Ryotaro Sakio,Tamaki Miura,Atsushi Kihara et al.
Ryotaro Sakio et al.
The molecular mechanisms underlying metastasis still remain unclear. We previously established a suspension culture using low-attachment culture dishes and demonstrated that cell lines adapted through 2 months suspension culture (termed FL ...
Human Intestinal Spirochetosis Shows Higher Positivity in Sessile Serrated Lesions Than in Tubular Adenomas With Preferential Colonization of Absorptive Epithelium [0.03%]
结肠息肉中空肠弯曲菌的感染率及细胞嗜性研究
Hisanori Matoba,Mai Iwaya,Chifumi Fujii et al.
Hisanori Matoba et al.
Factors underlying differential colonization by human intestinal spirochetosis (HIS) of various colorectal neoplastic lesions remain unclear. We compared HIS positivity and colonization patterns between sessile serrated lesions (SSLs) and t...
Immunohistochemistry for p16 and p53 Provides Substantial Agreement With Molecular Tests in Penile Cancer [0.03%]
p16和p53免疫组化与阴茎癌分子检测结果一致性高
Jan Hrudka,Jan Hojný,Eva Krkavcová et al.
Jan Hrudka et al.
Penile squamous cell carcinoma (pSCC) is a rare cancer associated with a relatively poor prognosis. The WHO classifies pSCC into HPV-associated and HPV-independent subtypes, with HPV-positive pSCCs showing slightly better outcomes. A key ne...
Low Expression of Cell Adhesion Molecule 1 in Resected Gastroenteropancreatic Neuroendocrine Tumors: Relationship With Lymph Node and Distant Metastasis [0.03%]
胃肠胰神经内分泌肿瘤切除标本中细胞黏附分子-1低表达与淋巴结、远处转移的关系
Ken Miyabe,Michinobu Umakoshi,Yukitsugu Kudo-Asabe et al.
Ken Miyabe et al.
Gastroenteropancreatic neuroendocrine tumors (GEP-NETs) are clinically heterogeneous, making prediction of metastatic behavior challenging. This study examined Cell Adhesion Molecule 1 (CADM1) and the differentially expressed in adenocarcin...
Morphologic Fault Lines in Distinguishing Gastric Cancer pTis From pT1a in Endoscopic Submucosal Dissection Specimens: An Interobserver Study [0.03%]
内镜黏膜下剥离标本中鉴别胃癌pTis与pT1a的形态学界限：一项观察者间的比较研究
Rika Omote,Kohei Okura,Eita Kumagai et al.
Rika Omote et al.
The 16th edition of the Japanese Classification of Gastric Carcinoma newly distinguishes pTis from pT1a to improve international translatability with the WHO classification and UICC TNM system. However, the histologic boundary between intra...
Cancer-Associated Fibroblasts in Invasion Front Can be a Prognostic Predictor for Oral Squamous Cell Carcinoma [0.03%]
癌相关成纤维细胞作为口腔鳞状细胞 carcinoma 侵袭前哨的预后标志物
Yuuki Ishii,Joaquim Carreras,Yukie Yara Kikuchi et al.
Yuuki Ishii et al.
Tumor immune microenvironment (TME) is an important pathogenic component in cancer, and a therapeutic target. To examine the role of the TME, especially cancer-associated fibroblasts (CAFs) in oral squamous cell carcinoma (SCC), a retrospec...
Effect of the Mutual Interaction of GPNMB and LPAR1 on Cellular Motility and Tumorigenicity in Mammary Epithelial Cells [0.03%]
GPNMB和LPAR1互作对乳腺上皮细胞迁移能力和致瘤能力的影响
Minori Kimura,Yukari Okita,Erina Iwabuchi et al.
Minori Kimura et al.
Glycoprotein non-metastatic melanoma protein B (GPNMB) is a poor prognostic factor, which is highly expressed in many types of malignant tumors, including breast cancer. Previously, the overexpression of GPNMB was shown to confer tumorigeni...
Advances in Visualizing Cytosine Methylation and Allele-Specific Epigenetic States in Tissue Context [0.03%]
组织水平下胞嘧啶甲基化及等位基因特异性表观遗传状态可视化研究取得进展
Sohei Kitazawa,Ryuma Haraguchi,Riko Kitazawa
Sohei Kitazawa
Epigenetic regulation represents a heritable, sequence-independent layer of transcriptional control that critically shapes tissue morphology throughout development, homeostasis, and disease. Although immunohistochemical detection of histone...
Carcinogenicity of Dimethylarsinic Acid: Evidence From Experimental Models and Mechanistic Insights [0.03%]
次甲基砷酸致癌性：来自实验模型和机制启示的证据
Hideki Wanibuchi
Hideki Wanibuchi
Arsenic is a well-established human carcinogen and a major global environmental health concern. However, the mechanisms underlying arsenic-induced carcinogenesis remain incompletely understood. This review focuses on dimethylarsinic acid (D...
Histopathological Examination of Pancreatectomy Specimens From Patients With Locally Advanced Pancreatic Adenocarcinoma Following Endoscopic Ultrasound-Guided Phosphorus-32 (32P) Implantation and Chemotherapy [0.03%]
内镜超声引导下磷-32植入和化疗后局部晚期胰腺癌手术标本的病理检查
A H Lim,A Ruszkiewicz,N Rodgers et al.
A H Lim et al.
Despite increasing utilisation of brachytherapy for pancreatic cancer, literature on its histopathological effect is sparse. We evaluated the histopathological response and distribution of phosphorus-32 (32P) microparticles in resected loca...