Functional Impairment of Activated Regulatory T Cells as a Central Immunological Defect in Endometriosis [0.03%]
Yukiko Tanaka,Eiko Maeda,Hiroyuki Okimura et al.
Yukiko Tanaka et al.
Background: Endometriosis is increasingly recognized as a disorder of impaired reproductive immune tolerance rather than solely an endocrine disease. Although previous studies have reported inconsistent findings regarding...
Autoimmune Thyroid Disease and Female Fertility: Clinical Evidence on Ovarian Reserve, Infertility Treatment Outcomes, and Pathophysiology [0.03%]
Akira Iwase,Yuko Hasegawa,Yoshikazu Kitahara et al.
Akira Iwase et al.
Background: Thyroid autoimmunity (TAI) is prevalent among women of reproductive age and has been associated with impaired fertility; however, its effects on ovarian reserve and infertility treatment outcomes remain contro...
Tatsuya Kobayashi,Hiroshi Ishikawa,Hirokazu Tanaka et al.
Tatsuya Kobayashi et al.
Purpose: This study aimed to determine whether continuous aromatase inhibition with letrozole reduces peri-ovulatory responsiveness to ovulatory stimulation in in vitro-grown mouse follicles. ...
Uterine Endometrial Microbiome and Chronic Endometritis in Relation to Anti-β2-Glycoprotein I (β2GPI)/Human Leukocyte Antigen (HLA)-DR Autoantibodies in Women With Recurrent Implantation Failure and Recurrent Pregnancy Loss: A Cross-Sectional Study [0.03%]
抗β2糖蛋白I/人类白细胞抗原抗体与子宫内膜微生态及慢性子宫内膜炎的关系：横断面研究
Yosuke Ono,Hajime Ota,Maki Ogi et al.
Yosuke Ono et al.
Background: Anti-β2GPI/HLA-DR autoantibodies may be involved in recurrent implantation failure (RIF) and recurrent pregnancy loss (RPL). We examined their association with the endometrial microbiome and chronic endometri...
Expression and Function of Meflin in Human Endometrial Decidualization [0.03%]
人子宫内膜蜕膜化过程中Meflin的表达与功能作用机制研究
Naoki Inoue,Yumiko Tsukui,Akihito Morita et al.
Naoki Inoue et al.
Purpose: Decidualization of endometrial stromal cells involves significant morphological and functional changes in which alpha-smooth muscle actin (αSMA) expression decreases. Meflin, a glycosylphosphatidylinositol-ancho...
Toward Implantation-Assisting Technologies: Lessons From In Vivo and Ex Vivo Models [0.03%]
迈向植入辅助技术：来自体内和体外模型的经验教训
Takehiro Hiraoka,Yasushi Hirota,Masahito Ikawa
Takehiro Hiraoka
Background: Despite advances in assisted reproductive technology (ART), embryo implantation remains inefficient and represents a major barrier to successful pregnancy. Recurrent implantation failure persists even after tr...
Long-Read Sequencing of CAH and ADPKD Provides Novel Insights Into the Genetic Diagnosis of Male Infertility [0.03%]
长读序列为男性不育的遗传诊断提供新的视角：CAH和ADPKD的案例研究
Xiao Li,Chang Liu,Wen Liu et al.
Xiao Li et al.
Purpose: This study aimed to evaluate the utility of long-read sequencing (LRS) in identifying variants of congenital adrenal hyperplasia (CAH) and autosomal dominant polycystic kidney disease (ADPKD) in infertile men, wh...
Impact of Inner Cell Mass Hatching Levels Before Vitrification on Clinical Pregnancy in Preimplantation Genetic Testing for Euploidy Cycles [0.03%]
玻璃化冷冻前胚胎囊胚期内细胞团高低对整倍体胚胎移植妊娠结局的影响研究
Hsiu-Hui Chen,Chien-Hong Chen,Chun-Chia Huang et al.
Hsiu-Hui Chen et al.
Purpose: Does an association exist between the ICM/TE hatching levels of biopsied blastocysts before vitrification and implantation? Methods: ...
Advancements in Spermatogenesis In Vitro: From Murine Success to Human Applications [0.03%]
从鼠模型到人类应用：体外精子发生的进展
Maki Kamoshita
Maki Kamoshita
Background: Male infertility due to spermatogenic failure remains a global challenge. While in vitro spermatogenesis (IVS) offers potential for fertility preservation, recapitulating the complex, species-specific testicul...
Are the Previously Reported Risk Factors for Endometriosis Actually Associated With Pain and Infertility Rather Than Endometriosis Itself? [0.03%]
之前报道的子宫内膜异位症危险因素实际上是与疼痛和不孕症相关还是与子宫内膜异位症本身相关？
Sachiko Matsuzaki
Sachiko Matsuzaki
Background: Endometriosis is often diagnosed late due to a lack of noninvasive diagnostic tools and the varied presentation of its symptoms. Identifying risk factors for endometriosis is crucial for reducing diagnosis del...