Validation of a Fall Predictive Model for Inpatients in Japanese Long Term Care Hospitals [0.03%]
日本长期护理医院住院患者跌倒预测模型的验证研究
Hitomi Shimada,Risa Hirata,Naoko E Katsuki et al.
Hitomi Shimada et al.
Background: The Saga Falls Risk Model 2 (SFRM2) is a simplified fall prediction model that we recently developed. It uses eight items that are easy to assess at the time of admission to an acute care hospital. However, patients in long-term...
Observational Study
International journal of medical sciences. 2025 Jun 9;22(12):2877-2883. DOI:10.7150/ijms.106600 2025
IL1A regulates MSU-induced apoptosis and inflammatory response through TLR4/MyD88/NF-κB signaling pathway [0.03%]
IL1A通过TLR4/MyD88/NF-κB信号通路调控MSU诱导的凋亡和炎症反应
Fei Pan,Yun Zhang,Min Li et al.
Fei Pan et al.
Background: The increased inflammation associated with interleukin-1α (IL-1A) induced by monosodium urate (MSU) crystal-induced gouty arthritis is mediated through the NLRP3 inflammasome and NF-κB signaling pathways. This study investigat...
An Overview of the Role of Genetic factors in Idiopathic Pulmonary Fibrosis: Insights from Epidemiology to Prognosis [0.03%]
特发性肺纤维化遗传因素的作用概述——从流行病学到预后的见解
Jiahao Liu,Zihan Yi,Ting Chen et al.
Jiahao Liu et al.
Idiopathic pulmonary fibrosis (IPF), a chronic progressive fibrosing interstitial lung disease with an unclear etiology, is characterized by progressive respiratory impairment and a median survival of 3-5 years. The pathophysiology associat...
Integration of Multi-Scale Profiling and Machine Learning Reveals the Prognostic Role of Extracellular Matrix-Related Cancer-Associated Fibroblasts in Lung Adenocarcinoma [0.03%]
多尺度分析和机器学习整合揭示细胞外基质相关癌症相关成纤维母细胞在肺腺癌预后的作用
Ziyi Chen,Mengyuan Chen,Changqing Yang et al.
Ziyi Chen et al.
Lung adenocarcinoma (LUAD) remains a leading cause of cancer mortality, necessitating novel therapeutic targets and prognostic strategies. This study investigates the role of extracellular matrix cancer-associated fibroblasts (eCAFs) and th...
NSUN2 rs13181449 variant decreases the risk of oral cancer development [0.03%]
NSUN2rs13181449变异降低口腔癌发病风险
Li-Chung Hung,Cheng-Chen Huang,Yen-Ting Lu et al.
Li-Chung Hung et al.
NOP2/Sun RNA methyltransferase 2 (NSUN2), encoded by the NSUN2 gene, is a nuclear RNA methyltransferase that catalyzes the methylation of cytosine to 5-methylcytosine (m5C). Although RNA modification has been widely discussed in cancer deve...
Niclosamide-Modulated Apoptosis and Autophagy in Breast Cancer Cells via Phosphorylated JNK as a Common Regulator [0.03%]
尼克利斯胺通过磷酸化JNK作为共同调节因子诱导乳腺癌细胞凋亡和自噬
Ming-Shan Chen,Tsung-Yi Chen,Shu-Hsin Chen et al.
Ming-Shan Chen et al.
Autophagy plays critical pro-survival and pro-apoptotic roles in regulating breast cancer death. Niclosamide is a U.S. FDA-approved drug that is used for parasite treatment. Exposure to niclosamide causes apoptosis in several different type...
Problematic Smartphone Use in Adolescents with Attention-Deficit/Hyperactivity Disorder: The Roles of Domestic Violence, Parenting Styles, and Peer Bullying Victimization [0.03%]
注意缺陷多动障碍青少年的手机成瘾问题：家庭暴力、父母教养方式和同伴欺凌受害角色分析
Po-Chun Lin,Cheng-Fang Yen,Ray C Hsiao et al.
Po-Chun Lin et al.
Background: Problematic smartphone use (PSU) was associated with the increased risk of mental health problems in adolescents. Studies have identified several individual factors related to PSU in adolescents with ADHD; however, environmental...
A Potential Predictor of Proximal Flow-Diverter Stent Jailed Artery Stenosis: Distal to Proximal Artery Diameter Ratio [0.03%]
jailed动脉狭窄潜在预测因子：远端动脉直径与近端动脉直径比值
Yudi Tang,Peike Chen,Jian Lv et al.
Yudi Tang et al.
Background: Flow-diverting stents (FDS) are widely used in the treatment of intracranial aneurysms. During treatment, many side branches-especially small ones-are inevitably covered, leading to narrowing and impaired bloo...
Investigation of the Relationship Between University Students' Nomophobia and Psychological Distress: A Cross-sectional Study [0.03%]
一项横断面研究调查了高校学生手机依赖与心理困扰之间的关系
Rakesh Kumar,Aisha Osman Yousif,Mohammed Ismail Humaida
Rakesh Kumar
Background: This study investigated the relationship between nomophobia, psychological distress, and demographic factors among students. Methods: This cross-sectional study used a convenience sampling approach to collect data from 723 respo...
Novel Genetic Variants in PATL 2 Corresponding to Different Clinical Phenotypes of Female Infertility [0.03%]
PATL2新突变导致不同临床表型的女性不孕症
Xiaotao Yang,Xiangrui Shi,Jing Wang et al.
Xiaotao Yang et al.
PATL2, an RNA-binding protein and a translational repressor, plays a crucial role in maintaining mRNA homeostasis during female gametogenesis and early development of embryos. Rare pathogenic variants of its encoding gene have been implicat...