵袭和增殖在胎儿生长受限中的作用
Xin-Yan Zhang,Xue-Yun Qin,Hui-Hui Shen et al.
Xin-Yan Zhang et al.
Background: Fetal growth restriction (FGR) is characterized by restricted fetal growth and dysregulated placental development. The etiology and pathogenesis still remain elusive. IL-27 shows multiple roles in regulating various biological p...
Qinggan Huoxue Recipe attenuates Alcoholic Liver Disease by suppressing PI3K/AKT signaling pathway based on network pharmacology [0.03%]
基于网络药理学的青肝活血方通过抑制PI3K/AKT信号通路治疗酒精性肝病
Junmin Wang,Yifei Lu,Caiyun Zhang et al.
Junmin Wang et al.
Qinggan Huoxue Recipe (QGHXR) is originated from Xiao Chaihu Decotion. Many experimental studies have confirmed that QGHXR can significantly alleviate the symptoms of alcoholic liver disease (ALD), but the detailed mechanism is still unclea...
Robot-assisted versus conventional laparoscopic radical hysterectomy in cervical cancer stage IB1 [0.03%]
机器人辅助与传统腹腔镜广泛子宫切除术在IB1期宫颈癌中的应用
Sang Il Kim,Ji Geun Yoo,Sung Jong Lee et al.
Sang Il Kim et al.
Objective: The aim of this study was to compare survival outcomes of robot-assisted laparoscopic radical hysterectomy (RRH) and conventional laparoscopic radical hysterectomy (LRH) in cervical cancer stage IB1. Method: This is a retrospecti...
Exogenous Lipoxin A4 attenuates IL4-induced Mucin Expression in Human Airway Epithelial Cells [0.03%]
外源性白三烯脂氧素A4能减弱人呼吸道上皮细胞中IL4致黏蛋白表达作用
Eun-Hye Seo,Seung Hyun Lee,Bo Yoon Choi et al.
Eun-Hye Seo et al.
Introduction: The proinflammatory cytokine interleukin-4 (IL-4) induces mucus hypersecretion by human airway epithelial cells and the MAP kinase signalling pathway may be important in terms of IL-4-induced MUC5AC gene expression. Lipoxin A4...
Nicotinamide mononucleotides alleviated neurological impairment via anti-neuroinflammation in traumatic brain injury [0.03%]
烟酸单核苷酸通过抗神经炎症缓解创伤性脑损伤引起的神经功能缺损
Xiaolu Zhu,Jin Cheng,Jiangtao Yu et al.
Xiaolu Zhu et al.
Traumatic brain injury (TBI) is one of the main factors of death and disability in adults with a high incidence worldwide. Nervous system injury, as the most common and serious secondary injury after TBI, determines the prognosis of TBI pat...
Bioinformatics-based analysis of the roles of sex hormone receptors in endometriosis development [0.03%]
基于生物信息学的性激素受体在子宫内膜异位症发生发展中作用的分析研究
Xiaoling Zhao,Weimin Kong,Chunxiao Zhou et al.
Xiaoling Zhao et al.
Endometriosis is a hormone-dependent disease in women of reproductive age and seriously affects women's health. To analyze the involvement of sex hormone receptors in endometriosis development, we performed bioinformatics analysis using fou...
Videofluoroscopy dysphagia severity scale is predictive of subsequent remote pneumonia in dysphagia patients [0.03%]
吞咽困难患者 videofluoroscopic 吞咽障碍严重程度量表能够预测后续的远处肺炎
Poyin Huang,Yi-Chiung Hsu,Chien-Hsun Li et al.
Poyin Huang et al.
Introduction: Dysphagia-associated pneumonia is a critical health issue especially in the elders and stroke patients which carries a poorer prognosis. Therefore, we aim to identify methods with the potentials to predict subsequent pneumonia...
Significant impact of body mass index on the relationship between increased white blood cell count and new-onset diabetes [0.03%]
体重指数对血常规中性粒细胞升高与新发糖尿病关系的修饰作用分析
Chieh-Yu Hsieh,Wen-Hsien Lee,Yi-Hsueh Liu et al.
Chieh-Yu Hsieh et al.
An elevated white blood cell (WBC) count has been linked to incident diabetes. WBC count has been positively associated with body mass index (BMI), and elevated BMI has been reported to be a strong predictor of future diabetes. Hence, the a...
Wei Yong,Jiajia Wang,Yan Leng et al.
Wei Yong et al.
Contemporary scientists need no "p value" and "relative risk" statistics to be exquisitely aware of the increasing prevalence of obesity and complications posed by obesity. It is now well recognized that obesity is strongly associated with ...
Yun Feng,Yaping Liu,Qian Zhao et al.
Yun Feng et al.
Objectives: The objective of this study is to explore the incidence, characteristics, risk factors, and prognosis of liver injury in patients with COVID-19. Methods: We collected clinical data of 384 cases of COVID-19 and retrospectively an...