Targeting SNRPE to Induce Pyroptosis Enhances Antitumor Immunity in Breast Cancer [0.03%]
靶向SNRPE诱导细胞炎性焦亡可增强乳腺肿瘤免疫治疗效果
Zaixiong Ji,Zilin Wang,Xinyu Guo et al.
Zaixiong Ji et al.
Background: Although SNRPE is a core spliceosomal component that guides pre-mRNA splicing in eukaryotic cells, its impact on mammary carcinoma prognosis and the immune microenvironment remains unclear. Pyroptosis, an inflammatory cell death...
Ellagic acid suppresses the human renal carcinoma cell migration and invasion by targeting the RUNX2/MMP1 expression [0.03%]
ellagic酸通过靶向RUNX2/MMP1表达抑制人类肾细胞癌迁移和侵袭
Po-Yu Huang,Tung-Wei Hung,Yi-Hsien Hsieh et al.
Po-Yu Huang et al.
Ellagic acid (EA) exerts anti-carcinogenic activity in various types of cancer. Matrix metalloproteinases (MMPs) are critical mediators in the pathogenesis of renal cell carcinoma (RCC) metastasis. Using in vitro experiments, this study aim...
Associations of the Total Cholesterol/high-density Lipoprotein Cholesterol Ratio with Outcomes in Lupus Nephritis [0.03%]
总胆固醇/高密度脂蛋白胆固醇比率与狼疮性肾炎预后之间的关系
Xiaolei Shi,Yaoyao Tang,Wang Xiang et al.
Xiaolei Shi et al.
Objectives: Dyslipidemia is common in lupus nephritis (LN). However, the relationship between the total cholesterol/high-density lipoprotein cholesterol (TC/HDL-C) ratio and LN remains unclear. This study was designed to investigate the ass...
CEP55 as a prognostic indicator and a predictive marker in oral squamous cell carcinoma [0.03%]
CEP55作为口腔鳞状细胞癌预后指标和预测标记物的研究
Ying Han,Xin Hu,Haofeng Xiong et al.
Ying Han et al.
Objective: To investigate the role of CEP55 in the occurrence and development of oral squamous cell carcinoma (OSCC). Materials and Methods: Through the utilization of the online OSCC database and bioinformatic analysis, we examine CEP55 ex...
Cordycepin ameliorates morphine tolerance by inhibiting spinal cord ferroptosis and inflammation via targeting SIRT1 [0.03%]
虫草素通过靶向SIRT1抑制脊髓铁死亡和炎症从而缓解阿片类药物耐受性
Zheng Li,Jie Liu,Jie Ju et al.
Zheng Li et al.
Morphine tolerance caused by long-term use of morphine is a major medical problem. Neuroinflammation plays an important role in morphine tolerance, and currently no drugs have been found for clinical use to alleviate neuroinflammation durin...
Risks of cardiovascular disease and cerebrovascular disease following kidney transplantation: A nationwide, population-based cohort study [0.03%]
肾脏移植后心血管疾病和脑血管疾病的发病风险：一项基于人群的全国性队列研究
Tung-Han Tsai,Kuang-Hua Huang,Hsin Chen et al.
Tung-Han Tsai et al.
Background: Kidney transplant recipients (KTRs) have an increased risk for cardiovascular disease (CVD) and cerebrovascular disease (CBD). This study investigated the risks of CVD and CBD following kidney transplantation. Materials and meth...
Novel insights into the role of ferroptosis in temporomandibular joint osteoarthritis and knee osteoarthritis [0.03%]
铁死亡在颞下颌关节骨关节炎和膝关节骨关节炎中的作用的新见解
Yuxin Zhang,Dahe Zhang,Xiaoyu Liao et al.
Yuxin Zhang et al.
Osteoarthritis (OA) is a prevalent degenerative joint disease characterized by pain, limited movement, and joint stiffness, significantly impacting the quality of life and imposing substantial economic burdens. This review paper delves into...
Malignant features related PRDX1 associated with osimertinib sensitivity of EGFR-mutant lung adenocarcinoma [0.03%]
与奥西替尼敏感性相关的表皮生长因子受体突变型肺腺癌恶性特征PRDX1相关性研究
Wenying Jiang,Maonan Wang,Xiaoqian Yu et al.
Wenying Jiang et al.
The peroxiredoxin (PRDX) family, also known as the peroxidase family, consists of six members that participate in a variety of essential bio-processes in carcinogenesis. However, their molecular role in lung adenocarcinoma (LUAD) has not be...
Analysis of the Relationship Between NF-κB1 and Cytokine Gene Expression in Hematological Malignancy: Leveraging Explained Artificial Intelligence and Machine Learning for Small Dataset Insights [0.03%]
NF-κB1在血液系统肿瘤中与细胞因子基因表达关系的研究：利用解释型人工智能和机器学习对小样本数据的洞察
Jae-Seung Jeong,Hyunsu Ju,Chi-Hyun Cho
Jae-Seung Jeong
This study measures expression of nuclear factor kappa B (NF-κB)1 and related cytokine genes in bone marrow mononuclear cells in patients with hematological malignancies, analyzing the relationship between them with an integrated framework...
Application and research progress of artificial intelligence in allergic diseases [0.03%]
人工智能在过敏性疾病中的应用及研究进展
Hong Tan,Xuehua Zhou,Huajie Wu et al.
Hong Tan et al.
Artificial intelligence (AI), as a new technology that can assist or even replace some human functions, can collect and analyse large amounts of textual, visual and auditory data through techniques such as Reinforcement Learning, Machine Le...