Genetic variant rs2243115 of the IL-12/IL-35 pathway contributes to the risk of coronary artery disease [0.03%]
白细胞介素12/35信号通路遗传变异体rs2243115与冠心病易感性的关联研究
Qianwen Chen,Wenjuan Zhang,Tian Xie et al.
Qianwen Chen et al.
Background: Coronary artery disease (CAD) involves inflammation. IL-12p35, a common subunit of both IL-12 and IL-35, is encoded by the IL12A gene and is a potential therapeutic target in CAD. We probed into the genetic relationships between...
Emodin: an alveolar macrophage protector in acute pancreatitis induced lung injury [0.03%]
大黄素通过保护肺泡巨噬细胞防治急性胰腺炎诱导的ARDS病理损害
Zhe Chen,Xuanchi Dong,Yongwei Song et al.
Zhe Chen et al.
Background: Emodin (EMO), an anthraquinone derivative from roots and leaves of various plants, has been widely used in many inflammatory diseases. Alveolar macrophages (AMs) play a critical role in maintaining alveolar homeostasis in the lu...
Solute Carrier Family 35 A2 (SLC35A2) Promotes Tumor Progression through MYC-Mediated Pathways in Colorectal Cancer [0.03%]
溶质载体家族35成员A2(SLC35A2)通过MYC介导的信号通路促进结直肠癌进展
Kuei-Yen Tsai,Po-Li Wei,Cheng-Chin Lee et al.
Kuei-Yen Tsai et al.
Colorectal cancer (CRC) is one of the most prevalent cancers, posing a significant threat to human life. Although therapeutic approaches for advanced-stage patients have improved in recent years, there is still room for enhancing treatment ...
Oncogenic and Immunological Roles of FRS2 and its Potential Value in Retroperitoneal Liposarcoma: from Bioinformatics Analysis to Clinicopathological Evidence [0.03%]
FRS2的致癌及免疫作用及其在后腹膜脂肪肉瘤中的潜在价值：从生物信息学分析到临床病理证据
Hao Yu,Shuquan Li,Yifan Wu et al.
Hao Yu et al.
Background: Retroperitoneal liposarcoma (RLPS) is a rare malignancy with no effective treatment beyond surgical intervention. Identifying novel therapeutic targets and prognostic markers is critical to improving outcomes. Fibroblast growth ...
Erratum: Overexpression of ATAD2 indicates Poor Prognosis in Oral Squamous Cell Carcinoma: Erratum [0.03%]
ATAD2过度表达表明口腔鳞状细胞癌预后不良：勘误通知书
Xiao-Long Wang,Shuo Wang,Zhi-Zhong Wu et al.
Xiao-Long Wang et al.
[This corrects the article DOI: 10.7150/ijms.46809.]. © The author(s).
Published Erratum
International journal of medical sciences. 2025 Mar 28;22(8):1978. DOI:10.7150/ijms.112159 2025
Hematological parameters and major adverse cardiovascular events: a prospective study in a Chinese population involving 2,970 participants [0.03%]
血细胞参数与主要不良心血管事件：一项涉及2970名中国人的前瞻性研究
Hongna Mu,Xinyue Wang,Xianghui Zhao et al.
Hongna Mu et al.
Hematological parameters are among the most accessible and routinely performed clinical tests. Recent studies have gradually revealed their potential for risk prediction. This study aimed to assess the association between hematological para...
Exploring the Relationship Between Gut Microbiota and Aortic Stenosis: Role of Inflammatory Proteins, Blood Metabolites, and Immune Cells [0.03%]
探究肠道菌群与主动脉瓣狭窄的关系：炎症蛋白、血液代谢物和免疫细胞的作用
Fanhui Jing,Jiapeng Zhou,Fengwen Zhang et al.
Fanhui Jing et al.
Background: Aortic stenosis is the most prevalent valvular heart disease in high-income population, and there are currently no medical therapies to slow the disease progression. Given that gut microbiota influences the immune system, lipid ...
Danqin Lu,Yingying Zhang,Ping Zhu et al.
Danqin Lu et al.
The ubiquitin-proteasome system (UPS) is a major pathway of specific intracellular protein degradation through proteasome degradation of ubiquitin-labeled substrates. Numerous biological processes, including the cell cycle, transcription, t...
Bioprospection of Hura crepitans metabolites against oxidative stress and inflammation: An in vitro and in silico exploration [0.03%]
基于Hura crepitans代谢物的生物勘探对抗氧化应激和炎症的研究：一种体外和分子模拟研究方法
Yu-Cheng Kuo,Bashir Lawal,Halimat Yusuf Lukman et al.
Yu-Cheng Kuo et al.
Background: Despite the recognized therapeutic potential of Hura crepitans, its mechanistic antioxidant and anti-inflammatory actions remain underexplored. Methods: This study investigates the inhibitory effects, binding stability, and inte...
MUC15 acts as a tumor suppressor gene which correlates with prognosis and immune infiltration in esophageal squamous cell carcinoma [0.03%]
MUC15作为食管鳞癌的肿瘤抑制基因并与预后和免疫浸润相关
Xiang Fei,Ai-Li Wang,Hao Wu et al.
Xiang Fei et al.
Esophageal squamous cell carcinoma (ESCC), as a common malignant tumor of the digestive system, has been a challenge in improving and prolonging the postoperative survival of patients. This study aims to identify novel biomarkers that can g...