The Role of Mesenchymal Stem Cells in Treating Diabetic Kidney Disease: Immunomodulatory Effects and Kidney Regeneration [0.03%]
间充质干细胞在治疗糖尿病肾病中的作用：免疫调节和肾脏再生
Po-Jen Hsiao,Wen-Yi Kao,Li-Chin Sung et al.
Po-Jen Hsiao et al.
Background: Diabetic kidney disease (DKD), also known as diabetic nephropathy (DN), is characterized by progressive glomerulosclerosis and chronic inflammation. The potential of mesenchymal stem cells (MSCs) in treating DKD could be explore...
Jia-Lin Wang,Lan-Ting Wu,Yan-Ling Wang
Jia-Lin Wang
Background: Premature acute coronary syndrome (ACS) has attracted attention due to high rates of recurrent ischemic events and mortality. We aimed to explore the characteristic changes of the ocular hemodynamics in patients with premature A...
Targeted inhibition of integrin αVβ3 induces cytotoxicity and suppresses migration ability in ovarian cancer cells and tumor spheroids [0.03%]
整合素αVβ3的靶向抑制诱导卵巢癌细胞及肿瘤细胞团的毒性并抑制其迁移能力
I-Lun Hsin,Ling-Yen Chiu,Jiunn-Liang Ko et al.
I-Lun Hsin et al.
Ovarian cancer is a gynecological malignancy that has poor prognosis and high lethality. Integrin αVβ3 is highly expressed in solid cancer cells, including ovarian cancer, and is important in proliferation and cell migration. In this stud...
Erratum: Interaction of RAS Activation and Lipid Disorders Accelerates the Progression of Glomerulosclerosis: Erratum [0.03%]
交互作用的RAS激活和脂质障碍加速了肾小球硬化的进展：勘误表
Kun-Ling Ma,Jie Ni,Chang-Xian Wang et al.
Kun-Ling Ma et al.
[This corrects the article DOI: 10.7150/ijms.6635.]. © The author(s).
The Value of Texture Analysis of Multi-parameter MRI Images in Distinguishing Benign and Malignant Lesions of O-RADS MRI 4 Lesions [0.03%]
多参数MRI图像纹理分析在O-RADS MRI 4病变良恶性鉴别中的价值
Yan Lei,Hanzhou Tang,Lianlian Liu et al.
Yan Lei et al.
Objectives: To investigate the diagnostic performance of texture analysis using multi-parameter MRI in distinguishing between benign and malignant lesions with ovarian-adnexal magnetic resonance imaging report and data system (O-RADS MRI) s...
Comprehensive Multi-Omics Analysis Identifies FUT1 as a Prognostic and Therapeutic Biomarker Across Pan-Cancer [0.03%]
综合多组学分析鉴定FUT1为跨癌症的预后和治疗生物标志物
Yunqing Liu,Guanjun Chen,Xiaotian Yuan et al.
Yunqing Liu et al.
Fucosyltransferase 1 encodes a Golgi membrane protein involved in H-antigen precursor production and plays a critical role in tumor-associated glycosylation and angiogenesis. While FUT1 is known to enhance tumor stemness, adhesion, migratio...
LncRNA FTX accelerates the progression of hepatocellular carcinoma by FTX/miR-374a-3p/HMGB1 pathway [0.03%]
长链非编码RNA FTX通过 FTX/miR-374a-3p/HMGB1通路促进肝细胞癌进展
Min Zhang,Songman Yu,Shang Gao et al.
Min Zhang et al.
The situation regarding Hepatocellular carcinoma (HCC) is severe, with high incidence and mortality rates worldwide. Abnormal expression of long noncoding RNAs (LncRNAs) has been implicated in the progression of malignant tumors. Although t...
Low-dose Spironolactone Combined with ACEIs/ARBs May Reduce Cardiovascular Events in Patients with CKD Stages 3b-5: A Nationwide Population-Based Cohort Study in Taiwan [0.03%]
台湾全国性队列研究：低剂量螺内酯联合ACEI/ARBs可能减少CKD分期3b-5患者的心血管事件
Li-Nien Chien,Po-Jen Hsiao,Chih-Chien Chiu et al.
Li-Nien Chien et al.
Background: ACE inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) are commonly prescribed for hypertension and chronic kidney disease (CKD) management, but they can increase the risk of renal function deterioration and hyperkalaem...
Multi-omics and single-cell analysis reveals machine learning-based pyrimidine metabolism-related signature in the prognosis of patients with lung adenocarcinoma [0.03%]
多组学和单细胞分析揭示了基于机器学习的与肺癌腺癌患者预后相关的嘧啶代谢标志物
Tong Hu,Run Shi,Yangyue Xu et al.
Tong Hu et al.
Background: Pyrimidine metabolism is a hallmark of tumor metabolic reprogramming, while its significance in the prognostic and therapeutic implications of patients with lung adenocarcinoma (LUAD) still remains unclear. Methods: In this stud...
Transarterial chemoembolization versus hepatic arterial infusion chemotherapy as first treatment for hepatocellular carcinoma with macrovascular invasion [0.03%]
肝细胞癌伴大血管侵犯的初始治疗：经动脉化疗栓塞与肝动脉灌注化疗的对比研究
Benyi He,Min Deng,Shaohua Li et al.
Benyi He et al.
Introduction: Transarterial chemoembolization (TACE) is an optional treatment for hepatocellular carcinoma (HCC) patients with macrovascular invasion (MVI) and without extrahepatic metastasis (EHM). As a recently emerging approach, the effi...