Ahmed Jasim Mahmood Al-Mashhadani,Qi Gong,Franko Shehaj et al.
Ahmed Jasim Mahmood Al-Mashhadani et al.
Background: Rat models are widely used to study cataracts due to their cost-effectiveness and prominent physiological and genetic similarities to humans The objective of this study was to identify genes involved in cataractogenesis due to g...
Nutraceutical Evaluation of Trigonelline's Therapeutic Potential by Targeting Bladder Cancer Stem Cells and Cancer-Associated Fibroblasts via Downregulation of TGFβ3/GLI2/YAP1 Signaling Hub [0.03%]
通过下调TGFβ3/GLI2/YAP1信号中心针对膀胱癌症干细胞和癌相关成纤维细胞从而评估曲古罗宁的治疗潜力
Chien-Chang Kao,Jing-Wen Shih,Huong Thi Luu Kim Huynh et al.
Chien-Chang Kao et al.
Trigonelline (TGN), an alkaloid identified in medicinal plants such as coffee (Coffea spp.) and fenugreek (Trigonella foenum-graecum), has demonstrated significant anticancer properties across various malignancies, yet its efficacy in bladd...
Exploring the Plasma Proteome: Identifying Hub Proteins linking Aging, Homeostasis, and Organ Function [0.03%]
探索血浆蛋白质组：识别与衰老、稳态和器官功能相关的中心蛋白质
Juan Jiao,Fei Gao,Hongye Zhao et al.
Juan Jiao et al.
As effectors of interactions between genes and the environment, plasma proteins can monitor homeostasis and reflect the aging state of an organism. However, biomarkers of aging that are associated with homeostasis are still unclear. This st...
Serum legumain is a potential biomarker for community-acquired pneumonia: a prospective cohort study [0.03%]
血清legumain是社区获得性肺炎的潜在生物标志物：一项前瞻性队列研究
Xian-Ling Meng,Kai-Shu Ma,Kai-Xin Qu et al.
Xian-Ling Meng et al.
Background: Legumain is a cysteine endopeptidase that belongs to the C13 family. Many studies have revealed that legumain plays a vital pathogenic role in various respiratory diseases. The aim of this study was to explore the role of leguma...
Therapeutic Drug Monitoring for Lacosamide in Chinese Pediatric Patients with Epilepsy: Focus on Clinical Effectiveness, Tolerability and Drug Interactions [0.03%]
拉考沙胺在癫痫患儿中的治疗药物监测：重点关注临床疗效、耐受性和药物相互作用
Fengqian Mao,Shunan Chen,Yani Hu et al.
Fengqian Mao et al.
Objective: To investigate the effectiveness and tolerability of lacosamide (LCM) and to select a better reference range for its concentration in plasma for Chinese pediatric patients with epilepsy. In addition, it is necessary to evaluate t...
Comparative Efficacy of Silicone Sheets and Hyperbaric Oxygen Therapy in Post-Surgical Scar Prevention: A Prospective Observational Study [0.03%]
硅胶片与高压氧疗法在术后疤痕预防中的比较疗效：一项前瞻性观察研究
Po-Chung Chen,Tzung-Cheng Liao,Chang-Yi Chou et al.
Po-Chung Chen et al.
Background: Postoperative scarring can significantly impact physical function, aesthetic outcomes, and overall quality of life. Effective scar management is crucial to mitigate these effects. This study aimed to compare the efficacy of sili...
Randomized Controlled Trial
International journal of medical sciences. 2025 Feb 11;22(5):1167-1175. DOI:10.7150/ijms.108397 2025
Prognostic Value of Circulating Lymphocyte Subsets in Cervical Cancer Following Postoperative Radiotherapy [0.03%]
术后放疗宫颈癌患者循环淋巴细胞亚群的预后价值
Shanshan Wang,Mengli Zhao,Zhongrong Gao et al.
Shanshan Wang et al.
Background and objective: The prognostic value of circulating lymphocyte subsets in cervical cancer patients receiving postoperative radiotherapy remains unclear. This study aimed to explore the prognostic significance of these lymphocyte s...
A synthetic molecule targeting STAT3 against human oral squamous cell carcinoma cells [0.03%]
靶向STAT3对抗人口腔鳞状细胞癌细胞的合成分子
Li-Yuan Bai,Eman M E Dokla,Po-Chen Chu et al.
Li-Yuan Bai et al.
Oral squamous cell carcinoma (OSCC), one of the most common cancers in Taiwan, needs new therapeutic agents and treatments. The aim of this study was to investigate the anti-proliferative activity of {N-[3-chloro-4-[5-[3-[[[4-[(cyclopropylc...
Lung commensal bacteria promote lung cancer progression through NK cell-mediated immunosuppressive microenvironment [0.03%]
肺共生菌通过NK细胞介导的免疫抑制微环境促进肺癌进展
Haiyang Wang,Jiayi Hu,Yirou Ma et al.
Haiyang Wang et al.
Symbiotic microbiota pervades the majority of the human body's organs and tissues, functioning as crucial regulators of both health maintenance and disease progression. Pertinently, lung adenocarcinoma has been indisputably linked to chroni...
Research Progress on Contrast-Enhanced Ultrasound (CEUS) Assisted Diagnosis and Treatment in Liver-Related Diseases [0.03%]
对比增强超声在肝脏相关疾病诊疗中的研究进展
Xiaoqing Ying,Shangxin Dong,Yuanyuan Zhao et al.
Xiaoqing Ying et al.
Liver-related diseases, such as hepatocellular carcinoma (HCC) and cirrhosis, are globally prevalent and significantly contribute to mortality rates. Despite the availability of various imaging techniques for liver evaluation, a consensus r...