Development Of the VAMPCT Score for Predicting Mortality in CKD Patients with COVID-19 [0.03%]
用于预测CKD患者COVID-19死亡率的VAMPCT评分的研发
Chaofan Li,Yue Niu,Xinyan Pan et al.
Chaofan Li et al.
Background: Chronic kidney disease (CKD) patients with coronavirus disease 2019 (COVID-19) are at significant risk of death. However, clinical identification of high-risk individuals remains suboptimal despite the recognition of many pathop...
Cracking Chordoma's Conundrum: Immune Checkpoints Provide a Potential Modality [0.03%]
破解软骨肉瘤难题：免疫检查点提供潜在治疗模式
Weihai Liu,Moksada Regmi,Xiaodong Chen et al.
Weihai Liu et al.
Objectives: Chordoma, a rare malignant tumor, is notably resistant to conventional treatments including chemotherapy, radiotherapy, and targeted approaches. Immunotherapy, successful in treating other cancer types, presents a promising aven...
Advantage of Tolerability following Arsenic Trioxide-VTD vs VRD in newly diagnosed multiple myeloma patients: a prospective, open-label study [0.03%]
三氧化二砷-VTD与VRD方案治疗新诊断多发性骨髓瘤患者的耐受性优势：一项前瞻性开放标签研究
Xinyu Zuo,Apeng Yang,Pingping Chen et al.
Xinyu Zuo et al.
Multiple myeloma is the second most common hematologic malignancy in older patients. The standard front-line VRD regimen (bortezomib/lenalidomide/dexamethasone) achieves high efficacy but is associated with significant toxicity, leading to ...
Identification of an Anoikis-associated LncRNA Signature to Predict the Clinical Prognosis and Immune Function of Patients with Endometrial Cancer [0.03%]
识别与 anoikis 相关的长链非编码rna特征以预测子宫内膜癌患者的临床预后和免疫功能
Guanxiao Chen,Ting Zhou,Xiaoyu Shen et al.
Guanxiao Chen et al.
Background: Endometrial cancer is a highly heterogeneous malignancy in women with high mortality, and patients diagnosed with advanced endometrial cancer have a poor prognosis. Anoikis is a form of programmed cell death that is important fo...
Screening and identification of versican as a sensitive biomarker and potential therapeutic target in basal cell carcinoma [0.03%]
基底细胞癌敏感生物标志物和潜在治疗靶点软骨素硫酸 proteoglycan 1 的筛选与鉴定
Wenlin Li,Yang Wang,Qiang Hu et al.
Wenlin Li et al.
Basal cell carcinoma (BCC) is the most common type of non-melanoma skin cancer (NMSC). However, few biomarkers have been developed for the diagnosis of BCC. This study aimed to uncover novel BCC biomarkers for diagnosis and treatment via tr...
The Immature Infant Liver: Cytochrome P450 Enzymes and their Relevance to Vaccine Safety and SIDS Research [0.03%]
不成熟肝脏的药酶学及对疫苗安全性研究和婴儿猝死综合症(SIDS)研究的意义
Gary S Goldman,Richard Z Cheng
Gary S Goldman
Aim and background: Vaccines are a cornerstone of modern medicine, significantly reducing morbidity and mortality worldwide. Their administration in infants requires consideration of physiological maturity. Cytochrome P450 (CYP450) enzymes,...
Risk of New-Onset Hidradenitis Suppurativa in People with Polycystic Ovary Syndrome: a large-scale propensity-score-matched cohort study [0.03%]
多囊卵巢综合征患者新发汗腺炎的发病风险：一项大样本倾向性匹配队列研究
Shuo-Yan Gau,Chia-Chi Chang,Wei-Ting Hsu et al.
Shuo-Yan Gau et al.
Background: Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease, while polycystic ovary syndrome (PCOS) is an endocrine disorder. Both conditions share common risk factors, such as androgen excess and obesity. This study ai...
Establishment of Reference Intervals for Serum Thyroid-related Hormones in the Chinese Oldest-old [0.03%]
我国百岁以上老人血清甲状腺相关激素参考区间建立
Dizhi Liu,Sihang Fang,Danni Gao et al.
Dizhi Liu et al.
Background: Thyroid function differs between the oldest-old and younger adults, however, there is a lack of appropriate RIs for the serum FT4, T4, FT3, T3, and TSH concentrations for the oldest-old. Methods: A total of 349 people was select...
The Uric Acid to Albumin Ratio Predicts All-cause and Cardiovascular Mortality Among U.S. Adults Results from the National Health and Nutrition Examination Survey in 2003-2018 [0.03%]
2003-2018年美国成人NHANES调查结果：尿酸与白蛋白比率可预测全因及心血管病死亡率
Guangyu Wang,Guangyu Li,Pengfei Wang et al.
Guangyu Wang et al.
Background: The association between the uric acid to albumin ratio (UAR) and mortality in the general population remains poorly understood. This study aimed to investigate the associations of UAR with all-cause and cardiovascular mortality ...
Pre-thrombectomy cerebral edema affects outcomes in acute stroke patients treated with thrombectomy [0.03%]
术前脑水肿影响接受取栓治疗的急性卒中患者预后
Lu Yang,Yuan Kan,Changhong Ren et al.
Lu Yang et al.
Objective: Cerebral edema significantly impacts the functional outcomes in patients with acute stroke treated with thrombectomy, especially those with an extended time window (6-24 hours). This study was to investigate whether pre-thrombect...