Nature, nurture, and 5-HT4R: Familial predisposition, not parental bonding, is associated with brain 5-HT4R in a sex-specific manner
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Background: Major depressive disorder (MDD) aggregates in families. The neostriatum, key to reward and attachment circuits, has the highest density of serotonin 4 receptors (5-HT4R). Striatal 5-HT4R is low in MDD and linked to fa... ...
