Kenjiro Hosaka,Yoji Hirano
Kenjiro Hosaka
Altered IRF1-miR-20a-5p regulatory axis in the hippocampus of patients with major depressive disorder [0.03%]
抑郁症患者海马区IRF1-miR-20a-5p调控轴的改变
Mariko Okano,Yuta Yoshino,Anuj K Verma et al.
Mariko Okano et al.
Aim: Neuroinflammation has been implicated in the pathogenesis of major depressive disorder (MDD), with interferon regulatory factor 1 (IRF1) playing a potential role. MicroRNAs (miRs) are also involved in MDD through pos...
Nature, nurture, and 5-HT4R: Familial predisposition, not parental bonding, is associated with brain 5-HT4R in a sex-specific manner [0.03%]
自然与养育以及5-ht4r：家族易感性（而不是父母抚育）以性别特异的方式与大脑5-ht4r相关
Randi T Kjær,Martin B Jørgensen,Kristian H R Jensen
Randi T Kjær
Background: Major depressive disorder (MDD) aggregates in families. The neostriatum, key to reward and attachment circuits, has the highest density of serotonin 4 receptors (5-HT4R). Striatal 5-HT4R is low in MDD and link...
Hyperconnectivity and network inflexibility in large-scale brain networks: Linking childhood neglect to depression via task and resting-state fMRI [0.03%]
大范围脑网络中超连接与网络僵化：通过任务态和静息态fMRI联结儿童期忽视与抑郁的关系
Xinyu Cao,Huihui Yang,Zhaoxia Liu et al.
Xinyu Cao et al.
Background: Childhood neglect is a potent risk factor for major depressive disorder (MDD), yet its underlying neural mechanisms linking neglect to depression remain poorly understood. This study aimed to investigate brain...
Hypnotic discontinuation is not synonymous with successful deprescribing: A Taiwan perspective [0.03%]
从台湾视角看，催眠药物的停用并不等同于成功减药
Lien-Chung Wei,Ding-Lieh Liao
Lien-Chung Wei
This article relates to Higher discontinuation with dual orexin receptor antagonists than with benzodiazepines: A Japanese claims cohort study. © 2026 T...
Fractal dynamics in spontaneous motor activity associate with effective antidepressant chronotherapeutic response, cerebellar volumes, and white matter microstructure in bipolar disorder [0.03%]
分形动力学与自发运动活动关联于双相情感障碍中的有效抗抑郁药物chrono疗法反应、小脑体积和白质微结构
Chiara Verga,Beatrice Bravi,Edoardo Venturelli et al.
Chiara Verga et al.
Aim: Bipolar disorder (BD) is characterized by circadian dysregulation, altered sleep-wake behaviors, and heterogeneous antidepressant response. Chronotherapeutic interventions such as total sleep deprivation combined wit...
Longitudinal MRI studies of children with attention-deficit/hyperactivity disorder: A systematic review [0.03%]
注意缺陷多动障碍儿童的纵向磁共振成像研究：系统综述
Ayaka Ishii-Takahashi,Yuzu Yoshimaru,Dwi Muhammad et al.
Ayaka Ishii-Takahashi et al.
We reviewed longitudinal magnetic resonance imaging (MRI) studies exploring the brain development of children with attention-deficit/hyperactivity disorder (ADHD). Specifically, we conducted a systematic review of papers published until 9 S...
Different effects of social cognitive skills training in schizophrenia and autism spectrum disorder: A rater-blinded, multicenter, randomized controlled trial [0.03%]
社会认知技能训练在精神分裂症和自闭症谱系障碍中的不同效果：盲法评价者、多中心随机对照试验
Sadao Otsuka,Satsuki Oe,Sumie Yamada et al.
Sadao Otsuka et al.
Aim: Schizophrenia (SCZ) and autism spectrum disorder (ASD) are both characterized by social cognitive impairments that strongly predict poor functional outcomes. However, evidence-based social cognitive interventions hav...
Unrecognized sleep-related hypermotor epilepsy emerging in a patient with REM sleep behavior disorder: A case report [0.03%]
以快速动眼睡眠行为障碍出现的未被认识的与快动眼睡眠相关的肌阵挛性癫痫一例报告
Takashi Fukao,Masaki Fujiwara,Kazuhide Nakanishi et al.
Takashi Fukao et al.
Shuhei Hara,Keita Suzuki,Akio Murakami et al.
Shuhei Hara et al.
Aim: In schizophrenia, disrupted perceptual processes contribute to positive symptoms. However, it remains unclear how top-down priors and bottom-up likelihoods are represented across the hierarchy of visual cortices. To ...