Comprehensive Genomic Characterization Between Urothelial Carcinoma Subtypes/Divergent Differentiation (S/DD) and Pure Urothelial Carcinoma Using a Large-Scale Japanese Genomic Panel Dataset [0.03%]
基于大规模日本基因组面板数据集对尿路上皮癌亚型/分化方向偏离（S/DD）和纯尿路上皮癌进行综合基因组特征分析
Go Kobayashi,Yohei Sekino,Shunsuke Miyamoto et al.
Go Kobayashi et al.
Objectives: Urothelial carcinoma (UC) is a common malignancy; however, UC subtypes/divergent differentiation (S/DD) accounts for only 10%-20% of overall cases. S/DD's aggressive biological behavior significantly affects i...
Prognostic Value of Inflammatory Biomarkers as Continuous Variables in Metastatic Renal Cell Carcinoma: Linearity Assessment, Proportional Hazards Assumption Testing, and Time-Varying Effects [0.03%]
炎症生物标志物在转移性肾细胞癌中的预后价值：连续变量评估、比例风险假设检验和时间变化效应
Shugo Yajima,Soichiro Yoshida,Shohei Fukuda et al.
Shugo Yajima et al.
Objectives: To evaluate inflammatory biomarkers (neutrophil-to-lymphocyte ratio [NLR], C-reactive protein [CRP]) as continuous variables and assess linearity and the proportional hazards (PH) assumption, including time-va...
Younger Age Is Associated With Early Urinary Continence Recovery After Robot-Assisted Radical Prostatectomy [0.03%]
年轻与机器人辅助前列腺癌根治术后早期恢复尿控有关
Hiroki Hagimoto,Masashi Kubota,Kei Mizuno et al.
Hiroki Hagimoto et al.
Objectives: To evaluate whether an age < 55 years is independently associated with early urinary continence recovery after robot-assisted radical prostatectomy (RARP) in a large multi-institutional Japanese cohort. ...
Sarcopenia Weakens the Benefit of Bacillus Calmette-Guérin in Non-Muscle-Invasive Bladder Cancer: A Computed Tomography-Based Cohort Study [0.03%]
肌肉减少症削弱了卡介苗在非肌层浸润性膀胱癌中的疗效：一项基于CT的队列研究
Nobutaka Nishimura,Makito Miyake,Tomoharu Iwao et al.
Nobutaka Nishimura et al.
Objectives: Non-muscle-invasive bladder cancer (NMIBC) commonly recurs despite intravesical Bacillus Calmette-Guérin (BCG) therapy. Host factors that modify the effectiveness of BCG have not been completely defined. We e...
Tarun Jindal,Monika Meena
Tarun Jindal
Transvesicoscopic Reconstruction for Duplex Ectopic Ureterocele: A Minimally Invasive Alternative to Open Surgery [0.03%]
输尿管膀胱返折部异位开口积水的腔内重建手术：一种微创替代开放性手术的方法
Kazuyoshi Johnin,Yuri Mori,Kenichi Kobayashi et al.
Kazuyoshi Johnin et al.
Ectopic ureterocele in duplex systems is commonly treated with open reconstruction, despite advances in minimally invasive pediatric urology. We developed a fully intravesical transvesicoscopic technique that reproduces key elements of open...
Impact of Early Relative Dose Intensity on Survival in Patients Receiving Enfortumab Vedotin for Metastatic Urothelial Carcinoma: A Japanese Real-World Multicenter Study [0.03%]
恩美曲妥珠单抗治疗转移性尿路上皮癌患者早期相对剂量强度对其生存的影响：一项日本多中心真实世界研究
Yuki Endo,Yuma Sakura,Go Kaneko et al.
Yuki Endo et al.
Objective: This study aimed to evaluate the clinical relevance of early relative dose intensity (eRDI) during enfortumab vedotin (EV) monotherapy in patients with metastatic urothelial carcinoma (mUC) based on a Japanese ...
Cancer-Associated Fibroblasts Promote Development of Papillary Renal Cell Carcinoma by Inducing Histone Lactylation of RBM15B to Modify in an m6A-Dependent Manner on ANLN [0.03%]
癌相关成纤维细胞通过诱导RBM15B组蛋白乳酸化促进乳头状肾细胞 carcinoma发育并以m6A依赖性方式修饰ANLN
Jiawei Shen,Peng Yu,Wenfa Mo et al.
Jiawei Shen et al.
Objectives: Renal papillary cell carcinoma (pRCC) is a prevalent subtype of kidney cancer with unclear pathogenesis and limited therapeutic options. The Anillin protein plays critical roles in cell division and cytoskelet...
Impact of Absolute PSA Value and Relative PSA Response Rate on Overall Survival in Patients With Metastatic Castration-Sensitive Prostate Cancer Treated With Androgen Receptor Signaling Inhibitors [0.03%]
绝对PSA值和相对PSA反应率对接受AR信号抑制剂治疗的转移性雄激素敏感性前列腺癌患者总生存期的影响
Toru Suzuki,Takahiro Fukuda,Kosuke Nishizaki et al.
Toru Suzuki et al.
Background: Although the relationship between prostate-specific antigen (PSA) kinetics and prognosis in metastatic castration-sensitive prostate cancer (mCSPC) cases has been examined in a pivotal randomized control trial...
Fully Extraperitoneal Robotic Sacrohysteropexy Compared With Transperitoneal Robotic Sacrocervicopexy for Anterior and Apical Pelvic Organ Prolapse [0.03%]
全腹膜外机器人骶骨子宫悬吊术与经腹膜机器人骶骨阴道悬吊术治疗盆腔器官前向和顶蓬疝的比较研究
Shingo Moriyama,Kazue Ogawa,Masafumi Katakura et al.
Shingo Moriyama et al.
Objectives: To evaluate the feasibility, safety, and short‑term outcomes of fully extraperitoneal robotic sacrohysteropexy (EP‑RSH) compared with transperitoneal robotic sacrocolpopexy (RSC) for anterior and apical pelv...